Biotechnology and Biological Sciences Doctoral Training Programme

Molecules, Cells and Organisms projects


Please note that the list of projects available will be increased over the next few weeks so please check frequently. Project details may also be subject to change before September 2018.


BBSRC Doctoral Training Partnerships




View all Molecules, Cells and Organisms projects

MicroRNA regulation in the inflammatory response

This project aims to understand miRNA regulation in the context of the inflammatory response, in which cells rapidly switch on the production of many mRNAs that encode inflammatory proteins.

Investigating the differential regulation of cell surface GAG in breast cancer: Using NGPD to isolate cancer cell specific peptides

In this project, we propose to identify cell-type specific variants in breast cancer patient samples in a high-throughput manner using phage display-libraries (1010 phage) of GET peptides and next-generation sequencing (NGS) in a process called next generation phage display (NGPD).

Molecular approaches to understanding allosteric modulation at the M1 Muscarinic Acetylcholine Receptor (mAChR)

This chemical biology-focused project will span the disciplines of synthetic chemistry and pharmacology to increase our understanding of the M1 mAChR. With increasing numbers of allosteric ligands being discovered for the wider G protein-coupled receptor family, the results will be of direct relevance to many other important receptors.

A ligand-guided strategy for fluorescent labelling of native cellular receptors

We have an internationally recognized track record in the design, synthesis and application of fluorescently conjugated G-Protein Coupled Receptor (GPCR) ligands. The hypothesis behind this project takes this concept and extends it to the design of molecules capable of covalently transferring a fluorescent cargo to a region of a GPCR distal to the ligand-binding site.
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Biotechnology and Biological Sciences Doctoral Training Programme

The University of Nottingham
University Park
Nottingham, NG7 2RD

Tel: +44 (0) 115 8466946