1.3 Most receptors are on the cell surface

Water-soluble signalling molecules cannot cross the membrane lipid bilayer, but bind to specific receptors embedded in the plasma membrane. The receptors have an extracellular domain that binds the signalling molecule, a hydrophobic transmembrane domain and an intracellular domain.

Binding of a ligand induces a conformational change in the receptor, in particular that of its intracellular region. It is this conformational change that activates a relay of intracellular signalling molecul
Author(s): The Open University

License information
Related content

Copyright © 2013 The Open University

Virtual Maths - Numbers, 3D Cylinder simulation tool
Interactive simulation tool demonstrating the formula for calculating the volume of a 3D cylinder
Author(s): Leeds Metropolitan University

License information
Related content

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Coastal Walk - Stop 11
The stretch of coastline between Slapton Sands and Start Point lighthouse is one of the most beautiful and interesting in the UK. In this podcast, we take you along the way, combining fascinating snippets of information about the natural history, geography, geology and history of the area. Presented by Dr Phil Bradfield, Open University tutor, this walk has something for everyone. This is the eleventh stop on the walk.
Author(s): No creator set

License information
Related content

Growing Graphene – Blue Sky Research Attempts To Replicate Nature
A truly ground-breaking experiment at The University of Nottingham could herald the creation of graphene and boron nitride layers in a controlled way at a scale never thought possible before. If successful this research could unlock the full potential of graphene in electronics and optoelectronics.
Author(s): No creator set

License information
Related content

Fundamentos de Gestión de Proyectos
Esta materia se dirige a estudiantes y graduados en ingenierías, ciencias sociales o disciplinas experimentales que estén llevando o vayan a llevar a cabo proyectos.
Author(s): Ángel Mena Nieto y Julio Terrados Cepeda

License information
Related content

Rights not set

This Week @Minnesota: Support the U Edition
This episode of This Week @Minnesota features the "Support the U Rally Day," which took place on Friday, March 30th, 2012.
Author(s): No creator set

License information
Related content

China From Past to Present: The Qing Dynasty
During the European period of colonization, China was
ruled by the Qing (or Manchu) dynasty and Hong Kong became a British
colony. This is a good video, but needs a map for students to follow the expansion and distances.

Author(s): No creator set

License information
Related content

Sand and the City - a floating beach for NYC?
Subscribe: http://smarturl.it/reuterssubscribe Why go to the beach, when it can come to you? A NY-based team launch a crowdfunding campaign for a floating beach on a repurposed barge in the Hudson River. Sharon Reich has more. More Innovations: http://smarturl.it/Innovations Subscribe: http://smarturl.it/reuterssubscribe Reuters tells the world's stories like no one else. As the largest international multimedia news provider, Reuters provides coverage around the globe and across topics includ
Author(s): No creator set

License information
Related content

Diabetic Dog Game
The Diabetic Dog educational game, with two related readings, are based on the 1923 Nobel Prize in Physiology or Medicine, which was awarded for discovering the hormone insulin, making it possible to treat people suffering from diabetes. In this game your dog has type 1 diabetes. This is a very serious disease. With proper treatment, however, your dog can live a happy life for many years. When we eat, the blood sugar level in our blood rises, and the hormone insulin is released into the blood st
Author(s): No creator set

License information
Related content

A Novel Method to Archive Plant Material for DNA Analysis
In this exercise, students isolate and analyze DNA from food plants in a supermarket, or from common backyard plants. Extracting plant DNA is often difficult using conventional means because undesirable material including PCR inhibitors often co-purifies with the DNA. The novel approach used in this exercise is simple and quick, and also avoids the use of dangerous organic reagents. Students crush plant material (spinach leaves in this exercise) onto special cards originally used to archive bloo
Author(s): No creator set

License information
Related content

Diffusion Across a Sheep Red Blood Cell Membrane
This cell membrane physiology laboratory uses sheep red blood cells to determine: (1) the isotonic and hemolytic molar concentrations of electrolytes and nonelectrolytes, and degree of electrolyte dissociation; (2) the diffusion rate of penetrating molecules of varying size and lipid solubility; and (3) the relationship of molecular size, number of hydroxyl groups, and partition coefficient to diffusion rate. Student research teams then design an experiment using the acquired techniques to deter
Author(s): No creator set

License information
Related content

8B. Anatomy of the Human Inguinal Area and Thigh
Science, medicine, biology, pubic tubercle, oblique, genitofemoral nerve, varicose veins, dorsal venous arch, calf, heel, foot, veins, blood supply, deep venous system, superficial venous system, fascia, femoral sheath, femoral artery, femoral vein, super
Author(s): No creator set

License information
Related content

1. Cell Biology, Embryology and Genetics (February 13, 2008)
Stem cell, medicine, health, disease, science, technology, research, clinical advances, controversy, ethics, law, society, politics, economics, social issue, religion, plasma, cytoplasm, nucleus, white blood cell, chromosome, gene expression, DNA, central
Author(s): No creator set

License information
Related content

2. Policy, Law and Society (February 20, 2008)
Stem cell, medicine, health, disease, science, technology, research, clinical advances, controversy, ethics, law, society, politics, economics, social issue, religion, plasma, cytoplasm, nucleus, white blood cell, chromosome, gene expression, DNA, central
Author(s): No creator set

License information
Related content

3. New Research Direction (February 27, 2008)
Stem cell, medicine, health, disease, science, technology, research, clinical advances, controversy, ethics, law, society, politics, economics, social issue, religion, plasma, cytoplasm, nucleus, white blood cell, chromosome, gene expression, DNA, central
Author(s): No creator set

License information
Related content

4. Towards the Clinic - Stem Cell (March 5, 2008)
Stem cell, medicine, health, disease, science, technology, research, clinical advances, controversy, ethics, law, society, politics, economics, social issue, religion, plasma, cytoplasm, nucleus, white blood cell, chromosome, gene expression, DNA, central
Author(s): No creator set

License information
Related content

5. The New Ethics of Stem Cell Research (March 12, 2008)
Stem cell, medicine, health, disease, science, technology, research, clinical advances, controversy, ethics, law, society, politics, economics, social issue, religion, plasma, cytoplasm, nucleus, white blood cell, chromosome, gene expression, DNA, central
Author(s): No creator set

License information
Related content

1. Cell Biology, Genetics, Embryology (June 25, 2007)
Stem cell, medicine, health, disease, science, technology, research, clinical advances, controversy, ethics, law, society, politics, economics, social issue, religion, plasma, cytoplasm, nucleus, white blood cell, chromosome, gene expression, DNA, central
Author(s): No creator set

License information
Related content

2. Five Important Research Advances (July 2, 2007)
Stem cell, medicine, health, disease, science, technology, research, clinical advances, controversy, ethics, law, society, politics, economics, social issue, religion, plasma, cytoplasm, nucleus, white blood cell, chromosome, gene expression, DNA, central
Author(s): No creator set

License information
Related content

3. Five Clinical Advances (July 9, 2007)
Stem cell, medicine, health, disease, science, technology, research, clinical advances, controversy, ethics, law, society, politics, economics, social issue, religion, plasma, cytoplasm, nucleus, white blood cell, chromosome, gene expression, DNA, central
Author(s): No creator set

License information
Related content