Contact

• workClinical Sciences Wing, The Medical School
  Royal Derby Hospital
  Uttoxeter Road
  Derby
  DE22 3DT
  UK
• work01332 724 694
• fax01332 724 697
• jon.lund@nottingham.ac.uk
• https://itunes.apple.com/gb/podcast/school-of-surgery/id642197143?mt=2

Expertise Summary

Coloproctology

prehabilitiation and exercise interventions to improve outcomes

pilonidal sinus

surgical training

surgical emergencies

Teaching Summary

Undergraduate medical education.

Post graduate training in General Surgery.

www.learncolorectalsurgery.com

School of Surgery https://itunes.apple.com/gb/podcast/school-of-surgery/id642197143?mt=2

https://www.youtube.com/channel/UCHgorCu13L7iXGpVv1yfBCQ

Research Summary

Novel treatments for pilonidal sinus

Treatment of anal fissure

Improving outcomes in elderly patients having surgery

Role of Micro RNAs in colorectal cancer

Endocannabinoids in gut permiability

Selected Publications

• CRUICKSHANKS, H.A., VAFADAR-ISFAHANI, N., DUNICAN, D.S., LEE, A., SPROUL, D., LUND, J.N, MEEHAN, R.R. and TUFARELLI, C., 2013. Expression of a large LINE-1 driven antisense RNA is linked to epigenetic silencing of the metastasis suppressor gene TFPI-2 in cancer Nucleic Acids Research. 41(14), 6857-6869
• PEACOCK O, CLAYTON S, ATKINSON F, TIERNEY GM and LUND JN, 2013. "Be Clear on Cancer." The impact of the UK national bowel cancer awareness campaign. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. (In Press.)
• MITCHELL WK, LUND JN and WILLIAMS JP, 2013. The role of carbohydrate drinks in preoperative nutrition. Comment 2. Annals of the Royal College of Surgeons of England. 95(1), 82-3
• WATTS ES, PEACOCK O, GUPTA A, SPEAKE WJ and LUND JN, 2013. Anyone for TAMIS? Techniques in coloproctology. 17(2), 253-5

• View all publications

Past Research

1st randomized trail of topical GTN in the treatment of chronic anal fissure. This work, published in The Lancet, set a new paradigm in the treatment of this common condition, and became first line treatment world wide.

Future Research

A multicentre, international radomised trail of the role of topical diltazem in the treatmetn of chronic anal fissure. (currently finished recruitment and awaiting completion of data collection).

• HARDY, EDWARD J., HATT, JACOB, DOLEMAN, BRETT, SMART, THOMAS F., PIASECKI, MATTHEW, LUND, JONATHAN N. and PHILLIPS, BETHAN E., 2022. Post-operative electrical muscle stimulation attenuates loss of muscle mass and function following major abdominal surgery in older adults: a split body randomised control trial AGE AND AGEING. 51(10),
• SMART TFF, DOLEMAN B, HATT J, PAUL M, TOFT S, LUND JN and PHILLIPS BE, 2022. The role of resistance exercise training for improving cardiorespiratory fitness in healthy older adults: a systematic review and meta-analysis Age Ageing. 51(6), afac143
• HERROD PJ, DOLEMAN B, HARDY P, MALONEY T, WILLIAMS JP and LUND JN, 2022. Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal pilonidal sinus Cochrane Database Syst Rev. 5(5), CD013439
• HOPE C, LUND J, GRIFFITHS G and HUMES D, 2022. Differences in progression by surgical specialty: a national cohort study BMJ Open. 12(2), e053391
• HARDY EJO, INNS TB, HATT J, DOLEMAN B, BASS JJ, ATHERTON PJ, LUND JN and PHILLIPS BE, 2022. The time course of disuse muscle atrophy of the lower limb in health and disease J Cachexia, Sarcopenia Muscle. 13(6), 2616-2629
• WILLIS CRG, AMES RM, DEANE CS, PHILLIPS BE, BOEREBOOM CL, ABDULLA H, BUKHARI SSI, LUND JN, WILLIAMS JP, WILKINSON DJ, SMITH K, KADI F, SZEWCZYK NJ, ATHERTON PJ and ETHERIDGE T, 2020. Network analysis of human muscle adaptation to aging and contraction Aging (Albany NY). 12, 1
• CHAPMAN SJ, BLANCO-COLINO R, PÉREZ‐AJATES S, EUROSURG COLLABORATIVE and LUND JN, 2020. Safety of hospital discharge before return of bowel function after elective colorectal surgery Br J Surg. 107(5),
• BHANGU A, LUND JN and RIFT STUDY GROUP ON BEHALF OF WEST MIDLANDS RESEARCH COLLABORATIVE, 2020. Evaluation of appendicitis risk prediction models in adults with suspected appendicitis 107(1), 73-86
• EUROSURG COLLABORATIVE and LUND JN, 2020. Safety and efficacy of non‐steroidal anti‐inflammatory drugs to reduce ileus after colorectal surgery Br Journal of Surgery. 107(2), e161-e169
• BOYD-CARSON H, DOLEMAN B, CROMWELL D, LOCKWOOD S, WILLIAMS JP, TIERNEY GM, LUND JN, ANDERSON ID and NATIONAL EMERGENCY LAPAROTOMY AUDIT COLLABORATION, 2020. Delay in Source Control in Perforated Peptic Ulcer Leads to 6% Increased Risk of Death Per Hour: A Nationwide Cohort Study World J Surg. 44(3), 869-875
• BLACKWELL JEM, DOLEMAN B, BOEREBOOM CL, MORTON A, WILLIAMS S, ATHERTON P, SMITH K, WILLIAMS JP, PHILLIPS BE and LUND JN, 2020. High-intensity interval training produces a significant improvement in fitness in less than 31 days before surgery for urological cancer: a randomised control trial Prostate Cancer Prostatic Dis.
• DOLEMAN B, FREEMAN SC, LUND JN, WILLIAMS JP and SUTTON AJ, 2020. Funnel plots may show asymmetry in the absence of publication bias with continuous outcomes dependent on baseline risk: presentation of a new publication bias test Res Synth Methods. 11(4), 522-534
• BOYD-CARSON H, DOLEMAN B, LOCKWOOD S, WILLIAMS JP, TIERNEY GM and LUND JN, 2020. National Emergency Laparotomy Audit Collaboration.Trainee-led emergency laparotomy operating Br J Surg.
• EUROSURG COLLABORATIVE, CHAPMAN SJ, BLANCO-COLINO R, LUND JN and ET AL, 2020. Safety of hospital discharge before return of bowel function after elective colorectal surgery Br J Surg. 107(5), 552-559
• RIFT STUDY GROUP ON BEHALF OF THE WEST MIDLANDS RESEARCH COLLABORATIVE, LUND JN and ET AL, 2020. Appendicitis risk prediction models in children presenting with right iliac fossa pain (RIFT study): a prospective, multicentre validation study 4(4), P271-280
• DAS R, SINGH R, DIN S and LUND J, 2020. Therapeutic resolution of focal, predominantly anastomotic Crohn’s disease strictures using removable stents: outcomes from a single-centre United Kingdom case series Gastrointestinal Endoscopy. S0016-5107(20)30121-8
• HOPE C, REILLY JJ, GRIFFITHS G, LUND J and HUMES D, 2020. Factors Associated with Attrition and Performance Throughout Surgical Training: A Systematic Review and Meta-Analysis World J Surg. 45(2), 429-442
• HERROD PJJ, LUND JN and PHILLIPS BE, 2020. Time-efficient physical activity interventions to reduce blood pressure in older adults: a randomised controlled trial Age and Ageing. afaa211
• HERROD PJJ, BLACKWELL JEM, BOEREBOOM CL, ATHERTON PJ, WILLIAMS JP, LUND JN and PHILLIPS BE, 2020. The time course of physiological adaptations to high‐intensity interval training in older adults Aging Med (Milton). 3(4):245-251.(4), 245-251
• DEANE CS, AMES RM, PHILLIPS BE, WEEDON MN, WILLIS CRG, BOEREBOOM C, ABDULLA H, BUKHARI SSI, LUND JN, WILLIAMS JP, WILKINSON DJ, SMITH K, GALLAGHER IJ, KADI F, SZEWCZYK NJ, ATHERTON PJ and ETHERIDGE T, 2019. The acute transcriptional response to resistance exercise: impact of age and contraction mode. Aging. 11(7), 2111-2126
• BOEREBOOM CL, BLACKWELL JEM, WILLIAMS JP, PHILLIPS BE and LUND JN, 2019. Short-term pre-operative high-intensity interval training does not improve fitness of colorectal cancer patients Scand J Med Sci Sports. 29(9), 1383-1391
• KARWAD MA, COUCH DG, WRIGHT KL, TUFARELLI C, LARVIN M, LUND J and O'SULLIVAN SE, 2019. Endocannabinoids and endocannabinoid-like compounds modulate hypoxia-induced permeability in CaCo-2 cells via CB1, TRPV1, and PPARα Biochemical pharmacology. pii: S0006-2952(19)30272-2
• THOMAS PW, HERROD PJJ, HARDY EJO, SIAN TS, BLACKWELL JEM, BOYD-CARSON H and LUND JN, 2019. Recent outcomes from the use of fibrin glue in pilonidal sinus disease Coloproctology. 41(3), 211
• KEELER BD, DICKSON EA, SIMPSON JA, NG O, PADMANABHAN H, BROOKES MJ, ACHESON AG and IVICA TRIAL GROUP (LUND JN), 2019. The impact of pre‐operative intravenous iron on quality of life after colorectal cancer surgery: outcomes from the intravenous iron in colorectal cancer‐associated anaemia Anaesthesia. 74(6), 714-725
• GLASBEY JC, GLOBALSURG COLLABORATIVE, WRITING GROUP, GLASBEY JC, ADISA AO, COSTAS-CHAVARRI A and LOCAL COLLABORATORS (GLOBAL SURG-1) LUND J, 2019. Global variation in anastomosis and end colostomy formation following left‐sided colorectal resection BJS Open. 3(3), 403-414
• LEE MJ, SAYERS AE, DRAKE TM, MARRIOTT PJ, ANDERSON ID and NASBO STEERING GROUP AND NASBO COLLABORATORS (LUND J), 2019. National prospective cohort study of the burden of acute small bowel obstruction BJS Open. 3(3), 354-366
• CONSENSUS GROUP ON FELLOWSHIPS IN GENERAL SURGERY, STEERING GROUP, DATA COLLECTION, WRITING GROUP (LUND J), 2019. Structure and quality assurance of Fellowship Training in General Surgery: consensus recommendations from the Association of Surgeons in Training Int J Surg. 67, 101-106
• HARDY EJO, HERROD PJ, DOLEMAN B, PHILLIPS HG, RANAT R and LUND JN, 2019. Surgical interventions for the treatment of sacrococcygeal pilonidal sinus disease in children: a systematic review and meta-analysis J Pediatr Surg. pii: S0022-3468(19)30206-4
• BHATTACHARJEE D, DOLEMAN B, LUND J and WILLIAMS J, 2019. Mirtazapine for postoperative nausea and vomiting: systematic review, meta-analysis, and trial sequential analysis J Perianesth Nurs. 34(4), 680-690
• POTTER S, CONROY EJ, CUTRESS RI and IBRA STEERING GROUP, BREAST RECONSTRUCTION RESEARCH COLLABORATIVE (LUND J), 2019. Short-term safety outcomes of mastectomy and immediate implant-based breast reconstruction with and without mesh (iBRA): a multicentre, prospective cohort study Lancet Oncol. 20(2), 254-266
• . GLOBALSURG COLLABORATIVE (LUND JN), 2019. Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy Br J Surg. 106(2), e103-e112
• T HOSSAIN, B E PHILIPS, B DOLEMAN, J N LUND and J P WILLIAMS, 2019. A double-blind randomized controlled trial of the effects of eicosapentaenoic acid supplementation on muscle inflammation and physical function in patients undergoing colorectal cancer resection Clinical Nutrition. (In Press.)
• BROWN SR and LUND JN, 2019. The evidence base for pilonidal sinus surgery is the pits Techniques in Coloproctology. 23, 1173-1175
• NATIONAL AUDIT OF SMALL BOWEL OBSTRUCTION STEERING GROUP, NATIONAL AUDIT OF SMALL BOWEL OBSTRUCTION COLLABORATORS and LUND JN, 2019. Outcomes following small bowel obstruction due to malignancy in the national audit of small bowel obstruction Eur J Surg Onc. 45(12), P2319-2324
• HERROD PJJ, ADIAMAH A, BOYD-CARSON H, DALIYA P, EL-SHARKAWY AM, SARMAH PB, HOSSAIN T, COUCH J, SIAN TS, WRAGG A, ANDREW DR, PARSONS SL, LUND JN, LOBO DN, WES-PI STUDY GROUP ON BEHALF OF THE EAST MIDLANDS SURGICAL ACADEMIC NETWORK (EMSAN) and WES-PI STUDY GROUP, 2019. Winter cancellations of elective surgical procedures in the UK: a questionnaire survey of patients on the economic and psychological impact BMJ Open. 9(9), e028753
• THOMAS PW, BLACKWELL JEM, HERROD PJJ, PEACOCK O, SINGH R, WILLIAMS JP, HURST NG, SPEAKE WJ, BHALLA A and LUND JN, 2019. Long-term outcomes of biological mesh repair following extra levator abdominoperineal excision of the rectum: an observational study of 100 patients Tech Coloproctol. 23(8), 761-767
• LUND, J.N., SCHOLEFIELD, J.H., GRAINGE, M.J., SMITH, S.J., MANGHAM, C., ARMITAGE, N.C., ROBINSON, M.H. and LOGAN, R.F., 2001. Risks, costs, and compliance limit colorectal adenoma surveillance: lessons from a randomised trial. Gut. 49(1), 91-6