Postgraduate Research Student,
The aim of the project is to develop 3D conductive hydrogels and determine the immune output when an electrical stimuli is applied through a variety of assays, as an in vitro model for wound healing.… read more
The aim of the project is to develop 3D conductive hydrogels and determine the immune output when an electrical stimuli is applied through a variety of assays, as an in vitro model for wound healing. To do this, animal tissues will be decellularised using chemical, biological and mechanical means to produce an extracellular matrix (ECM) which can then be cast into a hydrogel containing carbon nanotubes (CNTs). The CNTs allow the hydrogels to become much more conductive allowing for modulation of varying types of electrical stimuli, including electric fields and ionic/faradaic currents. Various cell types involved in wound healing, seeded within or on top of the hydrogel, will then be exposed to these stimuli at varying voltages to assess the differences in terms of wound healing characteristics.
University of NottinghamUniversity Park Nottingham, NG7 2RD
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