Dynamic Remodeling of Individual Nucleosomes Across a Eukaryotic Genome in Response to Transcription
The eukaryotic genome is packaged as chromatin with nucleosomes comprising its basic structural unit, but the detailed structure of chromatin and its dynamic remodeling in terms of individual nucleosome positions has not been completely defined experimentally for any genome. We used ultra-high–throughput sequencing to map the remodeling of individual nucleosomes throughout the yeast genome before and after a physiological perturbation that causes genome-wide transcriptional changes. Nearly 80%
Eye on Einstein
This OLogy activity challenges students to find nine inventions that Einstein's ideas helped to create. The activity begins with an illustration of Al's Junk Shop. Mixed in with his junk are a Global Positioning System, CD player, computer, calculator, scanner, laser pointer, TV, and representations of both laser surgery and nuclear energy. After making a mental list of their nine choices, students can click to a second page to check their answers. Each invention has a rollover note about how Ei
General View of Ave Maria Grotto, Cullman, Alabama
This image is part of a series of color photographs of the Ave Maria Grotto in Cullman, Alabama. Postcard text: (back) General view of Ave Maria Grotto, Cullman, Alabama. The AVE MARIA GROTTO consists of over 125 miniature reproductions of famous churches, shrines and buildings from all over the world. Encompassing an area of over three acres, this miniature fairyland was built by a Benedictine Monk, Brother Joseph. He has spent over 40 years in making this scenic spot, using all kinds of jewe
This NASA site explains the three major types of atmospheric aerosols - volcanic emissions, desert dust, and anthropogenic aerosols - and how they affect global climate. The site discusses the generation and atmospheric distribution of these aerosols, as well as the chemical and physical processes by which they create global cooling.
This site features Java Applet, QuickTime, and Flash animations that illustrate characteristics and functions of the atmosphere. They show how atmospheric temperature, pressure, and density change with respect to changing altitude, the way different kinds of radiation (x-ray, ultraviolet, visible, and infrared) act in various levels of the atmosphere (troposphere, stratosphere, mesosphere, and thermosphere/ionosphere), how oxygen gas and chlorofluorocarbons (CFCs) interact with ultraviolet radia
Hopewell Furnace: A Pennsylvania Iron-making Plantation
This site tells the story of one of the 65 small ironworks operating in southeast Pennsylvania during the American Revolution. The Hopewell Furnace, located in forested hills and valleys along French Creek in Berks County, operated from 1771 to 1883. The furnace was the center of a self-contained hierarchical community of 200-300 people, all of whose work was related to the production of iron.
Stereotypes of the French
This unit comprises four major lessons which are distinct yet cumulative. In the first lesson, the students will lay the groundwork for their examination of French stereotypes by generating those stereotypes themselves. They may draw, write, or find examples of what they think are "typical" French things. In the second lesson, they will be required to change perspective -- instead of being the examiners, they will be the examined culture. Students will look at various examples of stereotypes of
Celebrate Hispanic American Month
highlights publications, properties listed in the National Register, and National Parks related to the creativity, culture, and political experiences of Hispanic Americans.
Based on UNICEF's annual flagship publication, The State of the World's Children report (SOWC), the U.S. Fund for UNICEF has developed and released these free resources for educators to use with students in grades 3-12. The lesson plans and resources in these units are designed to be used sequentially or separately. Topics include addressing global affairs issues such as the Millennium Development Goals, real life stories from youth, the causes of childhood exclusion, and water and sanitation.
Master Teachers: Ali Akbar Khan
SPARK visits Ali Akbar Khan, one of the finest musicians of North India in the world as he passes his gift to several generations of musicians at the Ali Akbar Khan College of Music in San Rafael, California. This Educator Guide offers explorations of North Indian Classical Music and culture.
The aim of this lesson is to help students identify their personal learning styles so they can study and learn more effectively. It is the ninth lesson in the study skills series and it introduces adult learners to the concept of learning styles. Students will have an opportunity to reflect on different ways of learning and to validate different abilities and capabilities, both their own and those of others. The lessons are designed as a package with key skills reinforced in each subsequent less
The aim of this lesson is to help students acquire skills that help them prepare for examinations in a focused and organized way. Students devise strategies for reviewing material and developing a revision timeline, and learn to identify the areas of study on which they should concentrate to prepare for tests. They review helpful tips and learn to use past examinations as a guide for future ones. It is the seventh lesson in the study skills series and is intended to support adult learners who ar
Artist in Search of a Medium: Jonathon Keats
SPARK trails writer, critic, and Conceptual artist Jonathon Keats as he works on his project, Divine Taxonomy, which attempts to find God's place on the phylogenetic tree. This Educator Guide explores the history of Conceptual art and the role of science in contemporary art.
The aim of this lesson is to enable students to take control of their learning in a positive way. It is the third lesson in the study skills series and is intended to support adult learners who are embarking on a course of study and need to acquire skills which will help them to be successful. The lessons are designed as a package with key skills reinforced in each subsequent lesson so that a study culture is developed over time. They can be delivered sequentially or used individually, as a whol
George Washington: First in War, First in Peace, and First in the Hearts of His Countrymen
This site consists of three lessons examining George Washington's leadership in the French and Indian War, at the Federal Convention, and as chief executive. They are based on primary source documents from the George Washington Papers, 1741-1799. The lessons are intended for secondary students, grades 8-12. The documents from Washington's Letterbooks include focus questions that may be used in Socratic seminars and in cooperative learning groups.
Edward S. Curtis's The North American Indian: Photographic Images
This is one of the most significant and controversial representations of American Indian culture ever produced. Issued in a limited edition from 1907-1930, the publication continues to influence the image of Indians in popular culture. In over 2000 photos and narrative, Curtis portrayed the traditional customs and lifeways of 80 Indian tribes.
American Landscape and Architectural Design, 1850-1920
This collection of approximately 2,800 lantern slides represents an historical view of American buildings and landscapes built during the period 1850-1920. It represents the work of Harvard faculty, such as Frederick Law Olmsted Jr., Bremer W. Pond, and James Sturgis Pray, as well as that of prominent landscape architects throughout the country. The collection offers views of cities, specific buildings, parks, estates and gardens, including a complete history of Boston's Park System. In addition
American Indians of the Pacific Northwest
This digital collection integrates over 2,300 photographs and 7,700 pages of text relating to the American Indians in two cultural areas of the Pacific Northwest, the Northwest Coast and Plateau. These resources illustrate many aspects of life and work, including housing, clothing, crafts, transportation, education, and employment. The materials are drawn from the extensive collections of the University of Washington Libraries, the Northwest Museum of Arts & Culture (formerly the Cheney Cowles M
African American Perspectives: Pamphlets from the Daniel A. P. Murray Collection, 1818-1907
This site presents a review of African-American history and culture as seen through the practice of pamphleteering. The site includes sermons on racial pride and essays on segregation, voting rights, and violence against African-Americans.
Global education as good pedagogy
A wide variety of teaching strategies and resources pass under the name of global education. This article provides strategies for evaluating global education and ensuring that it focuses on students' academic success.