I received my PhD in neuroscience from McGill University in 2004. That year I also received a Marie Curie Fellowship from the EU to conduct post-doctoral research in the School of Biomedical Sciences (now School of Life Sciences) here at the University of Nottingham. In 2006 I received a Young Investigator Award from NARSAD (now Brain & Behavior Research Foundation) to continue this work. After a brief spell lecturing at De Montfort University I returned to Nottingham in 2008 to become a Lecturer in Neuroscience in the School of Biosciences at Sutton Bonington Campus. In 2018 I became an Associate Professor of Neuroscience.
In my lab we use rodent behavioural testing, systemic and central drug administration, and in vivo electrophysiology to record neuronal activity in freely behaving rodents.
I supervise final year undergraduate dissertations and I teach on various undergraduate modules in the School of Biosciences: Coordinated Physiological Functions (module convenor), Animal Biology… read more
Our research group is investigating the neurobiological basis of fear memory processing. Most recently this research has been funded by the University of Nottingham, the Biotechnology and Biological… read more
WARREN, WILLIAM G., PAPAGIANNI, ELENI P., STEVENSON, CARL W. and STUBBENDORFF, CHRISTINE, 2022. In it together? The case for endocannabinoid-noradrenergic interactions in fear extinction European Journal of Neuroscience. 55, 952-970 WILLIAMS SA, GWILT M, HOCK R, TAYLOR C, LOAYZA J, STEVENSON CW, CASSADAY HJ and BAST T, 2022. Hippocampal disinhibition reduces contextual and elemental fear conditioning while sparing the acquisition of latent inhibition eNeuro. 9(1), ENEURO.0270-21.2021
O'SULLIVAN SE, STEVENSON CW and LAVIOLETTE SR, 2021. Could Cannabidiol Be a Treatment for Coronavirus
Disease-19-Related Anxiety Disorders? Cannabis and Cannabinoid Research. 6, 7-18
Review Editor, Frontiers in Behavioural Neuroscience - Pathological Conditions
Local Group Representative for the British Neuroscience Association
Ad hoc reviewer for various journals and funding bodies nationally and internationally
I supervise final year undergraduate dissertations and I teach on various undergraduate modules in the School of Biosciences: Coordinated Physiological Functions (module convenor), Animal Biology (module convenor), Introductory Physiology, Physiology of Electrically Excitable Tissues, and Systems Neurophysiology.
Our research group is investigating the neurobiological basis of fear memory processing. Most recently this research has been funded by the University of Nottingham, the Biotechnology and Biological Sciences Research Council (BBSRC), and our industrial partners (Autifony Therapeutics, Artelo Biosciences). We have conducted this work in collaboration with various local, national and international research groups:
Role of dopamine in fear memory encoding, with Dr Bast, Prof Cassaday (both School of Psychology), Dr Voigt (School of Veterinary Medicine & Science), Dr Lee (University of Birmingham, UK), and Dr Martin (University of Dundee)
Sex differences in learned fear inhibition and associated neural circuitry, with Dr Halliday (University of York, UK) and Dr Bredy (Queensland Brain Institute, Australia)
Computational modeling of neural circuit function underlying fear memory processing, with Prof Coombes and Dr O'Dea (School of Mathematical Sciences)
Role of cannabidiol in regulating learned fear inhibition and its associated neural circuitry, with Dr Lee (University of Birmingham, UK), Prof Guimaraes (University of Sao Paulo, Brazil), and Prof Bertoglio (University of Santa Catarina, Brazil)
My doctoral research investigated central dopamine system interactions in brain regions involved in cognition and emotion. Dopamine plays an important role in various aspects of behaviour and altered dopamine transmission is involved in the pathophysiology of psychiatric disease. I examined the relationship between dopamine neurotransmission in different brain areas in response to stress and during various types of cognitive processing.
My post-doctoral research investigated the 'programming' of later cognition, emotion and brain function by the early rearing environment. Early adversity increases the risk of developing psychiatric disease later in life. Early life is a crucial time for nervous system development and insults during this critical period can permanently alter brain function and behaviour. I examined the effects of early life stress on later emotional memory processing and brain function in areas involved in cognition and emotion.