This lab rotation will involve:
Our hypothesis is that vape users will show adaptive behaviour toward vape-paired stimuli.
Demonstration of associative learning (Pavlovian conditioning) in vape users. One novel flavour will be paired with nicotine and a second novel flavour will be vaped but will be paired with lower strength nicotine. Behavioural differences in response to the high and low dose flavours will indicate learning.
Measures of responses to vape flavours may include a subjective report of nicotine craving, heartrate changes; galvanic skill conductance changes and EEG. Visual analogues of the procedure will pair unflavoured vape-delivered nicotine with one novel computer-presented image and a control image with a lower nicotine dose. Measures of responses to images will include those for vape flavours and also biases in looking toward nicotine-paired images over control images.
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