ABDULLA H, PHILLIPS B, WILKINSON D, GATES A, LIMB M, JANDOVA T, BASS J, LEWIS J, WILLIAMS J, SMITH K, IDRIS I and ATHERTON PJ, 2022. Effects of GLP-1 infusion upon whole-body glucose uptake and skeletal muscle perfusion during fed-state in older men J Clin Endocrinol Metab. dgac613 GHARAHDAGHI N, RUDRAPPA S, BROOK MS, FARRASH W, IDRIS I, ABDUL AZIZ MH, KADI F, PAPAIONNOU K, PHILLIPS BE, SIAN T, HERROD PJ, WILKINSON DJ, SZEWCZYK NJ, SMITH K and ATHERTON PJ, 2022. Pharmacological hypogonadism impairs molecular transducers of exercise-induced muscle growth in humans J Cachexia Sarcopenia Muscle. 13(2), 1134-1150 BROOK MS, STOKES T, GORISSEN SHM, BASS J, MCGLORY C, CEGIELSKI J, WILKINSON DJ, PHILLIPS BE, SMITH K, PHILLIPS SM and ATHERTON PJ, 2022. Declines in muscle protein synthesis account for short-term muscle disuse atrophy in humans in the absence of increased muscle protein breakdown J Cachexia, Sarcopenia Muscle. 13(4), 2005-2016 GUO Y, JONES EJ, INNS TB, ELY IA, STASHUK DW, WILKINSON DJ, SMITH K, PIASECKI J, PHILLIPS BE, ATHERTON PJ and PIASECKI M, 2022. Neuromuscular recruitment strategies of the vastus lateralis according to sex Acta Physiol (Oxf). 235(2), e13803 WILLIS CRG, AMES RM, DEANE CS, PHILLIPS BE, BOEREBOOM CL, ABDULLA H, BUKHARI SSI, LUND JN, WILLIAMS JP, WILKINSON DJ, SMITH K, KADI F, SZEWCZYK NJ, ATHERTON PJ and ETHERIDGE T, 2020. Network analysis of human muscle adaptation to aging and contraction Aging (Albany NY). 12, 1 JOANISSE S, ASHCROFT S, WILKINSON DJ, POLLOCK RD, O'BRIEN KA, PHILLIPS BE, SMITH K, LAZARUS NR, HARRIDGE S, ATHERTON PJ and PHILP A, 2020. High levels of physical activity in later life are associated with enhanced markers of mitochondrial metabolism J Gerontol A Biol Sci Med Sci. glaa005 DEANE CS, PHILLIPS BE, SMITH K, STEELE AM, LIBRETTO T, STATTON SA, ATHERTON PJ and ETHERIDGE T, 2020. Challenges and practical recommendations for successfully recruiting inactive, statin-free older adults to clinical trials BMC Res Notes. 13(1), 174 FARRASH W, BROOK M, CROSSLAND H, PHILLIPS BE, CEGIELSKI J, WILKINSON DJ, CONSTANTIN-TEODOSIU D, GREENHAFF PL, SMITH K, CLEASBY M and ATHERTON PJ, 2020. Impacts of rat hind-limb Fndc5/Irisin overexpression upon muscle and adipose tissue metabolism Am J Physiol Endocrinol Metab: 318(6):E943-E955. 318(6), E943-£955 DAVIES RW, BASS JJ, CARSON BP, NORTON C, KOZIOR M, WILKINSON DJ, BROOK MS, ATHERTON PJ, SMITH K and JAKEMAN PM, 2020. The Effect of Whey Protein Supplementation on Myofibrillar Protein Synthesis and Performance Recovery in Resistance-Trained Men Nutrients. 12(3), 845 MILLER BF, REID JJ, PRICE JC, LIN HL, ATHERTON PJ and SMITH K, 2020. CORP: The use of deuterated water for the measurement of protein synthesis J Appl Physiol (1985). 128(5), 1163-1176 ABDULLA H, PHILLIPS BE, WILKINSON DJ, LIMB M, JANDOVA T, BASS JJ, RANKIN D, CEGIELSKI J, SAYA M, CROSSLAND H, WILLIAMS JP, SMITH K, IDRIS I and ATHERTON PJ, 2020. Glucagon-like peptide 1 infusions overcome anabolic resistance to feeding in older human muscle Ageing Cell. e13202
CROSSLAND, HANNAH, PIASECKI, JESSICA, MCCORMICK, DANIEL, PHILLIPS, BETHAN E., WILKINSON, DANIEL J., SMITH, KENNETH, MCPHEE, JAMIE S., PIASECKI, MATHEW and ATHERTON, PHILIP J., 2020. Targeted genotype analyses of GWAS-derived lean body mass and handgrip strength-associated single-nucleotide polymorphisms in elite master athletes AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 319(2), R184-R194 BASS JJ, NAKHUDA A, DEANE CS, BROOK MS, WILKINSON DJ, PHILLIPS BE, PHILP A, TARUM J, KADI F, ANDERSEN D, GARCIA AM, SMITH K, GALLAGHER IJ, SZEWCZYK NJ, CLEASBY DE and ATHERTON PJ, 2020. Over-expression of the vitamin D receptor (VDR) induces skeletal muscle hypertrophy Molecular Metabolism. 42, 101059 WILKINSON DJ, RODRIGUEZ-BLANCO G, DUNN WB, PHILLIPS BE, WILLIAMS JP, GREENHAFF PL, SMITH K, GALLAGHER IJ and ATHERTON PJ, 2020. Untargeted metabolomics for uncovering biological markers of human skeletal muscle ageing Aging (Albany NY). 12(13), 12517-12533 CROSSLAND H, SMITH K, IDRIS I, PHILLIPS BE, ATHERTON PJ and WILKINSON DJ, 2020. Exploring mechanistic links between extracellular BCAA & muscle insulin resistance: an in vitro approach Am J Physiol Cell Physiol. 319(6), C1151-C1157 BASS JJ, KAZI AA, DEANE CS, NAKHUDA A, ASHCROFT SP, BROOK MS, WILKINSON DJ, PHILLIPS BE, PHILP A, TARUM J, KADI F, ANDERSEN D, GARCIA AM, SMITH K, GALLAGHER IJ, SZEWCZYK NJ, CLEASBY ME and ATHERTON PJ, 2020. The mechanisms of skeletal muscle atrophy in response to transient knockdown of the vitamin D receptor (VDR) in vivo J Physiol. 599(3), 063-070 DEANE CS, AMES RM, PHILLIPS BE, WEEDON MN, WILLIS CRG, BOEREBOOM C, ABDULLA H, BUKHARI SSI, LUND JN, WILLIAMS JP, WILKINSON DJ, SMITH K, GALLAGHER IJ, KADI F, SZEWCZYK NJ, ATHERTON PJ and ETHERIDGE T, 2019. The acute transcriptional response to resistance exercise: impact of age and contraction mode. Aging. 11(7), 2111-2126 DAVIES RW, BASS JJ, CARSON BP, NORTON C, KOZIOR M, AMIGO-BENAVENT M, WILKINSON DJ, BROOK MS, ATHERTON PJ, SMITH K and JAKEMAN PM, 2019. Differential Stimulation of Post-Exercise Myofibrillar Protein Synthesis in Humans Following Isonitrogenous, Isocaloric Pre-Exercise Feeding. Nutrients. 11(7), GHARAHDAGHI N, RUDRAPPA S, BROOK MS, IDRIS I, CROSSLAND H, HAMROCK C, ABDUL AZIZ MH, KADI F, TARUM J, GREENHAFF PL, CONSTANTIN-TEODOSIU D, CEGIELSKI J, PHILLIPS BE, WILKINSON DJ, SZEWCZYK NJ, SMITH K and ATHERTON PJ, 2019. Testosterone therapy induces molecular programming augmenting physiological adaptations to resistance exercise in older men J Cachexia Sarcopenia Muscle. 10(6), 1276-1294 ABDULLA H, BASS JJ, STOKES T, GORISSEN SHM, MCGLORY C, PHILLIPS BE, PHILLIPS SM, SMITH K, IDRIS I and ATHERTON PJ, 2019. The Effect of Oral Essential Amino Acids on Incretin Hormone Production in Youth and Ageing Endocrinol Diabetes Metab. 2(4), e00085 PUTHUCHEARY ZA, ASTIN R, MCPHAIL MJW, SAEED S, PASHA Y, BEAR DE, CONSTANTIN D, VELLOSO C, MANNING S, CALVERT L, SINGER M, BATTERHAM RL, GOMEZ-ROMERO M, HOLMES E, STEINER MC, ATHERTON PJ, GREENHAFF PL, EDWARDS LM, SMITH K, HARRIDGE SD, HART N and MONTGOMERY HE, 2018. Metabolic phenotype of skeletal muscle in early critical illness Thorax. pii: thoraxjnl-2017-211073 JACKMAN SR, BROOK MS, PULSFORD RM, COCKCROFT EJ, CAMPBELL MI, RANKIN D, ATHERTON PJ, SMITH K and BOWTELL JL, 2018. Tart cherry concentrate does not enhance muscle protein synthesis response to exercise and protein in healthy older men Exp Gerontol. 110, 202-208 GNIMASSOU O, FERNANDEZ-VERDEJO R, BROOK M, NASLAIN D, BALAN E, SAYDA M, CEGIELSKI J, NIELENS H, DECOTTIGNIES A, DEMOULIN JB, SMITH K, ATHERTON PJ, FRANCAUX M and DELDICQUE L, 2018. Environmental hypoxia favors myoblast differentiation and fast phenotype but blunts activation of protein synthesis after resistance exercise in human skeletal muscle FASEB J. fj201800049RR FRANCHI MV, RUOSS S, VALDIVIESO P, MITCHELL KW, SMITH K, ATHERTON PJ, NARICI MV and FLUCK M, 2018. Regional regulation of focal adhesion kinase after concentric and eccentric loading is related to remodelling of human skeletal muscle Acta Physiol (Oxf). 223(3), e13056 IMPEY SG, HAMMOND KM, NAUGHTON R, LANGAN-EVANS C, SHEPHERD SO, SHARPLES AP, CEGIELSKI J, SMITH K, JEROMSON S, HAMILTON DL, CLOSE GL and MORTON JP, 2018. Whey Protein Augments Leucinemia and Post-Exercise p70S6K1 Activity Compared to a Hydrolysed Collagen Blend When in Recovery From Training With Low Carbohydrate Availability Int J Sport Nutr Exerc Metab. 14, 1-26 BASS JJ, WILKINSON D, RANKIN D, PHILLIPS BE, SZEWCZYK NJ and SMITH K, 2017. An overview of technical considerations for Western blotting applications to physiological research. Scandinavian journal of medicine & science in sports. 27(1), 4-25 DEANE CS, WILKINSON DJ, PHILLIPS BE, SMITH K, ETHERIDGE T and ATHERTON PJ, 2017. "Nutraceuticals" in relation to human skeletal muscle and exercise. American journal of physiology. Endocrinology and metabolism. 312(4), E282-E299 BROOK, MATTHEW S., WILKINSON, DANIEL J., ATHERTON, PHILIP J. and SMITH, KEN, 2017. Recent developments in deuterium oxide tracer approaches to measure rates of substrate turnover: implications for protein, lipid, and nucleic acid research CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE. 20(5), 375-381 WILKINSON, DANIEL J., BROOK, MATTHEW S., SMITH, KENNETH and ATHERTON, PHILIP J., 2017. Stable isotope tracers and exercise physiology: past, present and future JOURNAL OF PHYSIOLOGY-LONDON. 595(9), 2873-2882 ATHERTON, PHILIP J., KUMAR, VINOD, SELBY, ANNA L., RANKIN, DEBBIE, HILDEBRANDT, WULF, PHILLIPS, BETH E., WILLIAMS, JOHN P., HISCOCK, NATALIE and SMITH, KENNETH, 2017. Enriching a protein drink with leucine augments muscle protein synthesis after resistance exercise in young and older men CLINICAL NUTRITION. 36(3), 888-895 BROOK MS, WILKINSON DJ, MITCHELL WK, LUND JL, PHILLIPS BE, SWECZYK NJ, KAINULAINEN H, LENSU S, KOCH LG, BRITTON SL, GREENHAFF PL, SMITH K and ATHERTON PJ, 2017. A novel D2O tracer method to quantify RNA turnover as a biomarker of de novo ribosomal biogenesis, in vitro, in animal models, and in human skeletal muscle. American journal of physiology. Endocrinology and metabolism. ajpendo.00157.2017 (In Press.)
IMPEY SG, HAMMOND KM, SHEPHERD SO, SHARPLES AP, STEWART C, LIMB M, SMITH K, PHILP A, JEROMSON S, HAMILTON DL, CLOSE GL and MORTON JP, 2016. Fuel for the work required: a practical approach to amalgamating train-low paradigms for endurance athletes. Physiological reports. 4(10), PHILLIPS BE, ATHERTON PJ, VARADHAN K, LIMB MC, WILLIAMS JP and SMITH K, 2016. Acute cocoa flavanol supplementation improves muscle macro- and microvascular but not anabolic responses to amino acids in older men. Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme. 41(5), 548-56 MITCHELL WK, WILKINSON DJ, PHILLIPS BE, LUND JN and SMITH K, 2016. Human Skeletal Muscle Protein Metabolism Responses to Amino Acid Nutrition Adv Nutr. 7(4), 828S-838S RUDRAPPA SS, WILKINSON D, GREENHAFF PL, SMITH K and IDRIS I, 2016. Human skeletal muscle disuse atrophy: effects on muscle protein synthesis, breakdown and insulin resistance—A Qualitative Review Frontiers in Physiology: Striated Muscle Physiology. 25(7), 361 BROOK MS, WILKINSON DJ, MITCHELL MK, LUND JN, PHILLIPS BE, SZEWCYZK NJ, GREENHAFF PL, SMITH K and ATHERTON PJ, 2016. Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans. JOURNAL OF PHYSIOLOGY-LONDON. 594(24), 7399–7417 WILKINSON DJ, BROOK MS, SMITH K and ATHERTON PJ, 2016. Stable isotope tracers and exercise physiology: Past, present and future. The Journal of physiology. (In Press.)
MITCHELL WK, PHILLIPS BE, WILKINSON DJ, WILLIAMS JP, RANKIN D, LUND JN, SMITH K and ATHERTON PJ, 2016. Supplementing essential amino acids with the nitric oxide precursor, l-arginine, enhances skeletal muscle perfusion without impacting anabolism in older men. Clinical nutrition (Edinburgh, Scotland). (In Press.)
ANDERSON AJ, ANDREW R, HOMER NZ, JONES GC, SMITH K, LIVINGSTONE DE, WALKER BR and STIMSON RH, 2016. Metformin Increases Cortisol Regeneration by 11βHSD1 in Obese Men With and Without Type 2 Diabetes Mellitus. The Journal of clinical endocrinology and metabolism. 101(10), 3787-3793 BROOK, MATTHEW S., WILKINSON, DANIEL J., SMITH, KENNETH and ATHERTON, PHILIP J., 2016. The metabolic and temporal basis of muscle hypertrophy in response to resistance exercise EUROPEAN JOURNAL OF SPORT SCIENCE. 16(6), 633-644 PHILLIPS, BETHAN E., ATHERTON, PHILIP J., VARADHAN, KRISHNA, LIMB, MARIE C., WILLIAMS, JOHN P. and SMITH, KENNETH, 2016. Acute cocoa flavanol supplementation improves muscle macro- and microvascular but not anabolic responses to amino acids in older men APPLIED PHYSIOLOGY NUTRITION AND METABOLISM. 41(5), 548-556 BROOK, M. S., WILKINSON, D. J., PHILLIPS, B. E., PEREZ-SCHINDLER, J., PHILP, A., SMITH, K. and ATHERTON, P. J., 2016. Skeletal muscle homeostasis and plasticity in youth and ageing: impact of nutrition and exercise ACTA PHYSIOLOGICA. 216(1), 15-41 BELTRAN VALLS MR, WILKINSON DJ, NARICI MV, SMITH K, PHILLIPS BE, CAPOROSSI D and ATHERTON PJ, 2015. Protein Carbonylation and Heat Shock Proteins in Human Skeletal Muscle: Relationships to Age and Sarcopenia. The journals of gerontology. Series A, Biological sciences and medical sciences. 70(2), 174-81 MALLINSON JE, MARIMUTHU K, MURTON A, SELBY A, SMITH K, CONSTANTIN-TEODOSIU D, RENNIE MJ and GREENHAFF PL, 2015. Statin myalgia is not associated with reduced muscle strength, mass or protein turnover in older male volunteers, but is allied with a slowing of time to peak power output, insulin resistance and differential muscle mRNA expression. The Journal of physiology. 593(5), 1239-1257 MITCHELL WK, PHILLIPS BE, WILLIAMS JP, RANKIN D, LUND JN, WILKINSON DJ, SMITH K and ATHERTON PJ, 2015. The impact of delivery profile of essential amino acids upon skeletal muscle protein synthesis in older men: clinical efficacy of pulse vs. bolus supply. American journal of physiology. Endocrinology and metabolism. ajpendo.00112.2015 (In Press.)
MURTON, ANDREW J., MARIMUTHU, KANAGARAJ, MALLINSON, JOANNE E., SELBY, ANNA L., SMITH, KENNETH, RENNIE, MICHAEL J. and GREENHAFF, PAUL L., 2015. Obesity Appears to Be Associated With Altered Muscle Protein Synthetic and Breakdown Responses to Increased Nutrient Delivery in Older Men, but Not Reduced Muscle Mass or Contractile Function DIABETES. 64(9), 3160-3171 FRANCHI MV, WILKINSON DJ, QUINLAN JI, MITCHELL WK, LUND JN, WILLIAMS JP, REEVES ND, SMITH K, ATHERTON PJ and NARICI MV, 2015. Early structural remodeling and deuterium oxide-derived protein metabolic responses to eccentric and concentric loading in human skeletal muscle. Physiological reports. 3(11), BROOK MS, WILKINSON DJ, SMITH K and ATHERTON PJ, 2015. The metabolic and temporal basis of muscle hypertrophy in response to resistance exercise. European journal of sport science. 16(6), 633-44 BROOK MS, WILKINSON DJ, PHILLIPS BE, PEREZ-SCHINDLER J, PHILP A, SMITH K and ATHERTON PJ, 2015. Skeletal muscle homeostasis and plasticity in youth and ageing: impact of nutrition and exercise. Acta physiologica (Oxford, England). 216(1), 15-41 WILKINSON DJ, ATHERTON PJ, PHILLIPS BE, GREENHAFF PL and SMITH K, 2015. Application of deuterium oxide (D2O) to metabolic research: just D2O it? Depends just how you D2O it! American journal of physiology. Endocrinology and metabolism. 308(9), E847 PHILLIPS BE, ATHERTON PJ, VARADHAN K, LIMB MC, WILKINSON DJ, SJØBERG KA, SMITH K and WILLIAMS JP, 2015. The effects of resistance exercise training on macro- and micro-circulatory responses to feeding and skeletal muscle protein anabolism in older men. The Journal of physiology. 593(12), 2721-34 BUKHARI SS, PHILLIPS BE, WILKINSON DJ, LIMB MC, RANKIN D, MITCHELL WK, KOBAYASHI H, GREENHAFF PL, SMITH K and ATHERTON PJ, 2015. Intake of low-dose leucine-rich essential amino acids stimulates muscle anabolism equivalently to bolus whey protein in older women at rest and after exercise. American journal of physiology. Endocrinology and metabolism. 308(12), E1056-65 WILKINSON DJ, FRANCHI MV, BROOK MS, NARICI MV, WILLIAMS JP, MITCHELL WK, SZEWCZYK NJ, GREENHAFF PL, ATHERTON PJ and SMITH K, 2014. A validation of the application of D2O stable isotope tracer techniques for monitoring day-to-day changes in muscle protein sub-fraction synthesis in humans. American journal of physiology. Endocrinology and metabolism. 306(5), E571-9 ABDULLA H, PHILLIPS B, SMITH K, WILKINSON D, ATHERTON P and IDRIS I, 2014. Physiological Mechanisms of Action of Incretin and Insulin in Regulating Skeletal Muscle Metabolism. Current diabetes reviews. (In Press.)
PHILLIPS BE, ATHERTON PJ, VARADHAN K, WILKINSON DJ, LIMB M, SELBY AL, RENNIE MJ, SMITH K and WILLIAMS JP, 2014. Pharmacological enhancement of leg and muscle microvascular blood flow does not augment anabolic responses in skeletal muscle of young men under fed conditions. American journal of physiology. Endocrinology and metabolism. 306(2), E168-76 IMPEY SG, SMITH D, ROBINSON AL, OWENS DJ, BARTLETT JD, SMITH K, LIMB M, TANG J, FRASER WD, CLOSE GL and MORTON JP, 2014. Leucine-enriched protein feeding does not impair exercise-induced free fatty acid availability and lipid oxidation: beneficial implications for training in carbohydrate-restricted states. Amino acids. 47(2), 407-16 PHILLIPS BE, SMITH K, LIPTROT S, ATHERTON PJ, VARADHAN K, RENNIE MJ, LARVIN M, LUND JN and WILLIAMS JP, 2013. Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study J Cachexia Sarcopenia Muscle. 4(1), 71-77 PHILLIPS BE, WILLIAMS JP, GUSTAFFSON T, BOUCHARD C, RANKINEN T, KNUDSEN S, SMITH K and TIMMONS JA, 2013. Molecular Networks of Human Muscle Adaptation to Exercise and Age PloS Genetics. 9(3), CROSSLAND H, KAZI AA, LANG CH, TIMMONS JA, PIERRE P, WILKINSON DJ, SMITH K, SZEWCZYK NJ and ATHERTON PJ, 2013. Focal adhesion kinase is required for IGF-I-mediated growth of skeletal muscle cells via a TSC2/mTOR/S6K1-associated pathway. American journal of physiology. Endocrinology and metabolism. 305(2), E183-93 BREEN L, STOKES KA, CHURCHWARD-VENNE TA, MOORE DR, BAKER SK, SMITH K, ATHERTON PJ and PHILLIPS SM, 2013. Two weeks of reduced activity decreases leg lean mass and induces "anabolic resistance" of myofibrillar protein synthesis in healthy elderly. The Journal of clinical endocrinology and metabolism. 98(6), 2604-12 PUTHUCHEARY, Z.A., RAWAL, J., MCPHAIL, M., CONNOLLY, B., RATNAYAKE, G., CHAN, P., HOPKINSON, N.S., PADHKE, R., DEW, T., SIDHU, P.S., VELLOSO, C., SEYMOUR, J., AGLEY, C.C., SELBY, A., LIMB, M., EDWARDS, L.M., SMITH, K., ROWLERSON, A., RENNIE, M.J., MOXHAM, J., HARRIDGE, S.D.R., HART, N. and MONTGOMERY, H.E., 2013. Acute skeletal muscle wasting in critical illness JAMA: the Journal of the American Medical Association. 310(15), 1591-1600 PHILLIPS BE, SMITH K, LIPTROT S, ATHERTON PJ, VARADHAN K, RENNIE MJ, LARVIN M, LUND JN and WILLIAMS JP, 2013. Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study. Journal of cachexia, sarcopenia and muscle. 4(1), 71-7 WILKINSON DJ, HOSSAIN T, HILL DS, PHILLIPS BE, CROSSLAND H, WILLIAMS J, LOUGHNA P, CHURCHWARD-VENNE TA, BREEN L, PHILLIPS SM, ETHERIDGE T, RATHMACHER JA, SMITH K, SZEWCZYK NJ and ATHERTON PJ, 2013. Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism. The Journal of physiology. 591(Pt 11), 2911-23 PHILLIPS BE, WILLIAMS JP, GUSTAFSSON T, BOUCHARD C, RANKINEN T, KNUDSEN S, SMITH K, TIMMONS JA and ATHERTON PJ, 2013. Molecular networks of human muscle adaptation to exercise and age. PLoS genetics. 9(3), e1003389 PHILLIPS B., WILLIAMS J., ATHERTON P., SMITH K., HILDEBRANDT W., RANKIN D., GREENHAFF P., MACDONALD I. and RENNIE M.J., 2012. Resistance exercise training improves age-related declines in leg vascular conductance and rejuvenates acute leg blood flow responses to feeding and exercise Journal of Applied Physiology. 112(3), 347-353 ATHERTON PJ and SMITH K, 2012. Role of Protein Turnover in Adaptation J Physiol. Epub ahead of print(PMID 22289911), (In Press.)
WILLIAMS, J.P., PHILLIPS, B.E., SMITH, K., ATHERTON, P.J., RANKIN, D., SELBY, A.L., LIPTROT, S., LUND, J., LARVIN, M. and RENNIE, M.J., 2012. Effect of tumor burden and subsequent surgical resection on skeletal muscle mass and protein turnover in colorectal cancer patients American Journal of Clinical Nutrition. 96(5), 1064-1070 KUMAR, V., ATHERTON, P.J., SELBY, A., RANKIN, D., WILLIAMS, J., SMITH, K., HISCOCK, N. and RENNIE, M.J., 2012. Muscle protein synthetic responses to exercise: effects of age, volume, and intensity Journals of Gerontology: A, Biological Sciences. 67(11), 1170–1177 MILLER BF, HAMILTON KL, CUTHBERTSON DJ, SMITH K, WILLIAMS J, MITTENDORFER B, GREENHAFF P and ATHERTON P, 2012. Commentaries on viewpoint: the curious case of anabolic resistance: old wives' tales or new fables? Journal of Applied Physiology. 112(7), 1236 ETHERIDGE, T., ATHERTON, P.J., WILKINSON, D., SELBY, A., RANKIN, D., WEBBORN, N., SMITH, K. and WATT, P.W., 2011. Effects of hypoxia on muscle protein synthesis (MPS) and anabolic signalling at rest and in response to acute resistance exercise American Journal of Physiology. Endocrinology and Metabolism. 301(4), E697-E702 ATHERTON, PHILIP J, SMITH, KEN, ETHERIDGE, TIMOTHY, RANKIN, DEBBIE and RENNIE, MICHAEL J, 2010. Distinct anabolic signalling responses to amino acids in C2C12 skeletal muscle cells. Amino acids. 38(5), 1533-9 RENNIE, M J, SELBY, A, ATHERTON, P, SMITH, K, KUMAR, V, GLOVER, E L and PHILIPS, S M, 2010. Facts, noise and wishful thinking: muscle protein turnover in aging and human disuse atrophy. Scandinavian journal of medicine & science in sports. 20(1), 5-9 ATHERTON, P.J., ETHERIDGE, T., WATT, P.W., WILKINSON, D., SELBY, A., RANKIN, D., SMITH, K. and RENNIE, M.J., 2010. Muscle full effect after oral protein: time-dependent concordance and discordance between human muscle protein synthesis and mTORC1 signaling American Journal of Clinical Nutrition. 92(5), 1080-1088 WATT, KEVIN I, JASPERS, RICHARD T, ATHERTON, PHILLIP, SMITH, KEN, RENNIE, MICHAEL J, RATKEVICIUS, AIVARAS and WACKERHAGE, HENNING, 2010. SB431542 treatment promotes the hypertrophy of skeletal muscle fibers but decreases specific force. Muscle & nerve. 41(5), 624-9 DOESSING, S., HEINEMEIER, K.M., HOLM, L., MACKEY, A.L., SCHJERLING, P., RENNIE, M., SMITH, K., REITELSEDER, S., KAPPELGAARD, A.-M., RASMUSSEN, M.H., FLYVBJERG, A. and KJAER, M., 2010. Growth hormone stimulates the collagen synthesis in human tendon and skeletal muscle without affecting myofibrillar protein synthesis Journal of Physiology. 588(2), 341-351 WILKES, E.A., SELBY, A.L., ATHERTON, P.J., PATEL, R., RANKIN, D., SMITH, K. and RENNIE, M.J., 2009. Blunting of insulin inhibition of proteolysis in legs of older subjects may contribute to age-related sarcopenia The American Journal of Clinical Nutrition. 90(5), 1343-1350 ATHERTON, P.J., SZEWCZYK, N.J., SELBY, A., RANKIN, D., HILLIER, K., SMITH, K., RENNIE, M.J. and LOUGHNA, P.T., 2009. Cyclic stretch reduces myofibrillar protein synthesis despite increases in FAK and anabolic signalling in L6 cells. The Journal of Physiology. 587(14), 3719-3727 KUMAR, V., SELBY, A., RANKIN, D., PATEL, R., ATHERTON, P., HILDEBRANDT, W., WILLIAMS, J., SMITH, K., SEYNNES, O., HISCOCK, N. and RENNIE, M.J., 2009. Age-related differences in the dose-response relationship of muscle protein synthesis to resistance exercise in young and old men Journal of Physiology. 587(1), 211-217 KUMAR, VINOD, ATHERTON, PHILIP, SMITH, KENNETH and RENNIE, MICHAEL J, 2009. Human muscle protein synthesis and breakdown during and after exercise. Journal of applied physiology (Bethesda, Md. : 1985). 106(6), 2026-39 BABRAJ, JOHN ANDREE, MUSTARD, KRISTY, SUTHERLAND, CALUM, TOWLER, MHARI C, CHEN, SHAUI, SMITH, KENNETH, GREEN, KEVIN, LEESE, GRAHAM, HARDIE, DAVID GRAHAME, RENNIE, MICHAEL J and CUTHBERTSON, DANIEL JAMES, 2009. Blunting of AICAR-induced human skeletal muscle glucose uptake in type 2 diabetes is dependent on age rather than diabetic status. American journal of physiology. Endocrinology and metabolism. 296(5), E1042-8 GREENHAFF, P.L., KARAGOUNIS, L.G., PIERCE, N,, SIMPSON, E.J., HAZELL, M., LAYFIELD, R., WACKERHAGE, H., SMITH, K., ATHERTON, P., SELBY, A. and RENNIE, M.J., 2008. Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle American Journal of Physiology: Endocrinology and Metabolism. 295(3), E595-E604 GLOVER, E.I., PHILLIPS, S.M., OATES, B.R., TANG, J.E., TARNOPOLSKY, M.A., SELBY, A., SMITH, K. and RENNIE, M.J., 2008. Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion Journal of Physiology. 586(24), 6049-6061 RENNIE, MICHAEL J, PHILLIPS, STUART and SMITH, KENNETH, 2008. Reliability of results and interpretation of measures of 3-methylhistidine in muscle interstitium as marker of muscle proteolysis. Journal of applied physiology (Bethesda, Md. : 1985). 105(4), 1380-1; author reply 1382-3 DE BOER, M., SELBY, A., ATHERTON, P., SMITH, K., SEYNNES, O.R., MAGANARIS, C.N., MAFFULLI, N., MOVIN, T., NARICI, M.V. and RENNIE, M.J., 2007. The temporal responses of protein synthesis, gene expression and cell signalling in human quadriceps muscle and patellar tendon to disuse. Journal of Physiology. 585(1), 241-251 PETERSEN, A.M.W., MAGKOS, F., ATHERTON, P., SELBY, A., SMITH, K., RENNIE, M.J., PEDERSEN, B.K. and MITTENDORFER, B, 2007. Smoking impairs muscle protein synthesis and increases the expression of myostatin and MAFbx in muscle. American Journal of Physiology: Endocrinology and Metabolism. 2007, 1-23 RENNIE,, ATHERTON,, SELBY,, SMITH,, NARICI,, DE BOER,, PHILLIPS, and GLOVER,, 2007. Letter to the Editor on the Journal Club article by Barker and Traber. Journal of Physiology. SMITH, KEN and RENNIE, MICHAEL J, 2007. New approaches and recent results concerning human-tissue collagen synthesis. Current Opinion in Clinical Nutrition and Metabolic Care. 10(5), 582-90 MILLER, BENJAMIN F, HANSEN, METTE, OLESEN, JENS L, SCHWARZ, PETER, BABRAJ, JOHN A, SMITH, KENNETH, RENNIE, MICHAEL J and KJAER, MICHAEL, 2007. Tendon collagen synthesis at rest and after exercise in women. Journal of Applied Physiology. 102(2), 541-6 RENNIE MJ, BOHÉ J, SMITH K, WACKERHAGE H and GREENHAFF P, 2006. Branched-chain amino acids as fuels and anabolic signals in human muscle. The Journal of nutrition. 136(1 Suppl), 264S-8S
CUTHBERTSON, D.J., BABRAJ, J., SMITH, K., WILKES, E., FEDELE, M.J., ESSER, K. and RENNIE, M, 2006. Anabolic signaling and protein synthesis in human skeletal muscle after dynamic shortening or lengthening exercise. American Journal of Physiology: Endocrinology and Metabolism. 290(4), E731-E738 MILLER, BENJAMIN F, HANSEN, METTE, OLESEN, JENS L, FLYVBJERG, ALLAN, SCHWARZ, PETER, BABRAJ, JOHN A, SMITH, KENNETH, RENNIE, MICHAEL J and KJAER, MICHAEL, 2006. No effect of menstrual cycle on myofibrillar and connective tissue protein synthesis in contracting skeletal muscle. American Journal of Physiology: Endocrinology and Metabolism. 290(1), E163-E168 CHEE C, SHANNON CE, BURNS A, SELBY AL, WILKINSON D, SMITH K, GREENHAFF PL and STEPHENS FB, 2006. The relative contribution of intramyocellular lipid to whole body fat oxidation is reduced with age, but subsarcolemmal lipid accumulation and insulin resistance are only associated with overweight individuals Diabetes. pii: db151383,
ATHERTON, P J, BABRAJ, J, SMITH, K, SINGH, J, RENNIE, M J and WACKERHAGE, H, 2005. Selective activation of AMPK-PGC-1alpha or PKB-TSC2-mTOR signaling can explain specific adaptive responses to endurance or resistance training-like electrical muscle stimulation. FASEB Journal. 19(7), 786-788 CUTHBERTSON, D., SMITH, K.H, BABRAJ, J., LEESE, G., WADDELL, T., ATHERTON, P., WACKERHAGE, H., TAYLOR, P.M. and RENNIE, M.J, 2005. Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle. FASEB Journal. 19(3), 422-424 BABRAJ, J.A., SMITH, K., CUTHBERTSON, D.J., RICKHUSS, P., DORLING, J.S. and RENNIE, M.J, 2005. Human bone collagen synthesis is a rapid, nutritionally modulated process. Journal of Bone and Mineral Research. 20(6), 930-7 MITTENDORFER, B., ANDERSEN, J.L., PLOMGAARD, P., SALTIN, B., BABRAJ, J.A., SMITH, K. and RENNIE, M.J, 2005. Protein synthesis rates in human muscles: neither anatomical location nor fibre-type composition are major determinants. Journal of Physiology. 563(1), 203-211 BABRAJ, J.A, CUTHBERTSON, D.J.R., SMITH, K., LANGBERG, H., MILLER, B., KROGSGAARD, M.R., KJAER, M. and RENNIE, M.J, 2005. Collagen synthesis in human musculoskeletal tissues and skin. American Journal of Physiology: Endocrinology and Metabolism. 289(5), E864-E869 MOORE, DANIEL R, PHILLIPS, STUART M, BABRAJ, JOHN A, SMITH, KENNETH and RENNIE, MICHAEL J, 2005. Myofibrillar and collagen protein synthesis in human skeletal muscle in young men after maximal shortening and lengthening contractions. American Journal of Physiology: Endocrinology and Metabolism. 288(6), E1153-9 LOUIS, M., POORTMANS, J. R., FRANCAUX, M., BERRE, J., BOISSEAU, N., BRASSINE, E., CUTHBERTSON, D. J. R., SMITH, K., BABRAJ, J. A. and WADDELL, T., 2003. No effect of creatine supplementation on human myofibrillar and sarcoplasmic protein synthesis after resistance exercise American Journal of Physiology. VOL 285(ISSU 5), E1089
LOUIS, MAGALI, POORTMANS, JACQUES R, FRANCAUX, MARC, HULTMAN, ERIC, BERRE, JACQUES, BOISSEAU, NATHALIE, YOUNG, VERNON R, SMITH, KENNETH, MEIER-AUGENSTEIN, WOLFRAM, BABRAJ, JOHN A, WADDELL, TOM and RENNIE, MICHAEL J, 2003. Creatine supplementation has no effect on human muscle protein turnover at rest in the postabsorptive or fed states. American Journal of Physiology: Endocrinology and Metabolism. 284(4), E764-70
ANDREW, R., SMITH, K., JONES, G.C. and WALKER, B.R, 2002. Distinguishing the activities of 11beta-hydroxysteroid dehydrogenases in vivo using isotopically labeled cortisol. Journal of Clinical Endocrinology and Metabolism. 87(1), 277-285 BABRAJ, J, CUTHBERTSON, D J, RICKHUSS, P, MEIER-AUGENSTEIN, W, SMITH, K, BOHé, J, WOLFE, R R, GIBSON, J N A, ADAMS, C and RENNIE, M J, 2002. Sequential extracts of human bone show differing collagen synthetic rates. Biochemical Society Transactions. 30(2), 61-5 LIVINGSTONE, D E, JONES, G C, SMITH, K, JAMIESON, P M, ANDREW, R, KENYON, C J and WALKER, B R, 2000. Understanding the role of glucocorticoids in obesity: tissue-specific alterations of corticosterone metabolism in obese Zucker rats. Endocrinology. 141(2), 560-3