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Research Associate/Fellow - Synthetic Biologist/Molecular Biologist (2 Posts)

Reference
MED141817X2
Closing Date
Wednesday, 6th December 2017
Job Type
Research
Department
Life Sciences
Salary
£26495 to £38833 per annum, depending on skills and experience (minimum £29799 with relevant PhD). Salary progression beyond this scale is subject to performance

The Synthetic Biology Research Centre (SBRC) at the University of Nottingham is seeking a creative and motivated metabolic engineering scientist and/or synthetic biologist to work on developing gas-fermenting microbial chassis for sustainable bio-production of chemicals and fuels.

The aim of these posts is to provide metabolic engineering and molecular biology research support in the creation and exploitation of anaerobic (one post) and aerobic (second post) gas fermenting microbial chassis for the sustainable production of chemicals and fuels.The post will form part of the ‘wet-lab based’ team tasked with the experimental formulation, iterative testing and exploitation of gas fermenting chassis. There will be close interaction with other members of the multidisciplinary team, particularly the dry scientists responsible for in silico modelling and the iterative design and analysis of the chassis to fast-track the metabolic engineering of the chassis.

The SBRC-Nottingham, established by BBSRC/EPSRC with more than £14 million funding, is working at the frontiers of UK academic and industrial research with the aim of accelerating the application of Engineering and Synthetic Biology technologies to directly capture carbon by exploiting the ability of autotrophic bacteria to fix C1-gases (carbon dioxide, carbon monoxide or methane) and convert them into platform chemicals such as hydrocarbons (e.g. ethylene and isoprene), carboxylic acids (e.g. 3-hydroxypropionic acid) and others. Gas-fermenting aerobic (e.g., Cupriavidis necator) and anaerobic (e.g., Acetogens) bacterial chassis are being used as primary engineering platforms. 

The role holder will join the Centre that is equipped with state of art facilities including laboratory suites dedicated to multiplexed gas fermentation, high-throughput robotics and analytics (HPLC, GC, GC-MS, LC-MS-MS). A unique, interdisciplinary research environment of SBRC will provide opportunity to work and collaborate with researchers who have expertise in sciences supporting Synthetic Biology, including molecular biology and microbiology, chemistry and engineering, computer science and systems biology.

Candidate should hold a PhD (pending or awarded) in a discipline relevant to microbial strain engineering involving for example, systems biology, metabolic flux analysis or synthetic biology. Past experience in metabolic engineering or/and synthetic biology of microbial species is essential. A knowledge of advanced genome editing, high-throughput -omics techniques and/or metabolic pathway analysis would be desirable.

This full-time fixed-term post is available immediately until 30 July 2019.

Informal enquiries may be addressed to Professor Nigel P Minton nigel.minton@nottingham.ac.ukPlease note that applications sent directly to this Email address will not be accepted.

The School of Life Sciences holds an Athena Silver SWAN Award, in recognition of our commitment to supporting and advancing women’s careers in the life sciences (STEMM). You can read more about this initiative at http://www.nottingham.ac.uk/life-sciences/documents/athena-swan-silver-award.pdf

The University of Nottingham is an equal opportunities employer and welcomes applications from all sections of the community.