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Image of Kin-Chow Chang

Kin-Chow Chang

Professor of Veterinary Molecular Medicine, Faculty of Medicine & Health Sciences

Contact

  • workRoom A14a Veterinary Academic Building
    Sutton Bonington Campus
    Sutton Bonington
    Leicestershire
    LE12 5RD
    UK
  • work0115 951 6491

Biography

Kin-Chow Chang qualified as a veterinary surgeon from the University of Bristol. He carried out post-graduate research training at University College London (MSc with Distinction in 1987), and at the Royal Veterinary College (PhD in 1990). He remained at the RVC as a Wellcome Trust Postdoctoral Fellow until 1995 when he joined the Roslin Institute as a Principal Investigator working on the molecular biology and genetics of skeletal muscle. He subsequently took up a senior lectureship at the University of Glasgow veterinary school becoming a Reader in 2006. He joined Nottingham in 2008 as Professor of Veterinary Molecular Medicine with active research programmes on skeletal muscle biology and host resistance to influenza viruses.

Expertise Summary

Prof. Chang is a Fellow of the Royal College of Veterinary Surgeons, and a Visiting Professor of Liaoning Medical University, China. He is a member of the Portuguese Animal and Veterinary Sciences Research Committee, Foundation for Science and Technology (FCT) and a member of the scientific committee of the Petplan Charitable Trust. He was a member of the BBSRC Agri-Food Research Committee. He is a member of the School's Research Committee and convenor of the 4th year veterinary module of Veterinary Public Health.

Research Summary

Molecular basis of phenotype determination in skeletal muscle of target animal species

We have a substantial research programme on understanding the basic and strategic biology of muscle development and growth in farm and model animals. A principal output of farm animal production is skeletal muscle. We conduct fundamental research on a highly strategic area that is important to food production in terms of meat quality and quantity, and to human health and well-being in relation to muscle hypertrophy and muscle as a major organ of innate immunity.

Mammalian host innate resistance to highly pathogenic influenza virus infection

Influenza A virus infection is a major veterinary disease that affects a wide range of mammalian and avian species, and is a serious zoonotic threat to public health. We have a major research programme on understanding the mechanisms of host innate disease resistance to influenza infections. Our strategic approach is to compare host response to virulent influenza virus infection (such as H5N1 virus) between resistant (e.g. pig and duck) and susceptible (human and chicken) species to identify targets for the development of intervention therapy to reduce disease severity.



Recent Publications

School of Veterinary Medicine and Science

University of Nottingham
Sutton Bonington Campus
Leicestershire, LE12 5RD

telephone: +44 (0)115 951 6116
fax: +44 (0)115 951 6415
email: veterinary-enquiries@nottingham.ac.uk