Centre for Biomolecular Sciences

Equipment & Expertise

Please find below a list of the current equipment expertise within the Centre for Biomolecular Sciences.  If you have any additions or amendments please email Huw Williams.

Chemistry NMR Spectrometer
Bruker Avance 600MHz
Configuration 1: 1H/13C /15N/2H (simultaneously)
Configuration 2: 1H/2H & X
(Tunable from 31P to 15N including 13C)
Sample Probe:
Configuration 1: Triple resonance
Probe: TXI z-gradients (Triple Resonance inverse)
Configuration 2: Inverse detection
Probe: BBI, z-gradients (Broadband inverse)
Mode of Operation: Access to trained research staff
Special Features: Pulse field gradients,
2x Broadband amplifiers,
1x 2H amp and 1x 1H amp allows complicated multi-nuclear acquisition
* Structural determination of biological macromolecules
(Protein, DNA, RNA),
* Ligand Interactions
Dr Huw Williams
Ext: 32526
Life Sciences Zeiss LSM 700 Confocal Laser Scanning Microscope 4 Excitation lasers (405nm, 488nm, 561nm and 639nm), two classical Photomultiplier tubes (PMT) detectors with 5x, 10x, 20x, 40x, 63x and 100x objective lens

1. Class II laboratories;

2. Confocal imaging of live/fixed cells;

3. 3D confocal image reconstruction;

4: fluorescent experiments such as FRET, FRAP and image quantification. 6: Live-cell, multi-channel time-lapse imaging of cultured cells or fluorescence/GFP-tagged novel molecules.

Dr Steve Atkinson Ext: 67954

Life Sciences Super Resolution Microscope

The Centre for Biomolecular Sciences will be hosting from April 2014 a Super Resolution Microscope facility in a Class 2 laboratory. The facility has been funded through an ALERT13 grant from BBSRC led by Prof Miguel Camara with additional support from the University of Nottingham and the School of Life Sciences.

The microscope will be available for Class 1 and 2 work for any researchers within the University of Nottingham and outside.

The microscope purchased is the ELYRA PS.1 super resolution system from Zeiss which offers super resolution structured illumination microscopy (SR-SIM) and single molecule localisation techniques (PALM & dSTORM). The microscope stand also has an LSM 780 confocal microscope attached.

Further information can be found here.

Details of booking and training will be available soon.

Advanced Microscopy Unit

Centre for Biomolecular Sciences

University of Nottingham
University Park
Nottingham, NG7 2RD

telephone: +44 (0) 115 846 8001
fax: +44 (0) 115 846 8002
email: CBS Enquiries