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7.340 Regenerative Medicine: from Bench to Bedside (MIT)
Regenerative medicine involves the repair and regeneration of tissues for therapeutic purposes, such as replacing bone marrow in leukemia, cartilage in osteoarthritis or cells of the heart after a heart attack. In this course, we will explore basic mechanisms of how cells differentiate into specific tissues in response to a variety of biologic signaling molecules. We will discuss the use of such factors for in vitro tissue production. We will also study the cellular mechanisms involved in the cl
Author(s): Petra Simic

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Environmental Risk Assessment - Approaches, Experiences and Information Sources
This website provides access to a report from the European Environment Agency that gives a broad overview of approaches and experiences on how to assess ecological and human information on health risks. The chapters are targeted to different users such as industry, scientists and policy makers. Links to information sources, organizations, software models, EU legislation, and publications are also provided.
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Social issues and GM crops
The genetic manipulation of plants and animals and their use in agriculture is one of the most controversial scientific developments of recent times. This unt takes a look at the 'science behind the headlines' and the complex interactions between scientific and social factors. By the end of the unit it's hoped that you will have a clearer idea of both what is GM makes possible as well as what may be thought desirable.
Author(s): The Open University

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5.3.1 Allosteric regulation
In this unit we explore how proteins are the 'doers' of the cell. They are huge in number and variety and diverse in structure and function, serving both the structural building blocks and the functional machinery of the cell. Just about every process in every cell requires specific proteins. The basic principles of protein structure and function which are reviewed in this unit are crucial to understanding how proteins perform their various roles.
Author(s): The Open University

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Stem Cells: Programming and Personalized Medicine
After years of relentless lab work, rising and falling expectations, and the challenge of a sometimes hostile public, Rudolf Jaenisch says, “The scenario that looked like a fantasy … has come closer to reality. We can study complex human diseases in a Petri dish and potentially contribute to therapy.” In this l
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5.2 All proteins bind other molecules
In this unit we explore how proteins are the 'doers' of the cell. They are huge in number and variety and diverse in structure and function, serving both the structural building blocks and the functional machinery of the cell. Just about every process in every cell requires specific proteins. The basic principles of protein structure and function which are reviewed in this unit are crucial to understanding how proteins perform their various roles.
Author(s): The Open University

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ME++ The Cyborg Self and the Networked City
Throughout history, humans have created unique physical spaces in which to live, work and socialize. But the digital age has completely transformed the places in which we conduct our affairs, according to William J. Mitchell. We don’t congregate at the town bank any more for financial transactions. We visit ATMs or bank online.
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Proteins
In this unit we explore how proteins are the 'doers' of the cell. They are huge in number and variety and diverse in structure and function, serving both the structural building blocks and the functional machinery of the cell. Just about every process in every cell requires specific proteins. The basic principles of protein structure and function which are reviewed in this unit are crucial to understanding how proteins perform their various roles.
Author(s): The Open University

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Transportation, the Built Environment and Greenhouse Gas Emissions in Developing Cities
It seems that income and travel are inextricably linked. As communities gain wealth and prosperity, their travel footprint increases. While this relationship affords benefits to those in developed nations, it is not scalable. Global population is projected to increase by nearly 2 billion people by 2030. If this newly adde
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Keynote Presentation: Academic Perspectives
Very simply stated, systems biology attempts to “capture the dynamic nature of living systems.” To accomplish this, says Hood, you “have to bring together the flavors of biology, chemistry, computer science, engineering and physics,” among others. It’s a vast area to tackle. But with tools like the internet and digital
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Bioengineering at MIT: Building Bridges Between the Sciences, Engineering and Health Care (Part Two
Glycomics, the study of sugars’ role in living systems, is a relative newcomer to the revolution in molecular biology. In fact, Ram Sasisekharan remembers how colleagues told him “not to work on carbohydrates -- that it was useless.” But his research has shown that glycans, observed as long chains or intricat
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Nanotechnology and the Study of Human Diseases
Subra Suresh fleshes out the promise of nanotechnology, at least in regard to our understanding of disease. His talk, which focuses on malaria and its impact on red blood cells, demonstrates how the fields of engineering, biology and medicine are converging.

To function properly, he explains, a red blood cel

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Metastasis
No diagnosis of cancer is welcome, but some scenarios are more dreaded than others. Richard Hynes discusses what happens “when cells in the primary tumor lose their sense of address and wander off to places they’re not supposed to go.” His talk lays out the process of invasion, by which the cancer spreads into
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The Next Frontier: Bioelectronic Interfaces
In the beginning, there was ENIAC. The first electrical computer could do 5,000 additions or subtractions per second, recounts Mark Reed, as long as people with shopping carts full of vacuum tubes jumped to the rescue each time the behemoth suffered a burnout. Then came transistors, and integrated circuits, greatly incre
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8.2 Working with bio-hazardous material (human material, microbiological agents, plant pathogens)
Health, safety and risk assessment are of paramount importance both in the laboratory and the field. This unit will help make you more aware of the hazards and risks involved in laboratory and field-based research work, as well as giving you an overview of the legal requirements attached to this work. The unit discusses issues involved in the handling chemical and biological agents, basic safety procedures and common field-work hazards.
Author(s): The Open University

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Imperative of Science and Technology in Accelerating African and Rwandan Development
The news these days from Africa isn’t all bad. In fact, in some places, it’s downright hopeful, as Rwandan President Paul Kagame attests. “Our continent is no longer all about violence and disease and human disasters that scarred many African countries in recent decades,” says Kagame. “We are now becoming a continen
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Leading Change: A Conversation with Ron Williams
In what Dean Dave Schmittlein bills as a master class, Ronald A. Williams discusses how an emphasis on new technology and application of basic values helped turn around the health care giant Aetna.

Williams’ case study begins in 2001, when he arrived to find a corporation bleeding out -- having lost $280 million in th

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China's Development and China-U.S. Relations
MIT President Susan Hockfield hails a new era of collaboration between the Institute and China, and Zhou Wenzhong, Ambassador Extraordinary and Plenipotentiary of the People's Republic of China, discusses the larger relationship between his country and the U.S., particularly in light of the economic crisis
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End of of unit questions
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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Summary of Section 8
This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nu
Author(s): The Open University

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