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Dimitris Kalogiros

Research Fellow in Mathematical Biology and Medicine (Research & Teaching) / AFHEA / MHFA, Faculty of Science

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Biography

Dimitris was awarded a Bsc in Applied Mathematics and Physics from the National University of Technology in Athens (Greece) before completing his Msc in Applied Mathematical Sciences with Biological and Ecological Modelling at Heriot-Watt University in Edinburgh, Scotland. During his studies, he learned a broad range of topics in the areas of mathematical modelling, mathematical ecology, mathematical biology and medicine, dynamical systems, applied linear algebra, numerical analysis, regression analysis, linear models and designs, computer science along with their applications in physics and engineering.

In late 2012 Dimitris joined the University of Dundee and The James Hutton Institute to undertake a PhD in mathematical modelling of plant root systems funded by the European project EURoot (http://www.euroot.eu/).

After completing his PhD, Dimitris joined the School of Mathematical Sciences at the University of Nottingham in order to work on a Wellcome Trust-funded Collaborative Award entitled "Integrative Transport Phenomena in Chemokine Gradient Establishment" under the supervision of Dr. Bindi Brook in collaboration with Prof. James Moore at the Imperial College London and Prof. Robert Nibbs at the University of Glasgow. This research programme will lead to a deeper understanding of critical immunological processes that contribute to protection from infection, facilitate responses to vaccination and drive pathology in a broad spectrum of diseases. The implications in health and disease are therefore substantial and this study could aid the development of new immunoengineered therapies involving chemokine gradient manipulation.

Expertise Summary

Areas of research and teaching interest: mathematical modelling, mathematical ecology, mathematical biology and medicine, dynamical systems, applied linear algebra, numerical analysis, regression analysis, linear models and designs, computer science along with their applications in physics and engineering. PDE/SDE modelling, numerical analysis, optimisation, application of PDEs to image analysis, image analysis pipelines, computer programming

Teaching Summary

Dimitris is an Associate Fellow of the Higher Education Academy and a Mental Health First Aider (MHFA England). He is actively involved in teaching, student support and development at the University… read more

Research Summary

Dimitris is currently working on a Wellcome Trust-funded Collaborative Award entitled "Integrative Transport Phenomena in Chemokine Gradient Establishment" under the supervision of Dr. Bindi Brook in… read more

Recent Publications

Dimitris is an Associate Fellow of the Higher Education Academy and a Mental Health First Aider (MHFA England). He is actively involved in teaching, student support and development at the University of Nottingham. He is also part of the student mentoring programme at Heriot-Watt University in Edinburgh, Scotland.He has been responsible for the supervision of undergraduate students through their course projects. He also mentored final year undergraduate Engineering students and assisted the preparation and delivery of undergraduate Mathematics lectures, tutorials and computer lab workshops.

He is also really interested in different approaches to teaching Mathematics as well as in public engagement events about science and interdisciplinary research in Mathematics aimed at students and to the public. Some of his personal projects include:

  • "Rootie, the Robin Root on the m-aRt-hS Planet"
  • "LEMMAs: Language - Etymology - Mathematics Meanderings through Art and Science"

For more information, please visit https://uk.linkedin.com/in/dimitrisioanniskalogiros

Current Research

Dimitris is currently working on a Wellcome Trust-funded Collaborative Award entitled "Integrative Transport Phenomena in Chemokine Gradient Establishment" under the supervision of Dr. Bindi Brook in collaboration with Prof. James Moore at the Imperial College London and Prof. Robert Nibbs at the University of Glasgow. The principal goal of the project is to develop a comprehensive quantitative knowledge base of chemokine gradient formation and regulation using integrated experimental and modelling approaches. Chemokines are secreted chemoattractants that orchestrate the migration and positioning of leukocytes, and are indispensable components of all protective and pathogenic immune and inflammatory responses. A combination of diffusion, advection, binding kinetics and cellular uptake result in the generation of spatial chemokine gradients that govern leukocyte migration. If chemokine gradients are not appropriately tuned, leukocytes fail to respond and immune responses are compromised. This multidisciplinary project will provide unprecedented insight into this complex, dynamic and critically important process, and has potential impact on vaccination and on the treatment of diseases with key immune cell contributions, such as allergy, autoimmunity, cardiovascular disease, and cancer.

Past Research

In the past, Dimitris worked on the development and application of novel mathematical and computational methods in modelling of neurons as well as plant root systems. Innovative mathematical techniques in numerical simulation, model parameterisation and model sensitivity analysis were used to calibrate root growth density-based models on various genotypes in a range of reference environmental conditions. Results from this work on PDE modelling, numerical analysis, optimisation, application of PDEs to image analysis, image analysis pipelines, computer programming and plant image analysis software aimed to uncover key biological factors and plant traits that can be targeted by breeding.

School of Mathematical Sciences

The University of Nottingham
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Nottingham, NG7 2RD

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