Contact

• workRoom 3018
  Royal Derby Hospital
  Uttoxeter Road
  Derby
  DE22 3DT
  UK
• imti.choonara@nottingham.ac.uk

Biography

Imti Choonara is one of the leading paediatric clinical pharmacologists in the world. He has been involved in ensuring that paediatric clinical pharmacology is an accredited subspecialty of paediatrics in the UK. He is Editor in Chief of the open access journal BMJ Paediatrics Open.

His research interests include drug toxicity, clinical trials, rational use of medicines, epidemiology of the use of medicines, inequalities in child health and access to medicines in children. He is interested in international child health and organises an annual workshop in Child health in Cuba. Despite recently retiring, he is still active in research and supervising postgraduate students, as an Emeritus Professor in Child Health at the University of Nottingham.

Expertise Summary

Paediatric clinical pharmacology

Research Summary

Drug toxicity in children

Rational use of medicines in children

Recent Publications

• ZENG L, HU D, CHOONARA I, MU D, ZHANG L, LI X, ZHANG Z, HU Z and QUAN S, 2017. A prospective study of the use of antibiotics in the Emergency Department of a Chinese University Hospital. Int J Pharm Pract. 25(1), 89-92
• ALJEBAB F, CHOONARA I and CONROY S, 2017. Systematic review of the toxicity of long-course oral corticosteroids in children. PLOS One. 12(1), e0170259
• ZENG L, CHOONARA I, ZHANG L, LI Y and SHI J, 2017. Effectiveness of prothrombin complex concentrate (PCC) in neonates and infants with bleeding or risk of bleeding: a systematic review and meta-analysis. Eur J Pediatrics. 176(5), 581-589
• CHOONARA I, 2017. Child health: what should be done? BMJ Paediatrics Open. 1, e000001

• View all publications

Future Research

Access to medicines by children

• ZENG L, HU D, CHOONARA I, MU D, ZHANG L, LI X, ZHANG Z, HU Z and QUAN S, 2017. A prospective study of the use of antibiotics in the Emergency Department of a Chinese University Hospital. Int J Pharm Pract. 25(1), 89-92
• ALJEBAB F, CHOONARA I and CONROY S, 2017. Systematic review of the toxicity of long-course oral corticosteroids in children. PLOS One. 12(1), e0170259
• ZENG L, CHOONARA I, ZHANG L, LI Y and SHI J, 2017. Effectiveness of prothrombin complex concentrate (PCC) in neonates and infants with bleeding or risk of bleeding: a systematic review and meta-analysis. Eur J Pediatrics. 176(5), 581-589
• CHOONARA I, 2017. Child health: what should be done? BMJ Paediatrics Open. 1, e000001
• SAMMONS HM and CHOONARA I, 2017. Substandard medicines: a greater problem than counterfeit medicines? BMJ Paediatrics Open. 1, e000007
• EGUNSOLA O, STAR K, JUHLIN K, KARDAUN SH, CHOONARA I and SAMMONS HM, 2017. Retrospective review of paediatric case reports of Stevens-Johnson syndrome and toxic epidermal necrolysis with lamotrigine from an international pharmacovigilance database. BMJ Paediatrics Open. e000039
• PAPPACHAN B and CHOONARA I, 2017. Inequalities in child health in India BMJ Paediatrics Open. e000054
• EGUNSOLA O, SAMMONS HM, OJHA S, WHITEHOUSE W, ANDERSON M, HAWCUTT D and CHOONARA I, 2017. Protocol for a prospective observational study of adverse drug reactions of antiepileptic drugs in children in the UK. BMJ Paediatrics Open. e000116
• OJHA S and CHOONARA I, 2017. Medication errors in infants at home. Arch Dis Child. 313007
• EGUNSOLA O, CHOONARA I and SAMMONS HM, 2017. Anti-epileptic drug utilisation in paediatrics: a systematic review. BMJ Paediatrics Open. e000088
• PRITCHARD E and CHOONARA I, 2017. Armed conflict and child mental health. BMJ Paediatrics Open. e000087
• ALJEBAB F, CHOONARA I and CONROY S, 2016. Systematic review of the toxicity of short-course oral corticosteroids in children Archives of Disease in Childhood. 101, 365-370
• CLIFF-ERIBO K, SAMMONS H, STAR K, EDWARDS IR, OSAKWE A and CHOONARA I, 2016. Adverse drug reactions in Nigerian children: a retrospective review of reports submitted to the Nigerian Pharmacovigilance Centre from 2005 to 2012. Paediatr Int Child Health. 36(4), 300-304
• SAMMONS H and CHOONARA I, 2016. Learning Lessons from Adverse Drug Reactions in Children. Children (Basel). 3(1),
• TAMBE P, SAMMONS HM and CHOONARA I, 2016. Child mortality of children aged 5-15 years in the UK and Sweden: a comparison Arch Dis Child. 101(4), 409-410
• EGUNSOLA O, CHOONARA I and SAMMONS HM, 2016. Safety of levetiracetam in paediatrics: a systematic review. PLoS One. 11(3), e0149686
• CHOONARA I and STAR K, 2016. Levetiracetam and impaired renal function. WHO Pharmaceutical Newsletter. 18-23
• ALLEGAERT K and CHOONARA I, 2016. All medicines have side effects. Arch Dis Child. 101(10), 951-952
• ALTAMIMI M, CHOONARA I and SAMMONS HM, 2016. Invasiveness of pharmacokinetic studies in children: a systematic review. BMJ Open. 6(7), e010484
• BONATI M, JACQZ-AIGRAIN E and CHOONARA I, 2016. Licensed medicines, off-label use or evidence-based. Which is most important? Arch Dis Child. 102(1), 53-54
• CLIFF-ERIBO KO, SAMMONS H and CHOONARA I, 2016. Systematic review of paediatric studies of adverse drug reactions from pharmacovigilance databases. Expert Opinion on Drug Safety. 15(10), 1321-1328
• CASTELLÓ GONZÁLEZ M, PONS VÁSQUEZ R, RODRIGUEZ BENCOMO D and CHOONARA I, 2016. International Medical Collaboration: Lessons from Cuba. Children (Basel). 3(4), 20
• STARKEY E, CHOONARA I and SAMMONS H, 2016. Pharmacology and therapeutics.. In: LISSAUER T and CARROLL W, eds., The Science of Paediatrics: MRCPCH Mastercourse. 1. Elsevier. 687-702
• ESCOBEDO AA, DE ARMAS Y, MCINTYRE J and CHOONARA I, 2016. La Habana 2016 - Workshop on writing scientific papers. Bibliotecas Anales de Investigación. 12(1), 147-148
• OSHIKOYA KA, SMITH K, SAMMONS H and CHOONARA I, 2015. Decreased metabolism of 13C-caffeine via hepatic CYP1A2 in marasmus and kwashiorkor based on breath test. J Basic Clin Physiol Pharmacol. 26(1), 105-113
• STAR K and CHOONARA I, 2015. How safe is paracetamol? Arch Dis Child. 100, 73-74
• ALTAMIMI M, SAMMONS H and CHOONARA I, 2015. Inter-individual variation in midazolam clearance in children. Arch Dis Child. 100, 95-100
• ROMERO REYNO J, CASTELLO GONZALEZ M and CHOONARA I, 2015. Child health in Central America and the Caribbean Arch Dis Child. 100, s70-s71
• CHOONARA I, 2015. Reputable publishers and transparency about profits. The BMJ. 350, h708
• ALTAMIMI M, CHOONARA I and SAMMONS H, 2015. Inter-individual variation in morphine clearance in children. Eur J Clin Pharmacol. 71, 649-655
• ANDERSON M, EGUNSOLA O, CHERRILL J, CHERRILL J, MILWARD C, FAKIS A and CHOONARA I, 2015. Anderson M, Egunsola O, Cherrill J, Millward C, Fakis A, Choonara I. A prospective study of adverse drug reactions in antiepileptic drugs in children. BMJ Open. 5, e008298
• EGUNSOLA O, CHOONARA I and SAMMONS H, 2015. Safety of lamotrigine in paediatrics: a systematic review. BMJ Open. e007711
• OSHIKOYA K, SAMMONS H, SMITH K and CHOONARA I, 2015. Lack of a significant change in caffeine metabolism in underweight children as determined by the caffeine breath test. Arch Dis Child. 100, 689-693
• TAMBE P, SAMMONS H and CHOONARA I, 2015. Why do young children die in the UK? A comparison with Sweden. Arch Dis Child. 100, 928-931
• CLIFF-ERIBO KO, CHOONARA I, DODOO A, DARKO DM and SAMMONS HM, 2015. Adverse drug reactions in Ghanaian children: review of reports from 2000-2012 in VigiBase Expert Opin Drug Saf. 14(12), 1827-1833
• SMITH C, EGUNSOLA O, CHOONARA I, KOTECHA S and JACQZ-AIGRAIN E, 2015. Use and safety of azithromycin in neonates: a systematic review BMJ Open. 5(12), e008194
• ALMUZAINI T, SAMMONS H and CHOONARA I, 2015. Falsified and substandard medicines.. In: MACLEOD S, HILL S, KOREN G and RANE A, eds., Optimizing Treatment for Children in the Developing World. 1. Springer ADIS. 81-95
• ALSULAMI Z, CHOONARA I and CONROY S, 2014. Nurses' knowledge about the double-checking process for medicines administration. Nursing children and young people. 26(9), 21-6
• CHOONARA I, 2014. Why children do not receive treatment. Arch Dis Child. 99(7), 605-606
• RAJMIL L, FERNANDEZ DE SANMAMED M-J, CHOONARA I and FARESJO T, 2014. Impact of the 2008 economic and financial crisis on child health: a systematic review. Int J Environ Res Public Health. 11(6), 6528-6546
• PANSIERI C, BONATI M, CHOONARA I and JACQZ=AIGRAIN E, 2014. Neonatal drug trials: impact of EU and US paediatric regulations. Arch Dis Child Fetal Neonatal. 99(5), F428
• CHOONARA I, 2014. Paediatric research environment in the UK. Paediatrics and Child Health. 24(8), 370-373
• CHOONARA I and SAMMONS H, 2014. Paediatric clinical pharmacology in the UK Arch Dis Child. 99, 1143-1146
• STAR K, EDWARDS IR and CHOONARA I, 2014. Valproic Acid and Fatalities in children. A review of individual case safety reports in VigiBase. PlosOne.
• ALMUZAINI T, SAMMONS H and CHOONARA I, 2014. Quality of medicines in Canada: a retrospective review of risk communication documents (2005–2013). BMJ Open.
• ALKAHTANI S, CHERRILL J, MILLWARD C, GRAYSON K, HILLIAM R, SAMMONS H and CHOONARA I, 2014. Access to medicines by child refugees in the East Midlands region of England: a cross-sectional study. BMJ Open. 4(12), e006421