2012 Nobel Lecture in Literature by Mo Yan
Mo Yan delivered his Nobel Lecture on 7 December 2012, at the Swedish Academy, Stockholm. He was introduced by Kjell Espmark, member of the Nobel Committee for Literature. The lecture was delivered in Chinese. To read the text version of the lecture, see: http://www.nobelprize.org/nobel_prizes/literature/laureates/2012/yan-lecture.html
Lesson 03 - One Minute Luxembourgish
In lesson 03 of One Minute Luxembourgish you will learn to say that you can speak a little Luxembourgish. Remember - even a few phrases of a language can help you make friends and enjoy travel more. Find out more about One Minute Languages at our website - http://www.oneminutelanguages.com. One Minute Luxembourgish is brought to you by the Radio Lingua Network and is ©Copyright 2008.Author(s):
Reuters Today: HSBC to pay biggest ever bank fine
Dec. 11 - HSBC has agreed to pay $1.92 billion to settle a U.S. criminal probe into money-laundering -- the largest penalty ever paid by a bank.
The Rotating Dynamic Architecture Building in Dubai The Da Vinci Tower is a proposed 313 m (1,027 ft) high, 68-floor tower in Dubai, United Arab Emirates, and will be the first ever "building in motion".
Onderwijs door de jaren Veranderingen in het onderwijs
Wealth Strategies: Fiscal Cliff a piece of fiction - Kotok
Dec. 12 - Cumberland Advisors' David Kotok says concern over the looming fiscal cliff is unwarranted and says the U.S. stock market is poised for a multi-year run.
UK Minister on latest unemployment figures
Dec. 12 - Minister for Employment, Mark Hoban, gives his outlook for the UK jobs market and reaction to the latest figures.
Aptamers Aptamers are nucleic acid molecules that have been developed to mimic the selective and tight binding of other molecules such as antibodies. In order to identify an aptamer that is capable of binding to a target molecule, a process called Selex (systematic evolution of ligands by exponential enrichment) is utilised. The strategy relies upon a combination of a selective binding assay and amplification by PCR. A ‘library’ of short single-stranded DNA oligonucleotides is synthesised <
2.1.1 Ron revisited In Case Report 1 you met Ron. Ron is 59 years old, has a BMI of 31 and a central obesity ratio of 0.96, indicating that he is moderately obese, with the fat concentrated in his abdomen, rather than his hips. Clearly a number of factors, some environmental, others relating to Ron's age and all interacting with Ron's genetic constitution, may help to provide an explanation. Let's look at some of these factors in a little more detail. It is clear that Ron enjoys a comfortable lifestyle with litt
3 Sources of energy from the natural environment The natural environment itself is bathed in energy from other sources. Standing on a cliff top on a bright spring day you can feel the warmth of the Sun and the freshness of the breeze and hear the crashing of breaking waves below. All these energetic processes can be compared in terms of Author(s):
2.2 Present-day energy use Global annual consumption of all forms of primary energy increased more than tenfold during the 20th century (Author(s):
Introduction In recent years, scientists have made huge gains in their understanding of how genes can be altered and transferred from one organism to another – but that knowledge has been acquired amidst controversy and concern. The deep ethical concerns that have resulted from the emergence of genetic manipulation are explored in this unit. We begin with an examination of the basic structure and function of genes. A number of pioneering examples and techniques are explored, helping to explain why our p
3.3 Summary of Section 3
E. coli has a remarkable method of obtaining iron from its environment, which involves the use of very powerful iron chelators, called siderophores. One siderophore in particular, enterobactin, forms an extremely stable complex with iron(III). The high stability of this complex is due partly to the rigid, preorganised structure of the ligand, and partly to the iron(III) being the correct size and charge to be chelat
3.6.1 Identifying the pregnacy Our description of the developing embryo has, so to speak, detached it from its mother. But we should remember that on the other end of the placenta is a woman whose reaction to her pregnancy may lie almost anywhere in the scale of human emotion, and whose behaviour during her pregnancy will have an enormous effect on its outcome. This section attempts to look at the pregnancy from the mother's point of view. Of course, it cannot possibly be applicable to all women in all pregna
4.2 The reduction of chromosome number: meiosis If you look at the chromosomes shown in Figure 8 you will see that they have been lined up in pairs. The members of each pair are of similar shape and size, and unlike the members of other pairs. At a molecular level these distinctions are maintained: the order of the bases in the DNA is very similar in both members of a pair, but is quite different from that found in other pairs. By ‘very similar’ we mean that the order of the particular genes on each chromosome of the pair is the same,
4.5 Geological criteria for safe radioactive waste disposal Even in the best of circumstances, containers such as the one shown in Figure 19 will survive for only 100–1000 years, although the glass itself may inhibit the migration of radioactive isotopes for a further 1000 years. So, in view of the long decay times (Author(s):
4.4 Radioactive waste disposal Most fission products from nuclear reactors are solid at ordinary temperatures. They cluster around atomic mass numbers 90 and 140 (see, for example, Equation 2). From the point of view of waste disposal, the problem is that most of them are highly radioactive. The common radioactive isotopes produced in nuclea
1 Natural groups Darwin made extensive observations on a great many creatures, including mammals, and noticed that species fell into natural groups, e.g. lions, tigers and leopards have many similarities, and resemble cats. On the basis of his observations, he was able to place mammals in distinct groups. His work has continued, and we now recognise that mammals have evolved from a common ancestor, and have branched into many different groups, or ‘Orders’. The animation below shows the different O
7.3 Regulation of secretion Up to this point we have made a clear distinction between constitutive secretion and regulated secretion. In reality however the border is a bit more blurred. For example, many molecules are constitutively expressed on the surface of a cell, but their expression is increased in response to a particular stimulus. In other words, surface expression is determined by both constitutive and regulated secretion. Constitutive secretion is regulated primarily at the level of protein synthesis, whereas
2.5 The endocytic pathways and lysosomes Endocytosis is the process by which cells internalise molecules from the outside, and it includes pinocytosis, the uptake of small soluble molecules in vesicles, and phagocytosis, the internalisation of large insoluble particles. These are two ends of a spectrum as seen microscopically, but the receptors, the subsequent intracellular trafficking pathways and the fate of the internalised molecules, vary depending on the cell type and its functions. The endocytic pathway co
