Keynote Presentation: Academic Perspectives
Very simply stated, systems biology attempts to “capture the dynamic nature of living systems.” To accomplish this, says Hood, you “have to bring together the flavors of biology, chemistry, computer science, engineering and physics,” among others. It’s a vast area to tackle. But with tools like the internet and digital
Bioengineering at MIT: Building Bridges Between the Sciences, Engineering and Health Care (Part Two
Glycomics, the study of sugars’ role in living systems, is a relative newcomer to the revolution in molecular biology. In fact, Ram Sasisekharan remembers how colleagues told him “not to work on carbohydrates -- that it was useless.” But his research has shown that glycans, observed as long chains or intricat
Nanotechnology and the Study of Human Diseases
Subra Suresh fleshes out the promise of nanotechnology, at least in regard to our understanding of disease. His talk, which focuses on malaria and its impact on red blood cells, demonstrates how the fields of engineering, biology and medicine are converging.
To function properly, he explains, a red blood cel
Metastasis
No diagnosis of cancer is welcome, but some scenarios are more dreaded than others. Richard Hynes discusses what happens “when cells in the primary tumor lose their sense of address and wander off to places they’re not supposed to go.” His talk lays out the process of invasion, by which the cancer spreads into
Electronics on Plastic: A Solution to the Energy Challenge, or a Pipe Dream?
As urgency to address climate change mounts, there’s ever greater interest in harnessing the unlimited potential of the sun to replace fossil fuels. This tantalizing prospect has inspired a raft of new scientific ventures, reports Stephen Forrest.
A theoretical field of silicon solar cells that is 1
Lunch with a Laureate: Robert Horvitz
As an undergraduate at MIT, Robert Horvitz did not take a biology course until his senior year. But after only six weeks into his first class with professor Cy Leventhal, he realized this was the field for him. He boldly asked for a recommendation as part of his application to grad school—in biology. “Is it too late?” he
Lunch with a Laureate: Jack Szostak
Jack Szostak started his first lab as a “freshly minted assistant professor” working in DNA recombination and repair reactions. While researchers had known for years that the broken ends of DNA strands behaved differently from broken DNA in the middle of the strand, they did not know the details. Because cells do not like b
How organisations work together to build a sustainable supply chain: The case of Nespresso
Executive Doctorate (DBA) alumna Gabriela Alvarez discusses the impact of the programme and her research with Toby Thompson. LinkedIn Profile: http://linkd.in/dHMAns
DBA supervisor perspective: The role of personal values as antecedent to management behaviour...
DBA supervisor perspective: The role of personal values as antecedent to management behaviour and performance in a tenanted pub retail business in a UK regional Brewer.
Prof Kim Turnbull James talks about the doctoral research of Dr Andrew Wood and impact that the Executive Doctorate (DBA) programme had on him.
Luminescent Solar Concentrators Explained
Researchers are well along in designing a highly efficient, inexpensive solar cell, but the big barrier to the dissemination of solar power in society remains the problem of installation, says Marc Baldo.
As an engineer, Baldo expresses confidence that “we’re going to mow down” the problem of producing a g
Fellowship Hall at Guild Memorial
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5.4 The medical chemistry strategy
The search for new medicinal products is one of the major driving forces behind the development and application of new synthetic methods. This unit focuses on a specific case study, which follows the development of a drug for the treatment of high blood pressure. It is a particularly good example of the application of organic chemistry in the pharmaceutical industry, and illustrates the scientific processes that are involved in the development of any new drug.
5.3 Project initiation
The search for new medicinal products is one of the major driving forces behind the development and application of new synthetic methods. This unit focuses on a specific case study, which follows the development of a drug for the treatment of high blood pressure. It is a particularly good example of the application of organic chemistry in the pharmaceutical industry, and illustrates the scientific processes that are involved in the development of any new drug.
5.2 The pharmaceutical background
The search for new medicinal products is one of the major driving forces behind the development and application of new synthetic methods. This unit focuses on a specific case study, which follows the development of a drug for the treatment of high blood pressure. It is a particularly good example of the application of organic chemistry in the pharmaceutical industry, and illustrates the scientific processes that are involved in the development of any new drug.
5.1 The medical background
The search for new medicinal products is one of the major driving forces behind the development and application of new synthetic methods. This unit focuses on a specific case study, which follows the development of a drug for the treatment of high blood pressure. It is a particularly good example of the application of organic chemistry in the pharmaceutical industry, and illustrates the scientific processes that are involved in the development of any new drug.
2 Video activity
The search for new medicinal products is one of the major driving forces behind the development and application of new synthetic methods. This unit focuses on a specific case study, which follows the development of a drug for the treatment of high blood pressure. It is a particularly good example of the application of organic chemistry in the pharmaceutical industry, and illustrates the scientific processes that are involved in the development of any new drug.
1 The chemical industry
The search for new medicinal products is one of the major driving forces behind the development and application of new synthetic methods. This unit focuses on a specific case study, which follows the development of a drug for the treatment of high blood pressure. It is a particularly good example of the application of organic chemistry in the pharmaceutical industry, and illustrates the scientific processes that are involved in the development of any new drug.
3 Chromosome structure and DNA replication
Genomes are composed of DNA, and a knowledge of the structure of DNA is essential to understand how it can function as hereditary material. DNA is remarkable, breathtakingly simple in its structure yet capable of directing all the living processes in a cell, the production of new cells and the development of a fertilized egg to an individual adult. DNA has three key properties: it is relatively stable; its structure suggests an obvious way in which the molecule can be duplicated, or replicated;
1 1.2 How DNA is replicated
Genomes are composed of DNA, and a knowledge of the structure of DNA is essential to understand how it can function as hereditary material. DNA is remarkable, breathtakingly simple in its structure yet capable of directing all the living processes in a cell, the production of new cells and the development of a fertilized egg to an individual adult. DNA has three key properties: it is relatively stable; its structure suggests an obvious way in which the molecule can be duplicated, or replicated;
1.1.1 The chemical structure of DNA
Genomes are composed of DNA, and a knowledge of the structure of DNA is essential to understand how it can function as hereditary material. DNA is remarkable, breathtakingly simple in its structure yet capable of directing all the living processes in a cell, the production of new cells and the development of a fertilized egg to an individual adult. DNA has three key properties: it is relatively stable; its structure suggests an obvious way in which the molecule can be duplicated, or replicated;
