School of Life Sciences
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Our research focuses on understanding the molecular and genetic basis of microbial physiology and using this knowledge to engineer strains that have practical applications in the real-world.

The range of microbes under investigation include:

  • anaerobic Clostridium (pathogens and industrial strains)
  • thermophilic bacilli
  • autotrophic bacteria (anaerobes and aerobes)
  • methane-utilising bacteria
  • yeast and filamentous fungi

Embedded within the theme is the BBSRC/EPSRC Synthetic Biology Research Centre (SBRC), which collaborates on experimentalists and modellers with the Centre for Biomolecular Sciences (CBS).

SBRC Amend

Microbial Engineering



Our research has real-world impact on healthcare, the environment and produce. Examples of this are:

  • new sustainable routes to the production of chemicals and fuels
  • reducing Green House Gas emission
  • developing new food products based on natural processes
  • new treatments for disease, including cancer

Principal investigators

Professor Simon Avery

Effects of environmental toxicants (eg metals and antimicrobials) on cells

Dr Matthias Brock

Filamentous fungi and yeasts

Dr Alan Cockayne

Metal ion uptake systems in staphylococci and clostridium difficile

Professor Paul Dyer

Sexual reproduction in fungi

Professor Nigel Minton
(Academic Lead)

Engineering of bacterial chassis of medical and industrial importance

Dr Klaus Winzer

Bacterial physiology and metabolism

Dr Ying Zhang

Metabolic engineering of microbial chassis for chemical and fuel production



School of Life Sciences

University of Nottingham
Medical School
Queen's Medical Centre
Nottingham NG7 2UH

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