In this unit we explore how proteins are the 'doers' of the cell. They are huge in number and variety and diverse in structure and function, serving both the structural building blocks and the functional machinery of the cell. Just about every process in every cell requires specific proteins. The basic principles of protein structure and function which are reviewed in this unit are crucial to understanding how proteins perform their various roles.
Education in the wild: contextual and location-based mobile learning in action. A report from the ST
A new report has been published by the LSRI/University of Nottingham that gives an essential overview of research into location-based contextual mobile learning primarily across Europe, edited by Elizabeth Brown. The report follows on from a 2-day workshop funded by the STELLAR Network of Excellence as part of their 2009 Alpine Rendez-Vous workshop series. Contributors have provided examples of innovative and exciting research projects and practical applications for mobile learning in a location
7.90J Computational Functional Genomics (MIT)
The course focuses on casting contemporary problems in systems biology and functional genomics in computational terms and providing appropriate tools and methods to solve them. Topics include genome structure and function, transcriptional regulation, and stem cell biology in particular; measurement technologies such as microarrays (expression, protein-DNA interactions, chromatin structure); statistical data analysis, predictive and causal inference, and experiment design. The emphasis is on coup
Chemical and Environmental Behaviour of Materials: Batteries
This animation demonstrates electron flow in a Daniell cell. From TLP: Batteries
HST.721 The Peripheral Auditory System (MIT)
In this course, experimental approaches to the study of hearing and deafness are presented through lectures, laboratory exercises and discussions of the primary literature on the auditory periphery. Topics include inner-ear development, functional anatomy of the inner ear, cochlear mechanics and micromechanics, mechano-electric transduction by hair cells, outer hair cells' electromotility and the cochlear amplifier, otoacoustic emissions, synaptic transmission, stimulus coding in auditory nerve
Construction d'une base de connaissances et d'une banque de ressources pour le domaine du téléappr
This article sets the foundation for the development of a knowledge base and a resource (learning object) repository in the domain of telelearning, enabling researchers to reference resources in this domain using standard specifications based on domain ontology and to integrate them according to a set of research or teaching activities. The resources are referenced with metadata based on domain ontology and their search is guided by use cases describing activities where these resources are used
In this hands-on activity, students build their own two-cell battery. They also determine which electrolyte solution is best suited for making a battery.
A chapter which describes the mechanisms of signal transduction in a eukaryotic cell, including the activation of G-proteins and kinase cascades (49 figures). The unit is intended as ~10hrs study at level 2/3. It also provides background reading for the experimental investigation 'Investigating intracellular signalling pathways' (http://open.jorum.ac.uk/xmlui/handle/123456789/1581).
Introduction to Glycolysis
Living cells can process certain sugar molecules, rearranging their atoms and this process can supply energy to the cell to power growth and other functions. This process is called glycolysis. Glycolysis evolved billions of years ago when there was no oxygen in the earth's atmosphere and it was therefore impossible for cells to gain energy from the oxidation of sugar molecules using oxygen. Later when oxygen was produced as a byproduct of photosynthesis cells evolved to utilise oxygen to oxidise
7.342 Cancer Biology: From Basic Research to the Clinic (MIT)
This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. In 1971, President Nixon declared the "War on Cancer," but after three decades the war is still raging. How much progress have we made toward winning the war and what are we doing to improve the fight? Unde
Open-celled aluminium foam
Although the processing route is complicated and the product expensive, there is a high degree of control over the cell structure of such foams and the final shape can be controlled to meet near-net-shape requirements.
9.011 The Brain and Cognitive Sciences I (MIT)
Survey of principles underlying the structure and function of the nervous system, integrating molecular, cellular, and systems approaches. Topics: development of the nervous system and its connections, cell biology or neurons, neurotransmitters and synaptic transmission, sensory systems of the brain, the neuro-endocrine system, the motor system, higher cortical functions, behavioral and cellular analyses of learning and memory. First half of an intensive two-term survey of brain and behavioral s
Virtual yeast cell
This rich learning object is used to introduce yeast cytology to students taking Module D24BS3 Brewery Yeast Management as part of the MSc in Brewing Science. The virtual cell permits the students to understand structure and function of yeast organelles.
FOAMCARP closed cell aluminium foam
Additions such as SiC are made to molten aluminium or aluminium alloy to modify the melt viscosity and make it suitable for foaming. Calcium carbonate is then added to the melt which is solidified to form a precursor which can be foamed in a controlled manner by a subsequent heat treatment. The resulting foam has a fine and relatively uniform cell structure.
High magnification SEM image of open cell polyurethane foam
If a gas is injected into a liquid it forms a cellular foam structure. When a thermoset prepolymer of low viscosity is foamed, the polymer can drain from the cell walls (driven by surface tension) before it sets at the cell edges, leaving an open-celled foam. The cell edges have three concave sides, and some remnants of collapsed cell walls can be seen at the cell edges.
FORMGRIP closed cell aluminium foam
Additions such as SiC are made to molten aluminium or aluminium alloy to modify the melt viscosity and make it suitable for foaming. 1 to 3 wt% of pre-oxidised titanium hydride is then added to the melt which is solidified to form a precursor which can be foamed in a controlled manner by a subsequent heat treatment. The resulting foam has a relatively fine and uniform cell structure.
9.18 Developmental Neurobiology (MIT)
This course considers molecular control of neural specification, formation of neuronal connections, construction of neural systems, and the contributions of experience to shaping brain structure and function. Topics include: neural induction and pattern formation, cell lineage and fate determination, neuronal migration, axon guidance, synapse formation and stabilization, activity-dependent development and critical periods, development of behavior.
HST.535 Principles and Practice of Tissue Engineering (MIT)
The principles and practice of tissue engineering (and regenerative medicine) are taught by faculty of the Harvard-MIT Division of Health Sciences and Technology (HST) and Tsinghua University, Beijing, China. The principles underlying strategies for employing selected cells, biomaterial scaffolds, soluble regulators or their genes, and mechanical loading and culture conditions, for the regeneration of tissues and organs in vitro and in vivo are addressed. Differentiated cell types and stem cells
Model of the monoclinic ZrO2 unit cell
Rotating model of the monoclinic ZrO2 unit cell.
Orchestrating cell separation in plants : what are the risks and benefits?
In this podcast, Professor Roberts from the School of Biosciences discusses his research into the mechanism responsible for regulating cell separation in plants. In particular how plants ‘shed’ parts of themselves such as leaves or fruit. Professor Roberts explores the potential application of his research, through prevention or encouraging of the ‘shedding’ process, agricultural harvests could potentially be increased or even synchronised. Professor Roberts also discusses the resistance