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Janet Daly

Associate Professor in Emergent Viruses, Faculty of Medicine & Health Sciences

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Biography

Janet Daly obtained a BSc (Hons) in Animal Physiology and Nutrition from the University of Leeds. She then worked as a laboratory technician at the Animal Health Trust for a year before beginning part-time study towards a PhD on equine influenza. After gaining her PhD in 1995, she moved into the human influenza field, first at the National Institute of Biological Standards and Control, then at Glaxo Wellcome (now Glaxo Smithkline). She returned to the Animal Health Trust in 2001 where she built up the influenza group over the next 5 years. Although she then moved to the University of Liverpool to study immunopathology of Japanese encephalitis virus, she maintained her involvement in equine virology. After a brief spell as a medical writer, she joined the School of Veterinary Medicine and Science in 2009. She was Module Convenor for the Personal and Professional Skills Modules (years 1 and 2) for 5 years before being appointed BVMedSci Programme Lead.

Expertise Summary

  • Epidemiology and evolution of viruses
  • Development and testing of viral vaccines, antivirals and diagnostics
  • Science communication

A list of publications can be seen on Google Scholar

Teaching Summary

Programme Lead (BVMedSci)

Undergraduate teaching (BVM BVS)

  • Academic integrity and plagiarism
  • Immunological assays
  • Equine respiratory physiology
  • Scientific writing
  • Haemostatic disorders
  • Information technology
  • Animal Handling (small mammal and equine)

Additional

  • Numeracy
  • NUVACS (communication skills) facilitator
  • Postgraduate training (EndNote)

Research Summary

My main research interests are in emerging and re-emerging RNA viruses, particularly zoonotic viruses such as influenza A viruses and the flaviviruses (Dengue, Japanese encephalitis, West Nile and… read more

Recent Publications

  • HOVER, SAMANTHA, KING, BARNABAS, HALL, BRADLEY, LOUNDRAS, ELENI-ANNA, TAQI, HUSSAH, DALY, JANET, DALLAS, MARK, PEERS, CHRIS, SCHNETTLER, ESTHER, MCKIMMIE, CLIVE, KOHL, ALAIN, BARR, JOHN N. and MANKOURI, JAMEL, 2016. Modulation of Potassium Channels Inhibits Bunyavirus Infection JOURNAL OF BIOLOGICAL CHEMISTRY. 291(7), 3411-3422
  • KINSLEY, REBECCA, SCOTT, SIMON D and DALY, JANET M, 2016. Controlling equine influenza: traditional to next generation serological assays Veterinary microbiology. 187, 15-20
  • SÁNCHEZ-VIZCAÍNO, FERNANDO, DALY, JANET M, JONES, PHILIP H, DAWSON, SUSAN, GASKELL, ROSALIND, MENACERE, TAREK, HEAYNS, BETHANEY, WARDEH, MAYA, NEWMAN, JENNY, EVERITT, SALLY and OTHERS, 2016. Small animal disease surveillance: respiratory disease Veterinary Record. 178(15), 361-364
  • DALY, JANET M, 2016. Making sense of altmetrics Equine veterinary journal. 48(4), 399-400

Science Communication

Undergraduate research projects

  • An investigation into the prevalence of house dust mites in the equine environment (2010)
  • An investigation into the occurrence of Staphylococcus on the hair of ferrets without dermatological disease (2010)
  • Mosquitoes as vectors of disease within the British Isles with particular reference to the Flaviviruses: molecular methods for their surveillance (2010)
  • The development of PCR primers for the identification of British mosquito species (2011)
  • The impact of increased exercise and dietary supplementation on weight loss in the obese equine (2011)
  • Characterization of a model of canine atopic dermatitis in terms of changes to skin barrier function (2011)
  • Characterization of the cutaneous microbiological populations in a model of canine atopic dermatitis (2011)
  • Survey for potential Schmallenberg virus vectors (2012)
  • Influence of obesity on immune responses of equids to influenza vaccination (2012)
  • Is colonization with methicillin-resistant Staphylococcus an occupational risk for veterinary students and clinicians? (2012)
  • Factors in transmission of equine influenza virus to dogs (2012)
  • Contact networks and the spread of infectious disease in equine populations (2013)
  • Refinement of a canine atopic dermatitis model (2013)
  • A study into the seroprevalence of Schmallenberg virus among ruminants in the United Kingdom, November 2011-July 2013 (2013)
  • Surveillance of UK dogs for antibodies to influenza viruses (2014)
  • Increase of allergic window in canine house dust mite allergic dog model (2014)
  • An evaluation of the usefulness of published diagnostic criteria for canine atopic dermatitis in a UK-based population of breeds used as assistance dogs (2014)
  • A study to determine if sheep are at a higher risk of infection with Schmallenberg virus than cattle (2014)
  • Examining cytokine profiles in canine and equine cells in response to infection with influenza A viruses (2015)
  • Correlation between serum fatty acid levels and influenza vaccination in donkeys

Current Research

My main research interests are in emerging and re-emerging RNA viruses, particularly zoonotic viruses such as influenza A viruses and the flaviviruses (Dengue, Japanese encephalitis, West Nile and Zika) but also including, orthobunyaviruses more recently.

I am fascinated with the complex interactions between viruses and their host and how studying these can lead to better understanding of determinants of viral pathogenicity. I also have an interest in factors influencing interspecies transmission and the use of mathematical models to further understanding of disease transmission. Recent projects have focused on development of serological assays.

Current / recent grants held include:

Medical Research Council / Wellcome Trust (2015-2016) Zika: Harnessing plant power for rational design of immunogens for use in diagnostic assays.

Pet Plan Charitable Trust (2015-2016) Characterisation of canine parvovirus strains circulating in the UK.

BBSRC (2015-2016) Application of next generation phage display technology to development of a Differentiation of Infected from Vaccinated Animals (DIVA) strategy.

BBSRC (2014-2018) India Partnering Award: Collaboration on Diagnosis of Emerging Viruses (CoDEV).

I also get involved in a wider range of research areas through undergraduate research projects and am a member of the Education Research Group (see Teaching and Learning).

See the Animal Infection and Immunity research theme web page for more information on virus research within SVMS.

School of Veterinary Medicine and Science

University of Nottingham
Sutton Bonington Campus
Leicestershire, LE12 5RD

telephone: +44 (0)115 951 6116
fax: +44 (0)115 951 6415
email: veterinary-enquiries@nottingham.ac.uk