Cell Biology and Cancer
This curriculum supplement brings into the classroom new information about some of the exciting medical discoveries being made at the National Institutes of Health (NIH) and their effects on public health. This set is being distributed to teachers around the country free of charge by the NIH to improve science literacy and to foster student interest in science. The first three supplements in the series are designed for use in senior high school science classrooms: Emerging and Re-emerging Infect
Mitochondrial Control Region
Every human cell has a "second" genome, found in the cell's energy-generating organelle, the mitochondrion. In fact, each mitochondrion has several copies of its own genome, and there are several hundred to several thousand mitochondria per cell. This means that the mitochondrial (mt) genome is highly amplified. While each cell contains only two copies of a given nuclear gene (one on each of the paired chromosomes), there are thousands of copies of a given mt gene per cell. Because of this high
(Video) Nobel Lecture Series - Eric Accili.
Eric Accili, SFU kinesiology professor, on work of Rod MacKinnon who won the Nobel Prize for Chemistry for producing an image of cell membrane channels.
Assembly of Proteins in Membranes II from the course General Biochemistry and Molecular Biology
General Biochemistry and Molecular Biology - Fall 2006. This course covers molecular biology of prokaryotic and eukaryotic cells and their viruses. Mechanisms of DNA replication, transcription, translation. Structure of genes and chromosomes. Regulation of gene expression. Biochemical processes and principles in membrane structure and function, intracellular trafficking and subcellular compartmentation, cytoskeletal architecture, nucleocytoplasmic transport, signal transduction mechanisms, and c
7.340 Regenerative Medicine: from Bench to Bedside (MIT)
Regenerative medicine involves the repair and regeneration of tissues for therapeutic purposes, such as replacing bone marrow in leukemia, cartilage in osteoarthritis or cells of the heart after a heart attack. In this course, we will explore basic mechanisms of how cells differentiate into specific tissues in response to a variety of biologic signaling molecules. We will discuss the use of such factors for in vitro tissue production. We will also study the cellular mechanisms involved in the cl
5.3.1 Allosteric regulation
In this unit we explore how proteins are the 'doers' of the cell. They are huge in number and variety and diverse in structure and function, serving both the structural building blocks and the functional machinery of the cell. Just about every process in every cell requires specific proteins. The basic principles of protein structure and function which are reviewed in this unit are crucial to understanding how proteins perform their various roles.
Stem Cells: Programming and Personalized Medicine
After years of relentless lab work, rising and falling expectations, and the challenge of a sometimes hostile public, Rudolf Jaenisch says, “The scenario that looked like a fantasy … has come closer to reality. We can study complex human diseases in a Petri dish and potentially contribute to therapy.” In this l
5.2 All proteins bind other molecules
In this unit we explore how proteins are the 'doers' of the cell. They are huge in number and variety and diverse in structure and function, serving both the structural building blocks and the functional machinery of the cell. Just about every process in every cell requires specific proteins. The basic principles of protein structure and function which are reviewed in this unit are crucial to understanding how proteins perform their various roles.
Proteins
In this unit we explore how proteins are the 'doers' of the cell. They are huge in number and variety and diverse in structure and function, serving both the structural building blocks and the functional machinery of the cell. Just about every process in every cell requires specific proteins. The basic principles of protein structure and function which are reviewed in this unit are crucial to understanding how proteins perform their various roles.
Keynote Presentation: Academic Perspectives
Very simply stated, systems biology attempts to “capture the dynamic nature of living systems.” To accomplish this, says Hood, you “have to bring together the flavors of biology, chemistry, computer science, engineering and physics,” among others. It’s a vast area to tackle. But with tools like the internet and digital
Bioengineering at MIT: Building Bridges Between the Sciences, Engineering and Health Care (Part Two
Glycomics, the study of sugars’ role in living systems, is a relative newcomer to the revolution in molecular biology. In fact, Ram Sasisekharan remembers how colleagues told him “not to work on carbohydrates -- that it was useless.” But his research has shown that glycans, observed as long chains or intricat
Nanotechnology and the Study of Human Diseases
Subra Suresh fleshes out the promise of nanotechnology, at least in regard to our understanding of disease. His talk, which focuses on malaria and its impact on red blood cells, demonstrates how the fields of engineering, biology and medicine are converging.
To function properly, he explains, a red blood cel
Metastasis
No diagnosis of cancer is welcome, but some scenarios are more dreaded than others. Richard Hynes discusses what happens “when cells in the primary tumor lose their sense of address and wander off to places they’re not supposed to go.” His talk lays out the process of invasion, by which the cancer spreads into
Imperative of Science and Technology in Accelerating African and Rwandan Development
The news these days from Africa isn’t all bad. In fact, in some places, it’s downright hopeful, as Rwandan President Paul Kagame attests. “Our continent is no longer all about violence and disease and human disasters that scarred many African countries in recent decades,” says Kagame. “We are now becoming a continen
End of of unit questions
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Summary of Section 8
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
7.3 The eukaryotic chromosome (continued)
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Acknowledgements
In this unit we explore how proteins are the 'doers' of the cell. They are huge in number and variety and diverse in structure and function, serving both the structural building blocks and the functional machinery of the cell. Just about every process in every cell requires specific proteins. The basic principles of protein structure and function which are reviewed in this unit are crucial to understanding how proteins perform their various roles.
7.3 The eukaryotic chromosome
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
7.1 Introduction
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
