School of Veterinary Medicine and Science
   
   
  

Hiba Ibrahim

Email:

svxhi@nottingham.ac.uk

Room:

B32

Biography:

I graduated from the University of Khartoum in Sudan in 1994 as a veterinary surgeon, having attained a BA in Veterinary Science.  In 1996 I started to work as a teaching assistant at the Sudan University for Science and Technology in the Veterinary medicine department and worked into general practice as a veterinary surgeon at the university clinic. In 2000 I started my Masters degree on the prevalence of Dermatophilus congolensis in bovine and finished the research after further 2 years. In 2004 I worked on a research on the incidence of Trypanosmosis transmitted by Tabanus in Khartoum state.  In 2010, I started 4 years PhD on the effect of vasoactive intestinal peptide as anti-inflammatory agent on the sepsis syndrome caused by gram negative Salmonellosis.

Degree Registration:

BVSc, MVSc

School Research Theme:

Animal Infection and Immunity

Research Topic:

The therapeutic potential of vasoactive intestinal peptide in human gram negative induced sepsis

Summary of Research:

Sepsis is one of the diseases that have a global importance as it had the highest death toll. And all ages are prone to the disease. It is frequently associated with Gram-negative infections and sometimes with intestinal problems although the cause of a significant proportion of cases is unknown. The therapeutic potential of VIP has been shown against infectious diseases such as experimentally induced colitis and keratitis is mice, human rheumatoid arthritis and septic shock. We are studying the role of VIP in controlling sepsis which frequently accompanies infectious disease caused by Gram-negative bacteria; it is characterised by a systemic inflammatory response syndrome following release of microbial inflammatory material from bacterial cells, especially LPS which induces a potent inflammatory response. The annual mortality rate due to sepsis in the United Kingdom is higher than the rate due to lung cancer, breast cancer and bowel cancer combined. Salmonella enterica serovars are the cause of gastrointestinal inflammation in man but several serotypes also produce a systemic typhoid disease in man or animals where sepsis is typically present in the later stages of the disease.

Research Supervisors:

Dr Neil Foster

Prof Paul Barrow

Primary Funding Source:

Personal funding; Faculty for the future (Schlumberger), Gordon memorial and Sudan University for Science and Technology

Publications:

 

 

 

School of Veterinary Medicine and Science

University of Nottingham
Sutton Bonington Campus
Leicestershire, LE12 5RD

telephone: +44 (0)115 951 6116
fax: +44 (0)115 951 6415
email: veterinary-enquiries@nottingham.ac.uk