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7.2 Information sources

7.2.1 How do I find the information required to carry out COSHH risk assessments?

The best source of information is the material safety data sheet (MSDS). By law (CHIP3) this should accompany any chemical that is purchased. However, if this is not available, or the chemical is old, then copies can be obtained from the manufacturer's website or information can sometimes be found in t
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7.1 Health problems associated with using chemicals

As described in Section 6.2, hazard is defined under COSHH as the inherently dangerous properties of a chemical or biological organism, and risk is defined as the likelihood of a chemical causing harm to people or to the environment.

There are several, more specific, known health problems associated with using chemicals.
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6.1 Control of Substances Hazardous to Health (COSHH) Regulations

For those companies involved in the handling of chemicals and/or biological material there are a number of additional regulations. These are known as the Control of Substances Hazardous to Health (COSHH) Regulations. These were introduced in 1988, and the last update was in 1999. These regulations apply to chemicals, biological hazards and dusts.

The essential requirements are that the employer must:

  • make an assessment of the health risk to empl
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5.2 Cryogenic liquids and ionising radiation safety

5.2.1 Cryogenic liquids

There are a number of hazards associated with cryogenic liquids, the main one being that when accidentally released the liquid expands hugely to form a gas (600 times in the case of nitrogen). The formation of such a large volume of gas can lead to asphyxiation in confined areas.

The other main hazard is cold burns (frostbite).

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5.1 Basic do's and don'ts and lone working

Some basic ‘do's and don'ts’ are:

  • Laboratory coats must be worn at all times.

  • When handling chemicals or sharps (any sharp object that can cause injury, particularly to the hands), observe good laboratory practice by wearing gloves. Latex or nitrile gloves are best, depending on the application.

  • There should be no eating, chewing gum, drinking, smoking or applying cosmetics in any laboratory.

  • No p
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4.2 Why do I need to know about first aid?

It takes only 3 to 4 minutes for a blocked airway to kill someone, but it can take more than 8 minutes for an ambulance to arrive on the scene. A simple procedure like opening an airway can save someone's life while you are waiting for professional help to arrive.

If you are working with harmful substances (chemicals, biological agents and dusts) you must know the first aid treatment if you are exposed. Do not expect a nurse or a doctor to know everything about every harmful substance.
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4.1 First aid

It is not required that students be trained in first aid. It is, however, important that a first aid kit is carried when you are likely to be away from immediate assistance. First aid must be rendered at once, and medical and relief help should be sought if necessary. It is important that appropriate first aid skills for use in the field are understood by those who might need them and that the procedures for enlisting help are known.

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3 Office safety

The relevant safety legislation for offices includes the Display Screen Equipment Regulations, which concern computer monitors and workstations. If electrical devices are used, then the Electricity at Work Regulations will apply. See Appendix A for a list of potential safety problems and considerations for offices and Appendix B for a checklist.

Click 'view document' to open Appendix A.

2 Legal requirements of health and safety in the UK

The Health and Safety at Work etc. Act (HSWA) 1974 states that:

  • It is the duty of every employer, so far as is reasonably practicable, to ensure the health, safety and welfare at work of all employees (this includes students).

  • It is the duty of every employee while at work to take reasonable care of himself (herself) and of other persons who may be affected by his (her) acts or omissions at work.

  • The employees must co
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1 History of health and safety

The discipline of health and safety is relatively modern, only developing in the last century. However, throughout the ages people have voiced their concerns about people being exposed to harmful substances. Hippocrates mentions in the 4th century BC that lead miners and workers tended to suffer from diseases. The phrase ‘mad as a hatter’ was coined because mercury used in the hat industry caused mental illness. In 1775 Pott reported that chimney s
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Learning outcomes

By the end of this unit you should be able to:

  • understand the legal framework of the Health and Safety at Work etc. Act 1974 and Regulations associated with it;

  • understand the employers’, employees’ and visitors’ duties;

  • evaluate hazards and risks in order to carry out a risk assessment;

  • understand the legal requirement to report any accident or dangerous occurrence;

  • develop risk assessments for scientific laborat
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Introduction

Ths unit is an adapted extract from the course Postgraduate research skills in science (STM895)

This unit is designed to introduce you to the concepts of health and safety within a science laboratory or in the field. There are a number of legal requirements that must be adhered to before carrying out work in a laboratory. One of these is the necessity to carry out risk assessments on the chemical and biological agents that are to be used as part of your practical work activities. As par
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References

Bauer, M. W. and Gaskell, G. (2002) Biotechnology: The Making of a Global Controversy, Cambridge University Press.
Bowring, F. (2003) Science, Seeds and Cyborgs, Verso, London.
Campbell, S. (2004) A genetically modified survey, Spiked 
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5 Summary

At the time of writing (2006) a relatively small number of types of GM crop have been grown globally, in a limited number of countries. The take-up of these crops has been relatively high in countries like the USA and Canada, but very much lower in Europe. However, there is a very rapid increase in the growth of GM crops in developing countries.

The technique most commonly used to introduce new genetic material into dicots has involved the use of a modified soil bacterium, Agrobacter
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4.3 Golden Rice in the public domain

In January 2000, the successful experiments were announced in a paper published in the American journal Science. This, in itself, is significant. Generally, work on genetic manipulation would be published in one of a number of more specialist journals. Publication in a journal like Science indicates that this was important work, likely to be of interest to a wider audience. In its ‘Notes for Authors’, the journal states that ‘Priority is given to papers that reveal novel c
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4.1 Vitamin A deficiency

Vitamin A, more properly known as retinol, is an important chemical intermediate in a number of biochemical processes in mammals. It is involved in vision, and is found in the rod cells of the retina of the eye. These cells are particularly important in seeing at low light levels, and night blindness is a symptom of vitamin A deficiency (VAD). Vitamin A is also involved in the proper functioning of the immune system. Children suffering from VAD are prone to serious infections, and often die f
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3.1 Insect resistance

We will now look briefly at the science underlying the traits introduced into commercial crops, which you explored in Activity 1; a useful place to start is by considering how the property of resistance to insects is acquired by crops.

Insect damage causes huge losses of agricultural crops each year. For example, without co
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2.1 Crown gall disease: genetic engineering in nature

A. tumefaciens causes crown gall disease in a wide range of dicotyledonous plants. (Dicotyledonous plants, are also known as dicots, have broad leaves with branching veins. An example would be a broad leaved tree like an oak. Narrow leaved plants with parallel grains such as grasses are known as monocotyledonous plant or monocots.) The infection normally occurs at the site of a wound in the plant. The disease gains its name from the large tumour-like swellings, or galls, that o
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1 Genetic manipulation of plants and GM crops: an introduction

In this unit we will consider the genetic manipulation of plants, and the production of GM crops. A great deal has been written about the science of GM crops and the controversial issues surrounding their introduction around the world. In the study time available, we will focus on a small number of selected issues.

In this unit you'll have the opportunity to learn more about the science that has been used to engineer a range of GM crops, and examine both the science and social concerns
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Acknowledgements

Grateful acknowledgement is made to the following sources for permission to reproduce material in this unit:

The content acknowledged below is Proprietary and used under licence (not subject to Creative Commons licence). See Terms and Conditions.

Figures

Figure 4 BP (2
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