5.111 Principles of Chemical Science (MIT)
Introduction to chemistry, with emphasis on basic principles of atomic and molecular electronic structure, thermodynamics, acid-base and redox equilibria, chemical kinetics, and catalysis. Introduction to the chemistry of biological, inorganic, and organic molecules.
Author(s): Ceyer, Sylvia Teresse,Drennan, Catherine L.

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Stem Cells: Programming and Personalized Medicine
After years of relentless lab work, rising and falling expectations, and the challenge of a sometimes hostile public, Rudolf Jaenisch says, “The scenario that looked like a fantasy … has come closer to reality. We can study complex human diseases in a Petri dish and potentially contribute to therapy.” In this l
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An introduction to biological systematics
This unit is concerned with macroevolution – the patterns and processes of evolution above the species level. A crucial consideration in macroevolutionary studies is that of the evolutionary relationships (phylogeny) of the organisms in question. The unit begins with an introduction to the scope of macroevolutionary studies and illustrates methods of reconstructing phylogeny, from both morphological and molecular data.
Author(s): The Open University

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Bioengineering at MIT: Building Bridges Between the Sciences, Engineering and Health Care (Part Two
Glycomics, the study of sugars’ role in living systems, is a relative newcomer to the revolution in molecular biology. In fact, Ram Sasisekharan remembers how colleagues told him “not to work on carbohydrates -- that it was useless.” But his research has shown that glycans, observed as long chains or intricat
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Nanotechnology and the Study of Human Diseases
Subra Suresh fleshes out the promise of nanotechnology, at least in regard to our understanding of disease. His talk, which focuses on malaria and its impact on red blood cells, demonstrates how the fields of engineering, biology and medicine are converging.

To function properly, he explains, a red blood cel

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Biological Large Scale Integration
Though Stephen Quake’s research is confined to the smallest of scales, his achievements have already made a large impact on the study of biology. Quake’s area of microfluidics involves fabricating tiny devices akin to those a plumber uses, but useful on the molecular level. Quake modestly describes his “plumbing
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Dendrite Morphogenesis and Channel Regulation: Implications for Mental Health and Neurological Disor
Lily and Yuh-Nung Jan have been pioneers in the field of molecular neurobiology for more than 30 years, and their genetic studies of fruit flies and mice have provided major insights into many different aspects of brain function and development. In this joint lecture, they summarize their recent work on the genetic control of
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End of of unit questions
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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Summary of Section 8
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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7.3 The eukaryotic chromosome (continued)
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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7.3 The eukaryotic chromosome
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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7.1 Introduction
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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Summary of Section 6
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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6.5 Conformational changes upon protein–DNA interactions
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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Acknowledgements
This Unit studies 'proteins'. Starting with a simple analysis of the molecular make up, the Unit moves on to look at the importance of protein and how they are digested and absorbed
Author(s): The Open University

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The Power of Basic Science Applied to Medical Progress: Past Examples and Hope for Schizophrenia and
An exemplar of the purpose-driven life in medical science, Ed Scolnick details research milestones from a remarkably varied career, revealing how scientific insight and collaborative effort translate into life-saving solutions for millions.

This physician turned biochemist has held distinguished positions at t

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Human Rights & the US State Department
Ambassador Shattuck provides insights from his experiences as Assistant Secretary of State for Human Rights in the Clinton Administration. Highlights include his analysis of the global events in the post-Cold War period which he states foreshadowed the attacks of September 11th . He defines two competing forces, the forces of integration, (
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Technology and the Future Warrior: Protecting Soldiers in the 21st Century
The Super Soldier has one foot out of the lab, and will be reporting for battle by 2020. “Dutch” DeGay’s Army researchers have begun to “rebuild the soldier from the skin out.” Current infantrymen, stationed in Iraq and Afghanistan, must shoot, move and communicate carrying upwards of 100 pounds of personal armor an
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Pursuing The Endless Frontier: Essays on MIT and the Role of Research Universities
At the conclusion of 14 years at the helm of the Institute, Chuck Vest discusses the challenges and opportunities involved in guiding a major research university through tumultuous times. Vest’s new book, outlined in his remarks, provides a detailed and intimate view of his MIT “adventure.” Some key chapters: At the start of hi
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Spherulite in poly-3-hydroxy butyrate (PHB)
Polymer melts often crystallise from heterogeneous nuclei to form ribbon-like lamellae, which have a folded chain molecular structure. They commonly radiate outwards from the nucleation point, to form spherical features called spherulites - which are often quite large. The characteristic Maltese cross pattern, seen when viewed between crossed polars, results from isoclinic fringes formed when one of the principal vibration directions is approximately parallel to the polariser. In some cases
Author(s): DoITPoMS, University of Cambridge,Prof T W Clyne,

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