7.340 Under the Radar Screen: How Bugs Trick Our Immune Defenses (MIT)
In this course, we will explore the specific ways by which microbes defeat our immune system and the molecular mechanisms that are under attack (phagocytosis, the ubiquitin/proteasome pathway, MHC I/II antigen presentation). Through our discussion and dissection of the primary research literature, we will explore aspects of host-pathogen interactions. We will particularly emphasize the experimental techniques used in the field and how to read and understand research data. Technological advances
Author(s): Grotenbreg, Gijsbert,Paquet, Marie-Eve

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7.342 G-Protein Coupled Receptors: Vision and Disease (MIT)
How do we communicate with the outside world? How are our senses of vision, smell, taste and pain controlled at the cellular and molecular levels? What causes medical conditions like allergies, hypertension, depression, obesity and various central nervous system disorders? G-protein coupled receptors (GPCRs) provide a major part of the answer to all of these questions. GPCRs constitute the largest family of cell-surface receptors and in humans are encoded by more than 1,000 genes. GPCRs convert
Author(s): Kota, Parvathi

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2.797J Molecular, Cellular, and Tissue Biomechanics (MIT)
This course develops and applies scaling laws and the methods of continuum mechanics to biomechanical phenomena over a range of length scales. Topics include structure of tissues and the molecular basis for macroscopic properties; chemical and electrical effects on mechanical behavior; cell mechanics, motility and adhesion; biomembranes; biomolecular mechanics and molecular motors. The class also examines experimental methods for probing structures at the tissue, cellular, and molecular levels.
Author(s): Lang, Matthew,Kamm, Roger D.

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Vegetable MD online

thumbnailPublished on the Web by the Cornell Plant Pathology Department, this site provides access to a range of fact sheets on vegetable diseases. The fact sheets are listed by crop and cover a range of issues, including production costs, varie
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5.13 Organic Chemistry II (MIT)
This intermediate organic chemistry course focuses on the methods used to identify the structure of organic molecules, advanced principles of organic stereochemistry, organic reaction mechanisms, and methods used for the synthesis of organic compounds. Additional special topics include illustrating the role of organic chemistry in biology, medicine, and industry.
Author(s): Berkowski, Kimberly,Jamison, Timothy F.

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Distinguished Innovator Lecture Series: John Steuart
Distinguished Innovator Lecture Series John Steuart, Managing Director, Claremont Creek Ventures John Steuart is a Managing Director of Claremont Creek Ventures, an Oakland-based venture capital firm investing in early-stage information technology companies. John focuses on the intersection of the information technology and life sciences markets including bioinformatics, molecular diagnostics, genomics, proteomics, software and instrumentation for med-tech industries. John serves on the board
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Media, McClellan and the War.
Bill Moyers on the Democratic Party and its new nominee. Plus, there's nothing new in Scott McClellan's book about the propaganda campaign or the role of the press in selling the war, so why is it such big news? Journalists Jonathan landay and John Walcott of McClatchy newspapers and Greg Mitchell of EDITOR AND PUBlISHER analyze the reaction of the administration and the media to McClellan's book. And, the Annenberg School's Kathleen Hall Jamieson and Dr. Ronald Walters, director of the African
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Amplification of Biochemical Signals: the ELISA Test
Students are introduced to the role of molecular shape, weak attractions and charge in biology and biochemistry, and then undertake a simulated Direct ELISA test.
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BioGrapher
PURPOSE: A simple Excel-based workbook with worksheets as a front end for the AT&T GraphViz Graph Layout software suite. BioGrapher enhances Excel-based tools developed in the Chemistry and Biology Departments at Beloit College to allow for convenient visualization of graphs and graphical connections that are important in systems and computational biology, molecular biology, biochemistry, and genetics.
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Case It
This software can be used to investigate common molecular biology laboratory procedures using DNA or protein sequence data. These simulations and cases are based primarily on genetic and infectious disease with techniques such as: DNA electrophoresis, Southern blot, PCR, Multiplex PCR, Dot blot, ELISA, Western blot, 96-well PCR, protein electrophoresis. Case It! is collaborative BioQUEST project between the University of Wisconsin-River Falls and Michigan State University.
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NOP - Sustainable organic teaching lab
Sustainable development needs chemical research Research and innovation are preconditions for the transformation of economic and social processes in favor of a sustainable development. Chemistry, the science and practice of the transformation of matter, is of central importance. Everyone dealing with chemistry can contribute substantially to sustainable development and holds special responsibility. Already in education the links between reactions and substances with the consumption of energy and
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Get This Bug Off Me!
It's a natural reaction to be frightened of some insects. Many insects have the ability to harm people, and many insects look very menacing. However, many large insects are not harmful at all. Because it would take several volumes to describe every insect, this publication is intended to distinguish several common insects and insect relatives in Kentucky that are or are not harmful.
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A Manual of Online Molecular Biology Techniques
This is a collection of tried-and-true technique descriptions used in teaching postgraduate students in the Department of Molecular & Cell Biology at UCT.
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Genetics
Medical genetics involves the application of genetic principles in the practice of medicine. The material in this course encompasses diagnosis and treatment of genetic diseases (such as cancer genetics ), study of inheritance of diseases in families, mapping of disease genes to their chromosome locations, study of the molecular genetics and pathogenesis of inherited disorders, provision of genetic counseling for families, and investigations of methods for gene therapy. Unlike any other field, ge
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Renal Pathophysiology
The importance of the kidneys is most clearly demonstrated in the presence of pathophysiologic states. The kidneys play a central role in the maintenance of the internal milieu by balancing fluid, electrolytes, and hydrogen ions to provide optimal conditions for molecular, cellular, and body system function. They also serve as the major excretory organ for metabolic byproducts, drugs, and other organic substances. Finally, the kidneys are an important endocrine organ, producing vasoactive factor
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Calculating Molecular Weight
The molecular weight is the mass of one mole of a substance. Usually, the units used for this are grams per mole. In this movie, we show how to calculate the molecular weight of a substance from the atomic weights given on the periodic table. On another page, we use the molecular weight to convert between the macroscopic scale (grams of a substance) and the microscopic scale (number of molecules of that substance).
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Finding the Empirical Formula from a Molecular Formula
Elemental analysis is a useful qualitative analysis technique since it allows us to check if a sample is consistent with a given molecular formula. For instance, suppose we believe our sample is benzene (C6H6). We can compare the following:The empirical formula (CH) obtained from the molecular formula of benzene (C6H6); The empirical formula obtained from a elemental analysis of the sample. If the two empirical formulae do not agree, then the sample is not benzene. If the formulae agree, then ou
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Finding Empirical Formula from an Elementary Analysis
On another page, we discuss how to obtain the empirical formula from a given molecular formula. Here, we consider how to obtain the empirical formula from an elemental analysis of a sample. Remember that comparing the empirical formula obtained from an elemental analysis with that from a molecular formula tells us if the sample is consistent with the molecular formula.
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Limiting Reagents
We are now ready to pull everything we know about reaction stoichiometry together, and answer the question: Given some initial amount of reactants, what should be present after a chemical reaction goes to completion? The procedure for answering this question is often called the "limiting reagent problem." You'll see why this name is appropriate in the following video.
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Meals-Ready-To-Eat Scenario
You and a friend are hiking the Appalachian Trail when a storm comes through. You stop to eat, but find that all available firewood is too wet to start a fire. From your Chem 106 class, you remember that heat is given off by some chemical reactions; if you could mix two solutions together to produce an exothermic reaction, you might be able to cook the food you brought along for the hike. Luckily, being the dedicated chemist that you are, you never go anywhere without taking along a couple chemi
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