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Janet Daly

Associate Professor in Emergent Viruses, Faculty of Medicine & Health Sciences

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Biography

Janet Daly obtained a BSc (Hons) in Animal Physiology and Nutrition from the University of Leeds. She then worked as a laboratory technician at the Animal Health Trust for a year before beginning part-time study towards a PhD on equine influenza. After gaining her PhD in 1995, she moved into the human influenza field, first at the National Institute of Biological Standards and Control, then at Glaxo Wellcome (now Glaxo Smithkline). She returned to the Animal Health Trust in 2001 where she built up the influenza group over the next 5 years. Although she then moved to the University of Liverpool to study immunopathology of Japanese encephalitis virus, she maintained her involvement in equine virology. After a brief spell as a medical writer, she joined the School of Veterinary Medicine and Science in 2009. She was Module Convenor for the Personal and Professional Skills Modules (years 1 and 2) for 5 years before being appointed BVMedSci Programme Lead.

Expertise Summary

  • Epidemiology and evolution of viruses
  • Development and testing of viral vaccines, antivirals and diagnostics
  • Science communication

A list of publications can be seen on Google Scholar

Teaching Summary

Programme Lead (BVMedSci)

Undergraduate teaching (BVM BVS)

  • Academic integrity and plagiarism
  • Immunological assays
  • Equine respiratory physiology
  • Scientific writing
  • Haemostatic disorders
  • Information technology
  • Animal Handling (small mammal and equine)

Additional

  • Numeracy
  • NUVACS (communication skills) facilitator
  • Postgraduate training (EndNote)

Research Summary

My expertise is in the field of emerging / re-emerging RNA viruses. I have extensive experience of strain surveillance of equine influenza viruses and has worked closely with veterinary vaccine… read more

Recent Publications

Science Communication

Undergraduate research projects

  • An investigation into the prevalence of house dust mites in the equine environment (2010)
  • An investigation into the occurrence of Staphylococcus on the hair of ferrets without dermatological disease (2010)
  • Mosquitoes as vectors of disease within the British Isles with particular reference to the Flaviviruses: molecular methods for their surveillance (2010)
  • The development of PCR primers for the identification of British mosquito species (2011)
  • The impact of increased exercise and dietary supplementation on weight loss in the obese equine (2011)
  • Characterization of a model of canine atopic dermatitis in terms of changes to skin barrier function (2011)
  • Characterization of the cutaneous microbiological populations in a model of canine atopic dermatitis (2011)
  • Survey for potential Schmallenberg virus vectors (2012)
  • Influence of obesity on immune responses of equids to influenza vaccination (2012)
  • Is colonization with methicillin-resistant Staphylococcus an occupational risk for veterinary students and clinicians? (2012)
  • Factors in transmission of equine influenza virus to dogs (2012)
  • Contact networks and the spread of infectious disease in equine populations (2013)
  • Refinement of a canine atopic dermatitis model (2013)
  • A study into the seroprevalence of Schmallenberg virus among ruminants in the United Kingdom, November 2011-July 2013 (2013)
  • Surveillance of UK dogs for antibodies to influenza viruses (2014)
  • Increase of allergic window in canine house dust mite allergic dog model (2014)
  • An evaluation of the usefulness of published diagnostic criteria for canine atopic dermatitis in a UK-based population of breeds used as assistance dogs (2014)
  • A study to determine if sheep are at a higher risk of infection with Schmallenberg virus than cattle (2014)
  • Examining cytokine profiles in canine and equine cells in response to infection with influenza A viruses (2015)
  • Correlation between serum fatty acid levels and influenza vaccination in donkeys

Current Research

My expertise is in the field of emerging / re-emerging RNA viruses. I have extensive experience of strain surveillance of equine influenza viruses and has worked closely with veterinary vaccine manufacturers in the conduct of clinical trials. An outcome of my PhD studies was the establishment of a formal vaccine strain selection system for equine influenza vaccines similar to that for human influenza. In collaboration with mathematical modellers, I have been involved in the development of models to predict the likelihood of vaccine breakdown and occurrence of outbreaks in equine populations (e.g. Park, Daly et al. Science 2009:326:726-8). In the field of human influenza, I was involved in developing a cell-based susceptibility assay for neuraminidase inhibitors of influenza. I also studied the genetic and immunological safety of influenza DNA vaccines. The interspecies transmission of equine influenza to dogs (Daly et al. Emerg. Inf. Dis. 2008:14:461) ignited an interest in understanding the molecular and cellular pathogenesis, host range restrictions and transmissibility of influenza viruses. I also gained expertise in Flaviviridae at the University of Liverpool, and am currently applying expertise gained working with influenza viruses to members of the flavivirus family.

School of Veterinary Medicine and Science

University of Nottingham
Sutton Bonington Campus
Leicestershire, LE12 5RD

telephone: +44 (0)115 951 6116
fax: +44 (0)115 951 6415
email: veterinary-enquiries@nottingham.ac.uk