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7.3 Selected to die: studies of the CNS

Recent evidence has revealed that during development in mice, cell death occurs in two phases. The first phase is at about E15–E17 days, during neuron proliferation, and will not be considered further here. The second phase at about P0–P5 in the mouse (where P0 is the day of birth) is during the period of innervation.

The evidence for the second phase is well established. Some 50 per cent of retinal ganglion cells die during this phase and here's what happens. Dennis O'Leary (1987)
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3.3 Variation

Fossil rodents are first found in rocks that date from around 65 million years ago (from the Eocene) and are thought to have evolved from insectivore/omnivore-type mammals that lived 100 million years ago (in the Cretaceous period). To say that they evolved from simply means that there probably is a direct line of descent but that the descendants have changed from their forebears. One of the most significant ways that evolutionary change can be brought about is by a process known as na
Author(s): The Open University

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4.3.1 Mapping what we know

Knowledge maps are often one of the first knowledge management representations to emerge, in an effort to add value over the simple corporate intranet search which returns lists of ‘hits’ that are undifferentiated beyond a ranking in terms of keyword matches. Knowledge maps, like other forms of cartography, should communicate a ‘big picture’ by overlaying meaningful structure on to raw resources.


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SFjRO - Cancérologie Digestive - Dijon 2015: Chirurgie rectale:TME & TEM (Vidéo)

Titre: SFjRO - Cancérologie Digestive - Dijon 2015: Chirurgie rectale:TME & TEM

Conférence filmée dans le cadre des Cours nationaux de radiothérapie de la Société Française des jeunes Radiothérapeutes Oncologues qui ont eu lieu les 19 & 20 juin 2015 à la faculté de Médecine de Dijon.

Intervenant (e)(s) : Pr. Pierre-Emmanuel Colombo ...
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Enterprise in the sports industry
This presentation discusses Drucker's thesis that failure is a "good thing" if the opportunities that arise from such failure allow the development of personal and enterprise skills
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http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Caissons

The following resources are part of the module Civil Engineering Technology from the 2009/10 BSc (Hons) degree programme Commercial Management and Quantity Surveying. It covers the four main types of caissons; box caissons, open caissons, compressed air caisson, and monoliths as well as related structures and construction methods.

For an alternative vers
Author(s): EngCETL

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(ii) National emergency, crisis or new development

Legislation may be passed because of some national emergency or crisis which emerges during the Government's period in office. For example, the Anti-Terrorism, Crime and Security Act 2001 was introduced to respond to the new situation arising from the terrorist attacks on New York and Washington on 11 September 2001. The aim of the 2001 Act was to cut off terrorist funding, ensure that Government departments and agencies have the power to collect and share information required for countering
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3.2 Room to rattle: modelling thermal expansion

In general, as the temperature of a piece of solid is raised the volume it occupies increases. I say ‘in general’ because as we shall see it is not always the case, and we ought to investigate whether we can exert any control over the phenomenon – which could be useful. Evidently, if a solid expands, the average spacing between its constituent parts must have increased. Since matter is made up of atoms, the issue is really about the volume occupied by the arrangements of atoms that make
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Acknowledgements

The content acknowledged below is Proprietary (see terms and conditions) and is used under licence.

Unit Image

Samantha S.:www.flickr.com/photos/punkyo/371379544/

All materials included in this unit are derived from content originated at the Open University.

Don't miss out:

1. Join over 200,000 students, currently studying with The Open University [Author(s): The Open University

1.4 How precise are the measurements?

Scientists are always trying to get better and more reliable data. One way of getting a more precise measurement might be to switch to an instrument with a more finely divided scale. Figure 4 shows parts of two thermometers placed side by side to record the air temperature in a room.

Figure 4
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Tesla and the Art of Fugue
UCL Lunch Hour Lectures are open and free to the public and take place on Tuesdays and Thursdays in the Darwin Lecture Theatre, UCL, Gower Street, London WC1E 6BT. They will resume in Autumn 2008. In the meantime, a number are available below.
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1 Dividing the planet

A good globe can set you back quite a lot of money. Of course, I don't mean the little moulded plastic planets or the globes you can blow up as if the world were a beach ball, but the decent sized ones that sit solidly on turned wooden bases and quietly emanate authority from the corner of a room. Yet these days, it hardly seems worthwhile making such an investment. Countries appear to change their colour, their shape or their name with remarkable rapidity.

It has become a cliché to po
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Papier-maché : Stappenplan
1.jpg

Dit document legt in elf stappen uit hoe je het best aan de slag gaat met papier-maché.

 


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4 Environmental factors and organisations: review

The primary thrust of this unit has been to emphasise the need for all organisations to acknowledge the influence of their environments and, in turn, the impact of organisations on their context. We have argued that the commercial environment is characterised primarily by the growing trend toward globalisation. To a much greater extent than ever before we live in a global village where goods and services will be produced wherever they can be provided at the least cost. Consumers in the West i
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2.3 Scaling up

They may look at dozens of alleles, and involve thousands of people, but existing screening programmes have been concerned with individual genes. But the technologies now being developed will soon permit the recording of hundreds of genes at a time. So-called gene chips combine the skills of microchip designers with DNA sequence information to offer rapid, easy-to-read results for an individual covering hundreds of genetic variants. A gene chip is a thin slice of glass about the
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1.10 Other considerations

While visitors to Aberdulais Falls seem genuinely to enjoy the experience, there is a possibility that only when they arrive at the site do they realise it is primarily an industrial site, with an attractive waterfall. There is no mention in the Aberdulais Falls title of it being an industrial site. Even the National Trust Handbook and website are a little ambiguous, using the phrase ‘Famous waterfalls and fascinating industrial site’ in its literature. Clearly not all visitors are member
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1.5.7 Referencing

We mentioned above that we need to reference sources to ensure we abide by copyright legislation. But there is another reason we need to give accurate references to items we use – so we can share it.

Consider this scenario. A friend says they’ve just read an interesting article where Joshua Schachter, founder of Delicious has spoken about why it isn’t a faceted search system, and you should read it. How would you go about finding it? Would you start looking in a news database, a s
Author(s): The Open University

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Shape Grammars for Innovative Hybrid Typological Design
This paper describes a new methodology of deriving innovative hybrid designs using shape grammars of heterogeneous designs. The method is detailed within three phases of shape grammars: analysis, synthesis and evaluation. In the analysis phase, the research suggests that original rules of each design component are grouped in subclass rule sets to facilitate rule choices. Additionally, adding new hybrid rules to original rules expands the options available to the grammar user. In the synthesis ph
Author(s): Al-kazzaz, Dhuha; Bridges, Alan; Chase, Scott

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5 Conclusion

The argument underpinning this unit has stressed the dangers of seeing implementation as somehow separate from the policy process, or as just one stage within it. Instead it has been emphasised that it is vital to place implementation centrally within that process – involving negotiation, learning and adaptation. Others too have come to regard this as central to the policy process. In the first edition of their book on implementation, Pressman and Wildavsky emphasise the disjunction between
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Learning outcomes

After studying this unit you should:

  • be able to explain what is meant by the term ‘the global dimension’;

  • be familiar with the terminology used in relation to the global dimension;

  • know why the inclusion of the global dimension in the primary school curriculum is important;

  • know how the global dimension can enhance the primary school curriculum;

  • be able to plan the global dimension into the secondary curriculum.


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