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Cardiovascular Disease

vascularplexiformlesion

Current projects include investigations into cardiac valve disease, particularly the molecular mechanisms underpinning valvular regurgitation and dynamic function in equines and companion animals (Bowen, Hallowell, Cobb, James), the role of embryonic myosin heavy chain and ANF in early heart development (Rutland), HIV-related pulmonary hypertension in a nonhuman primates (White), the impact of chronic heart failure on adipose tissue structure and physiology and functional plasticity following rescue by cardiac-specific gene therapy (Mostyn), and blood pressure control and inflammatory markers in dogs with cardiac disease (White).

SVMS academic leads:

SVMS Investigators:

Example active projects in cardiovascular disease in SVMS:

Title: Blood pressure control and inflammatory markers in dogs with cardiac disease
Lead Investigator:  Mrs Kate White (SVMS)
Co-investigators: SVMS partner practices

Title: HIV-related pulmonary hypertension in a nonhuman primate model
Lead Investigator: Dr Patricia George and Dr Karen Norris, Division of Pulmonary, Allergy, and Critical Care, University of Pittsburgh
Co-investigators: Dr Alexandra Brower (SVMS). Funding: NIH

Title: Impact of chronic heart failure on adipose tissue structure and physiology, and functional plasticity following rescue by cardiac-specific gene therapy
Lead Investigator: Dr Alison Mostyn (SVMS)
Co-investigators: Dr Alexander Lyon, (Walport Clinical Lecturer in Cardiology, Imperial College, University of London)

Title: Histology of captive macaque pulmonary vasculature
Lead Investigator: Dr Alexandra Brower (SVMS)
Co-investigators: Dr Patricia George and Dr Karen Norris, Division of Pulmonary, Allergy, and Critical Care, University of Pittsburgh. Funding: NIH

School of Veterinary Medicine and Science

University of Nottingham
Sutton Bonington Campus
Leicestershire, LE12 5RD

telephone: +44 (0)115 951 6116
fax: +44 (0)115 951 6415
email: veterinary-enquiries@nottingham.ac.uk