Biotechnology and Biological Sciences Doctoral Training Programme
   
   
  

Molecules, Cells and Organisms projects

 

Please note that the list of projects available will be increased over the next few weeks so please check frequently. Project details may also be subject to change before September 2018.

 

BBSRC Doctoral Training Partnerships

 

 

 

View all Molecules, Cells and Organisms projects

EGFR under stress – understanding gene expression in health and disease.

Description
The project will use a combination of standard molecular biology tools (e.g. PCR, western analysis, microscopy, cloning, cell culture, RNA/DNA manipulations, gene expression analysis) alongside more technically adventurous techniques such as polysome profiling and bioinformatic analysis.

Transcription factor regulation by ubiquitination – molecular basis of how to activate or deactivate

Description
We will use structural biology tools to investigate the effect of mono-ubiquitination on the structure and interactions using biochemical and biophysical methods. In a second line of investigation we will characterise the interaction with the deubiquitinating enzyme USP17

Generation and characterisation of different human macrophage subsets using magnetic cell sorting, fluorescent microscopy and ELSIA

Description
Generation and characterisation of different human macrophage subsets using magnetic cell sorting, fluorescent microscopy and ELSIA

Global metabolite profiling of different human macrophage subsets using advanced metabolomics methods

Description
By applying advanced analytical tools we can gain improved understanding into the cellular response of macrophages and ultimately immune response. The project can also underpin the development of new tools for immune modulation in addition to enhanced understanding of biological mechanisms of macrophage behaviour.

Generation and characterisation of nanoparticles with different size and shape

Description
By applying advanced analytical tools we can gain improved understanding into the cellular response of macrophages and ultimately immune response. The project can also underpin the development of new tools for immune modulation in addition to enhanced understanding of biological mechanisms of macrophage behaviour.
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Biotechnology and Biological Sciences Doctoral Training Programme

The University of Nottingham
University Park
Nottingham, NG7 2RD

Tel: +44 (0) 115 8466946
Email: bbdtp@nottingham.ac.uk