I have been a Consultant Paediatric oncologist with clinical expertise in paediatric solid tumours and brain tumours in Nottingham since 2016 and was appointed as Clinical Associate Professor at the University of Nottingham in March 2019.
I completed my medical degree in India in 2002 and moved to the UK where i trained to become a paediatric oncologist. I obtained my PhD in 2012 in cancer cell signalling from the University of Dundee investigating the interplay between cellular metabolism and chemotherapy induced DNA damage. I have developed a research niche in tumour metabolism, particularly in childhood brain and liver tumours and lead a research group within the Children's Brain tumour research centre . I have written clinical trials including PHITT (Paediatric Hepatic International Tumour Trial) and I am co-Investigator on this study. I am a member of the SIOPEL (International Society of Paediatric Oncology Liver group) and on the SIOP Scientific Advisory board for liver tumours. I am the NIHR CRN lead for Paediatric Oncology in the East Midlands and Principal Investigator on several clinical trials. My career aim is to develop novel therapies for children with cancer and to improve outcomes for children with cancer in developing countries.
Lead for Undegraduate paediatrics - BMBS course
Interim FiY1 lead May-Aug 2020
MSc Oncology supervisor since 2018
MSc CIB supervisor since 2019
Open to self funding PhDs
CCLG Little Princess Project Grant -£96,445- Aug 2019- July 2021. Exploring alterations in amino acid metabolism as novel therapeutic targets in paediatric glial tumours using advanced metabolomics methods
University Of Nottingham International collaboration fund- £ 5000- Jan 2020- Dec 2020- Promoting early diagnosis of brain tumours children in South India
Using CSF Biomarkers to detect minimal residual disease in ependymoma
Co-investigator of the international PHITT study with Professor Morland, Birmingham
Investigating the metabolome of hepatoblastoma- collaboration with Carolina Armengol, Spain
International hepatoblastoma relapse registry-UK lead
Promoting early diagnosis of brain tumours in India
Investigating the arginine auxotrophy of childhood brain tumours
Investigating the AMPK pathway in cancer and DNA damage
Plans to expand metabolomics based research in low grade glioma and medulloblastoma
Translational projects using metabolomic approaches to effect suppression of tumour growth and recurrence.
Improving early diagnosis of abdominal tumours in the UK