Contact

• workApplied Health Research Building
  University Park
  Nottingham
  NG7 2RD
  UK
• work0115 7486679
• Ruth.Jack@nottingham.ac.uk

Biography

Dr Ruth Jack studied Applied Statistics at the University of Reading, before obtaining an MSc in Environmental Epidemiology and Policy at the London School of Hygiene and Tropical Medicine. She worked in the Department of Public Health Sciences and the Thames Cancer Registry, both within King's College London. While working at KCL as an epidemiologist, she completed her PhD on cancer incidence, stage, treatment and survival in different ethnic groups in South East England. She joined Public Health England working in the London and Nottingham offices as part of the National Cancer Registration and Analysis Service, before joining the University of Nottingham in 2018.

Expertise Summary

Keywords:

Epidemiology; database analysis; electronic health records; ethnicity; inequalities; mental health

Research Summary

ORCID iD: 0000-0003-4009-020X

Ruth is funded by the NIHR Nottingham Biomedical Research Centre Mental Health & Technology theme. Using large, anonymised databases of electronic health records from primary and secondary care, the team are developing and validating novel methods for identifying and quantifying unexpected or adverse reactions to drugs used to treat mental health disorders, as well as identifying trends and variation in prescribing in different population groups. We are also examining clustering of medicines within patient groups prescribed medicines for their mental health to identify patterns of co-prescribing and contraindicated combinations of treatments.

Recent Publications

• VINOGRADOVA, YANA, JACK, RUTH H, PRASAD, VIBHORE, COUPLAND, CAROL, MORRISS, RICHARD and HOLLIS, CHRIS, 2024. A protocol to assess antipsychotics prescribing and physical health monitoring in children and young people: a cohort study using primary care data from QResearch: medRxiv medRxiv. 2024.07. 18.24310326
• AYLING, K., BROWN, M., CARLISLE, S., BENNETT, R., BUCHANAN, H., DUMBLETON, J., HAWKEY, C., HOSCHLER, K., JACK, R. H., NGUYEN-VAN-TAM, J., ROYAL, S., TURNER, D., ZAMBON, M., FAIRCLOUGH, L. and VEDHARA, K., 2024. Optimizing mood prior to influenza vaccination in older adults: A three-arm randomized controlled trial: Health Psychol Health Psychology. 43(2), 77-88
• JACK, RUTH H, JOSEPH, REBECCA M, COUPLAND, CAROL A C, HALL, CHARLOTTE L and HOLLIS, CHRIS, 2023. Impact of the COVID-19 pandemic on incidence of tics in children and young people: a population-based cohort study. EClinicalMedicine. 57, 101857
• FRY, ANNA, WHITE, BECKY, NAGARWALLA, DIANA, SHELTON, JON and JACK, RUTH H, 2023. Relationship between ethnicity and stage at diagnosis in England: a national analysis of six cancer sites. BMJ open. 13(1), e062079

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• VINOGRADOVA, YANA, JACK, RUTH H, PRASAD, VIBHORE, COUPLAND, CAROL, MORRISS, RICHARD and HOLLIS, CHRIS, 2024. A protocol to assess antipsychotics prescribing and physical health monitoring in children and young people: a cohort study using primary care data from QResearch: medRxiv medRxiv. 2024.07. 18.24310326
• AYLING, K., BROWN, M., CARLISLE, S., BENNETT, R., BUCHANAN, H., DUMBLETON, J., HAWKEY, C., HOSCHLER, K., JACK, R. H., NGUYEN-VAN-TAM, J., ROYAL, S., TURNER, D., ZAMBON, M., FAIRCLOUGH, L. and VEDHARA, K., 2024. Optimizing mood prior to influenza vaccination in older adults: A three-arm randomized controlled trial: Health Psychol Health Psychology. 43(2), 77-88
• JACK, RUTH H, JOSEPH, REBECCA M, COUPLAND, CAROL A C, HALL, CHARLOTTE L and HOLLIS, CHRIS, 2023. Impact of the COVID-19 pandemic on incidence of tics in children and young people: a population-based cohort study. EClinicalMedicine. 57, 101857
• FRY, ANNA, WHITE, BECKY, NAGARWALLA, DIANA, SHELTON, JON and JACK, RUTH H, 2023. Relationship between ethnicity and stage at diagnosis in England: a national analysis of six cancer sites. BMJ open. 13(1), e062079
• JACK, R. H., COUPLAND, C. A. C., JOSEPH, R. M., HOLLIS, C., MORRISS, R., KNAGGS, R. D., CIPRIANI, A., CORTESE, S. and HIPPISLEY-COX, J., 2023. Importance of accurate and accessible recording of healthcare contacts in mental health: BMC Med BMC Med. 21(1), 346
• JACK, R. H., JOSEPH, R. M., HOLLIS, C., HIPPISLEY-COX, J., BUTLER, D., WALDRAM, D. and COUPLAND, C., 2023. Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data: BMJ Ment Health 26(1),
• JOSEPH, R. M., KNAGGS, R. D., COUPLAND, C. A. C., TAYLOR, A., VINOGRADOVA, Y., BUTLER, D., GERRARD, L., WALDRAM, D., IYEN, B., AKYEA, R. K., ASHCROFT, D. M., AVERY, A. J. and JACK, R. H., 2023. Frequency and impact of medication reviews for people aged 65 years or above in UK primary care: an observational study using electronic health records: BMC Geriatr BMC Geriatrics. 23(1), 435
• JOSEPH, R.M., JACK, R.H., MORRISS, R., KNAGGS, R.D., BUTLER, D., HOLLIS, C., HIPPISLEY-COX, J. and COUPLAND, C., 2022. The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records BMC Medicine. 20(1), 43
• JOSEPH, REBECCA M., JACK, RUTH H., MORRISS, RICHARD, KNAGGS, ROGER DAVID, BUTLER, DEBBIE, HOLLIS, CHRIS, HIPPISLEY-COX, JULIA and COUPLAND, CAROL, 2022. Association between mirtazapine use and serious self-harm in people with depression: an active comparator cohort study using UK electronic health records EVIDENCE-BASED MENTAL HEALTH. 25(4), 169-176
• JOSEPH RM, JACK RH, MORRISS R, KNAGGS RD, HOLLIS C, HIPPISLEY-COX J and COUPLAND C, 2021. PROTOCOL: A cohort study examining the association between mirtazapine and mortality risk in adults with a diagnosis of depression medRxiv. Preprint Server, 2021.02.08.21250305
• JACK RH, JOSEPH RM, COUPLAND C, BUTLER D, HOLLIS C, MORRISS RM, KNAGGS RD, CIPRIANI A, CORTESE S and HIPPISLEY-COX J, 2020. Secondary care specialist visits made by children and young people prescribed antidepressants in primary care: a descriptive study using the QResearch database. BMC Medicine. 18, 93
• WELCH, C.A., SWEETING, M.J., LAMBERT, P.C., RUTHERFORD, M.J., JACK, R.H., WEST, D., ADLAM, D. and PEAKE, M.D., 2020. Impact on survival of modelling increased surgical resection rates in patients with non-small-cell lung cancer and cardiovascular comorbidities: a VICORI study British Journal of Cancer. Published Online First: 11 May 2020,
• JACK RH, HOLLIS C, COUPLAND C, MORRISS R, KNAGGS RD, BUTLER D, CIPRIANI A, CORTESE S and HIPPISLEY-COX J, 2020. Incidence and prevalence of primary care antidepressant prescribing in children and young people in England, 1998–2017: A population-based cohort study PLOS Medicine. 17(7), e1003215
• JACK RH, HOLLIS C, COUPLAND C, MORRISS R, KNAGGS RD, CIPRIANI A, CORTESE, S. and HIPPISLEY-COX, J., 2019. Trends in antidepressant prescriptions in children and young people in England, 1998-2017: protocol of a cohort study using linked primary care and secondary care datasets. Evidence Based Mental Health. Published Online First: 28 June 2019,
• KENNEDY, M.P.T., CHEYNE, L., DARBY, M., PLANT, P., MILTON, R., ROBSON, J.M., GILL, A., MALHOTRA, P., ASHFORD-TURNER, V., RODGER, K., PARAMASIVAM, E., JOHNSTONE, A., BHARTIA, B., KARTHIK, S., FOSTER, C., LOVATT, V., HEWITT, F., CRESSWELL, L., COUPLAND, V.H., LÜCHTENBORG, M., JACK, R.H., MOLLER, H. and CALLISTER, M.E.J., 2018. Lung cancer stage-shift following a symptom awareness campaign Thorax. 73(12), 1128-1136
• TATARU, D., SPENCER, K., BATES, A., WIECZOREK, A., JACK, R.H., PEAKE, M.D., LIND, M.J. and LÜCHTENBORGA, M., 2018. Variation in geographical treatment intensity affects survival of non-small cell lung cancer patients in England. Cancer Epidemiology. 57, 13-23
• KHAKWANI, A., JACK, R.H., VERNON, S., DICKINSON, R., WOOD, N., HARDEN, S., BECKETT, P., WOOLHOUSE, I. and HUBBARD, R.B., 2017. Apples and pears? A comparison of two sources of national lung cancer audit data in England. ERJ Open Research. 3(3),
• MOLLER, H., HENSON, K., LUCHTENBORG, M., BROGGIO, J., CHARMAN, J., COUPLAND, V.H., DAVIES, E., JACK, R. H., SULLIVAN, R., VEDSTED, P., HORGAN, K., PEARCE, N. and PURUSHOTHAM, A., 2016. Short-term breast cancer survival in relation to ethnicity, stage, grade and receptor status: national cohort study in England. British Journal of Cancer. 115(11), 1408-1415
• KANANI, R., DAVIES, E.A., HANCHETT, N. and JACK, R.H., 2016. The association of mood disorders with breast cancer survival: an investigation of linked cancer registration and hospital admission data for South East England. Psycho-Oncology. 25(1), 19-27
• JACK, R.H., ROBSON, T. and DAVIES, E.A., 2016. The varying influence of socioeconomic deprivation on breast cancer screening uptake in London. Journal of Public Health. 38(2), 330-4
• DAVIES, E.A., COUPLAND, V.H., DIXON, S., MOKBEL, K. and JACK, R.H., 2016. Comparing the case mix and survival of women receiving breast cancer care from one private provider with other London women with breast cancer: pilot data exchange and analyses. BMC Cancer. 16, 421
• COUPLAND, V.H., KONFORTION, J., JACK, R.H., ALLUM, W., KOCHER, H.M., RIAZ, S. P., LÜCHTENBORG, M. and MØLLER, H., 2016. Resection rate, hospital procedure volume and survival in pancreatic cancer patients in England: Population-based study, 2005–2009. European Journal of Surgical Oncology (EJSO). 42(2), 190-196
• TATARU, D., JACK, R.H., LIND, M.J., MOLLER, H. and LUCHTENBORG, M., 2015. The effect of emergency presentation on surgery and survival in lung cancer patients in England, 2006-2008. Cancer Epidemiology. 39(4), 612-6
• JONES, C.E.L., MABEN, J., LUCAS, G., DAVIES, E.A., JACK, R.H. and REAM, E., 2015. Barriers to early diagnosis of symptomatic breast cancer: a qualitative study of Black African, Black Caribbean and White British women living in the UK. BMJ Open. 5(3),
• RATNESWAREN, T., JACK, R.M., TATARU, D. and DAVIES, E.A., 2014. The survival of patients with high grade glioma from different ethnic groups in South East England. Journal of Neuro-Oncology. 120(3), 531-536
• PAL, S., LÜCHTENBORG, M., DAVIES, E.A. and JACK, R.H., 2014. The treatment and survival of patients with triple negative breast cancer in a London population. SpringerPlus. 3(1), 553
• KONFORTION, J., JACK, R.H. and DAVIES, E.A., 2014. Coverage of common cancer types in UK national newspapers: a content analysis. BMJ Open. 4(7),
• KONFORTION, J., COUPLAND, V.H., KOCHER, H.M., ALLUM, W., GROCOCK, M.J. and JACK, R.J., 2014. Time and deprivation trends in incidence of primary liver cancer subtypes in England. Journal of Evaluation in Clinical Practice. 20(4), 498-504
• JONES, C.EL., MABEN, J., JACK, R.H., DAVIES, E.A., FORBES, L.J.L., LUCAS, G. and REAM, E., 2014. A systematic review of barriers to early presentation and diagnosis with breast cancer among black women. BMJ Open. 4(2),
• JACK, R.H., MØLLER, H., ROBSON, T. and DAVIES, E.A., 2014. Breast cancer screening uptake among women from different ethnic groups in London: a population-based cohort study. BMJ Open. 4(10),
• JACK, R.H., KONFORTION, J., COUPLAND, V.H., KOCHER, H.M., BERRY, D.P., ALLUM, W., LINKLATER, K.M. and MOLLER, H., 2013. Primary liver cancer incidence and survival in ethnic groups in England, 2001-2007 Cancer Epidemiology. 37(1), 34-8
• JACK, R.H., DAVIES, E.A., RENSHAW, C., TUTT, A., GROCOCK, M.J., COUPLAND, V.H. and MOLLER, H., 2013. Differences in breast cancer hormone receptor status in ethnic groups: a London population. European Journal of Cancer. 49(3), 696-702
• COUPLAND, V. H., LAGERGREN, J., LUCHTENBORG, M., JACK, R. H., ALLUM, W., HOLMBERG, L., HANNA, G. B., PEARCE, N. and MOLLER, H., 2013. Hospital volume, proportion resected and mortality from oesophageal and gastric cancer: a population-based study in England, 2004-2008. Gut. 62(7), 961-6
• RIAZ, S.P., LÜCHTENBORG, M., JACK, R.H., COUPLAND, V.H., LINKLATER, K.M., PEAKE, M.D. and MØLLER, H., 2012. Variation in surgical resection for lung cancer in relation to survival: Population-based study in England 2004–2006. European Journal of Cancer. 48(1), 54-60
• JACK, R.H., DAVIES, E.A. and MØLLER, H., 2012. Breast cancer and age in Black and White women in South East England. International Journal of Cancer. 130(5), 1227-1229
• DONALDSON, C.D., JACK, R.H., MOLLER, H. and LUCHTENBORG, M., 2012. Oral cavity, pharyngeal and salivary gland cancer: disparities in ethnicity-specific incidence among the London population. Oral Oncology. 48(9), 799-802
• COUPLAND, V. H., LAGERGREN, J., KONFORTION, J., ALLUM, W., MENDALL, M. A., HARDWICK, R. H., LINKLATER, K. M., MØLLER, H. and JACK, R. H., 2012. Ethnicity in relation to incidence of oesophageal and gastric cancer in England. British Journal of Cancer. 107(11), 1908-1914
• JACK, R. H., DAVIES, E. A. and MØLLER, H., 2011. Lung cancer incidence and survival in different ethnic groups in South East England. British Journal of Cancer. 105(7), 1049-1053
• COUPLAND, V.H., MADDEN, P., JACK, R. H., MOLLER, H. and DAVIES, E.A., 2011. Does place of death from cancer vary between ethnic groups in South East England? Palliative Medicine. 25(4), 314-22
• RENSHAW, C., JACK, R.H., DIXON, S., MØLLER, H. and DAVIES, E.A., 2010. Estimating attendance for breast cancer screening in ethnic groups in London. BMC Public Health. 10(1), 157
• JACK, R.H. and HOLMBERG, L., 2010. Waiting times for radiotherapy after breast cancer. British Medical Journal. 340, c1007
• JACK, R.H., DAVIES, E.A. and MOLLER, H., 2010. Prostate cancer incidence, stage at diagnosis, treatment and survival in ethnic groups in South-East England. BJU International. 105(9), 1226-30
• WONG, Y.N., JACK, R.H., MAK, V., HENRIK, M. and DAVIES, E.A., 2009. The epidemiology and survival of extrapulmonary small cell carcinoma in South East England, 1970-2004. BMC Cancer. 9, 209
• JACK, R.H., DAVIES, E.A. and MØLLER, H., 2009. Breast cancer incidence, stage, treatment and survival in ethnic groups in South East England. British Journal of Cancer. 100(3), 545-550
• CURRIN, L.G., JACK, R.H., LINKLATER, K.M., MAK, V., MOLLER, H. and DAVIES, E.A., 2009. Inequalities in the incidence of cervical cancer in South East England 2001-2005: an investigation of population risk factors. BMC Public Health. 9, 62
• PHEKOO, K.J., JACK, R.H., DAVIES, E., MØLLER, H. and SCHEY, S.A., 2008. The incidence and survival of Waldenström's Macroglobulinaemia in South East England. Leukemia Research. 32(1), 55-59
• BENNETT, V.A., DAVIES, E.A., JACK, R.H., MAK, V. and MOLLER, H., 2008. Histological subtype of lung cancer in relation to socio-economic deprivation in South East England. BMC Cancer. 8, 139
• PATEL, N., ADATIA, R., MELLEMGAARD, A., JACK, R. and MØLLER, H., 2007. Variation in the use of chemotherapy in lung cancer British Journal of Cancer. 96(6), 886-890
• JACK, R.H., DAVIES, E.A., ROBINSON, D., SAINSBURY, R. and MOLLER, H., 2007. Radiotherapy waiting times for women with breast cancer: a population-based cohort study. BMC Cancer. 7, 71
• JACK, R.H., DAVIES, E.A. and MØLLER, H., 2007. Testis and prostate cancer incidence in ethnic groups in South East England. International Journal of Andrology. 30(4), 215-221
• PATEL, N., ING, L., JACK, R. and MØLLER, H., 2006. Factors Influencing the Use of Antitumoral Chemotherapy in the South East of England. Journal of Chemotherapy. 18(3), 318-324
• JACK, R.H., LINKLATER, K.M., HOFMAN, D., FITZPATRICK, J. and MOLLER, H., 2006. Ethnicity coding in a regional cancer registry and in Hospital Episode Statistics. BMC Public Health. 6, 281
• JACK, R.H., GULLIFORD, M.C., FERGUSON, J. and MOLLER, H., 2006. Explaining inequalities in access to treatment in lung cancer. Journal of Evaluation in Clinical Practice. 12(5), 573-82
• DAVIES, E., LINKLATER, K. M., JACK, R. H., CLARK, L. and MØLLER, H., 2006. How is place of death from cancer changing and what affects it? Analysis of cancer registration and service data. British Journal of Cancer. 95(5), 593-600
• ROBINSON, D., MASSEY, T., DAVIES, E., JACK, R.H., SEHGAL, A. and MØLLER, H., 2005. Waiting times for radiotherapy: variation over time and between cancer networks in southeast England. British Journal of Cancer. 92(7), 1201-1208
• GULLIFORD, M.C., JACK, R.H., ADAMS, G. and UKOUMUNNE, O.C., 2004. Availability and structure of primary medical care services and population health and health care indicators in England. BMC Health Services Research. 4(1), 12
• JACK, R.H., GULLIFORD, M.C., FERGUSON, J. and MØLLER, H., 2003. Geographical inequalities in lung cancer management and survival in South East England: evidence of variation in access to oncology services? British Journal of Cancer. 88(7), 1025-1031