Human Genome Education
Anyone with a computer and an Internet connection can now explore the draft sequence of the human genome. How can molecular biologists capitalize on these data riches, and what are the advantages of using the assembled draft sequence? This website aims to jump-start those who want make use of this information, but are not sure where or how to start.
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Bad blood - A case study of the Tuskegee syphilis project
Syphilis is a venereal disease spread during sexual intercourse. It can also be passed from mother to child during pregnancy. It is caused by a corkscrew-shaped bacterium called a spirochete, Treponema pallidum. This microscopic organism resides in many organs of the body but causes sores or ulcers (called chancres) to appear on the skin of the penis, vagina, mouth, and occasionally in the rectum, or on the tongue, lips, or breast. During sex the bacteria leave the sores of one person and enter
Author(s): Fourtner, A.W.,Fourtner, C.F.,Herreid, C.F.

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Reading for Philosophical Inquiry
In this introduction to philosophical thinking, we will read some essays specially chosen from four main areas of interest: (1) the philosophy of life, (2) the philosophy of religion, (3) ethics, and (4) metaphysics and theory of knowledge. Although our approach is not comprehensive, it is reasonably representative of some of the more significant areas of philosophical inquiry. The readings are intended to illustrate the interrelations between these subject areas of philosophy and, as well, to p
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7.340 Regenerative Medicine: from Bench to Bedside (MIT)
Regenerative medicine involves the repair and regeneration of tissues for therapeutic purposes, such as replacing bone marrow in leukemia, cartilage in osteoarthritis or cells of the heart after a heart attack. In this course, we will explore basic mechanisms of how cells differentiate into specific tissues in response to a variety of biologic signaling molecules. We will discuss the use of such factors for in vitro tissue production. We will also study the cellular mechanisms involved in the cl
Author(s): Petra Simic

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7.345 Vascular Development in Life, Disease and Cancer Medicine (MIT)
The growth of blood vessels, a process known as angiogenesis, is one of the earliest events in mammalian development and is regulated by a sensitive interplay of growth factors and other molecules. In this course, we will discuss the key molecular regulators of blood vessel development as well as the techniques and experimental systems that have been utilized by vascular biologists. We will also examine the success of several anti-angiogenic treatments that have been approved by the Food and Dru
Author(s): Naba, Alexandra,Turner, Christopher

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5.111 Principles of Chemical Science (MIT)
Introduction to chemistry, with emphasis on basic principles of atomic and molecular electronic structure, thermodynamics, acid-base and redox equilibria, chemical kinetics, and catalysis. Introduction to the chemistry of biological, inorganic, and organic molecules.
Author(s): Ceyer, Sylvia Teresse,Drennan, Catherine L.

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Stem Cells: Programming and Personalized Medicine
After years of relentless lab work, rising and falling expectations, and the challenge of a sometimes hostile public, Rudolf Jaenisch says, “The scenario that looked like a fantasy … has come closer to reality. We can study complex human diseases in a Petri dish and potentially contribute to therapy.” In this l
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An introduction to biological systematics
This unit is concerned with macroevolution – the patterns and processes of evolution above the species level. A crucial consideration in macroevolutionary studies is that of the evolutionary relationships (phylogeny) of the organisms in question. The unit begins with an introduction to the scope of macroevolutionary studies and illustrates methods of reconstructing phylogeny, from both morphological and molecular data.
Author(s): The Open University

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Bioengineering at MIT: Building Bridges Between the Sciences, Engineering and Health Care (Part Two
Glycomics, the study of sugars’ role in living systems, is a relative newcomer to the revolution in molecular biology. In fact, Ram Sasisekharan remembers how colleagues told him “not to work on carbohydrates -- that it was useless.” But his research has shown that glycans, observed as long chains or intricat
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Nanotechnology and the Study of Human Diseases
Subra Suresh fleshes out the promise of nanotechnology, at least in regard to our understanding of disease. His talk, which focuses on malaria and its impact on red blood cells, demonstrates how the fields of engineering, biology and medicine are converging.

To function properly, he explains, a red blood cel

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Biological Large Scale Integration
Though Stephen Quake’s research is confined to the smallest of scales, his achievements have already made a large impact on the study of biology. Quake’s area of microfluidics involves fabricating tiny devices akin to those a plumber uses, but useful on the molecular level. Quake modestly describes his “plumbing
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Dendrite Morphogenesis and Channel Regulation: Implications for Mental Health and Neurological Disor
Lily and Yuh-Nung Jan have been pioneers in the field of molecular neurobiology for more than 30 years, and their genetic studies of fruit flies and mice have provided major insights into many different aspects of brain function and development. In this joint lecture, they summarize their recent work on the genetic control of
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End of of unit questions
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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Summary of Section 8
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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7.3 The eukaryotic chromosome (continued)
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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7.3 The eukaryotic chromosome
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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7.1 Introduction
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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Summary of Section 6
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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6.5 Conformational changes upon protein–DNA interactions
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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Acknowledgements
This Unit studies 'proteins'. Starting with a simple analysis of the molecular make up, the Unit moves on to look at the importance of protein and how they are digested and absorbed
Author(s): The Open University

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