Contact

• workRoom 4106 The Medical School
  Royal Derby Hospital
  Uttoxeter Road
  Derby
  DE22 3DT
  UK
• work01332 724 668
• Timothy.England@nottingham.ac.uk

Biography

Professor in Stroke Medicine & Honorary Consultant Physician (Royal Derby Hospital)

My undergraduate medical years were at the University of Leicester (1996 - 2001) and I trained in Health Care for the Elderly and General Internal Medicine (Nottingham University Hospitals, CCT 2011) during which time I obtained a PhD in Stroke Medicine at the University of Nottingham.

Expertise Summary

My research interests embrace the hyperacute phase of stroke, assessing potential treatments such as remote ischaemic pre- per and post-conditioning; the role of cannabinoids in the vasculature and blood brain barrier; post-stroke dysphagia recovery; and blood pressure and stroke. I am the Chief Investigator for the RECAST trials and support various clinical studies through the Nottingham Stroke Trials Unit, currently including TICH-3 and PhEAST. I'm additionally interested in the impact of frailty on treatments used in stroke, running an East-Midlands based frailty cohort study FINE-ST. I am the NIHR CRN East Midlands Lead for Stroke.

Teaching Summary

I provide regular teaching and training at both undergraduate and post-graduate levels. Specific roles include lectures and seminars to Undergraduate and Graduate Entry Medical (GEM) Students; BSc… read more

Research Summary

I am a clinical trialist in Stroke and the Chief Investigator of the RECAST trials (Remote Ischaemic Conditioning After Stroke) . Other active interests include the effects of cannabinoids on… read more

Recent Publications

• DHILLON, PERMESH SINGH, BUTT, WALEED, PODLASEK, ANNA, MCCONACHIE, NORMAN, LENTHALL, ROBERT, NAIR, SUJIT, MALIK, LUQMAN, BOOTH, THOMAS C., BHOGAL, PERVINDER, MAKALANDA, HEGODA LEVANSRI DILRUKSHAN, SPOONER, OLIVER, MORTIMER, ALEX, LAMIN, SALEH, CHAVDA, SWARUPSINH, CHEW, HAN SENG, NADER, KURDOW, AL-ALI, SAMER, BUTLER, BENJAMIN, RAJAPAKSE, DILINA, APPLETON, JASON P., KRISHNAN, KAILASH, SPRIGG, NIKOLA, SMITH, AUBREY, LOBOTESIS, KYRIAKOS, WHITE, PHIL, JAMES, MARTIN A., BATH, PHILIP M., DINEEN, ROBERT A. and ENGLAND, TIMOTHY J., 2022. Perfusion Imaging for Endovascular Thrombectomy in Acute Ischemic Stroke Is Associated With Improved Functional Outcomes in the Early and Late Time Windows STROKE. 53(9), 2770-2778
• DHILLON, PERMESH SINGH, BUTT, WALEED, PODLASEK, ANNA, MCCONACHIE, NORMAN, LENTHALL, ROBERT, NAIR, SUJIT, MALIK, LUQMAN, HEWSON, DAVID W., BHOGAL, PERVINDER, MAKALANDA, HEGODA LEVANSRI DILRUKSHAN, JAMES, MARTIN A., DINEEN, ROBERT A. and ENGLAND, TIMOTHY J., 2022. Association between anesthesia modality and clinical outcomes following endovascular stroke treatment in the extended time window JOURNAL OF NEUROINTERVENTIONAL SURGERY.
• PSZCZOLKOWSKI, STEFAN, SPRIGG, NIKOLA, WOODHOUSE, LISA J., GALLAGHER, REBECCA, SWIENTON, DAVID, LAW, ZHE KANG, CASADO, ANA M., ROBERTS, IAN, WERRING, DAVID J., SALMAN, RUSTAM AL-SHAHI, ENGLAND, TIMOTHY J., MORGAN, PAUL S., BATH, PHILIP M. and DINEEN, ROBERT A., 2022. Effect of Tranexamic Acid Administration on Remote Cerebral Ischemic Lesions in Acute Spontaneous Intracerebral Hemorrhage A Substudy of a Randomized Clinical Trial JAMA NEUROLOGY. 79(5), 468-477
• DHILLON, PERMESH SINGH, BUTT, WALEED, PODLASEK, ANNA, MCCONACHIE, NORMAN, LENTHALL, ROBERT, NAIR, SUJIT, MALIK, LUQMAN, BHOGAL, PERVINDER, MAKALANDA, HEGODA LEVANSRI DILRUKSHAN, SPOONER, OLIVER, KRISHNAN, KAILASH, SPRIGG, NIKOLA, MORTIMER, ALEX, BOOTH, THOMAS CALVERT, LOBOTESIS, KYRIAKOS, WHITE, PHILIP, JAMES, MARTIN A., BATH, PHILIP, DINEEN, ROBERT A. and ENGLAND, TIMOTHY J., 2022. Association between time to treatment and clinical outcomes in endovascular thrombectomy beyond 6 hours without advanced imaging selection JOURNAL OF NEUROINTERVENTIONAL SURGERY.

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I provide regular teaching and training at both undergraduate and post-graduate levels. Specific roles include lectures and seminars to Undergraduate and Graduate Entry Medical (GEM) Students; BSc Cardiovascular Module seminars, exam question generation and marking; Clinical Phase (CP) 3 and MAST student supervision; facilitating Problem Based Learning (Cardiovascular Module); regular bedside teaching CP1 and CP3 students; examining end of year CP1 and CP3 students; personal tutor to GEM students

Current Research

I am a clinical trialist in Stroke and the Chief Investigator of the RECAST trials (Remote Ischaemic Conditioning After Stroke) . Other active interests include the effects of cannabinoids on haemodynamics, treatment for post-stroke dysphagia and meta-analysis (pre-clinical and clinical).

I sit on the Trial Steering Committees (TSC) for LACI-2 (LACunar Intervention Trial-2), TICH-3 (Tranexamic acid in Intracerebral Haemorrhagic), and PhEAST (Pharyngeal Electrical stimulation for Acute Stroke dysphagia Trial). Previous trial steering committees include TICH-2, RIGHT-2 (Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2) and BEADS (BEhavioural Activation therapy for Depression after Stroke).

I am the East Midlands NIHR CRN lead for Stroke. I am an expert reviewer for the NIHR, NICE and contribute to the National Clinical Guideline for Stroke in the UK and Ireland.

• PSZCZOLKOWSKI S, SPRIGG N, WOODHOUSE LJ, GALLAGHER R, SWIENTON D, LAW ZK, CASADO AM, ROBERTS I, WERRING DJ, AL-SHAHI SALMAN R, ENGLAND TJ, MORGAN PS, BATH PM and DINEEN RA, 2022. Remote Cerebral Ischaemic Lesions After Tranexamic Acid For Acute Spontaneous Intracerebral Haemorrhage JAMA Neurol. 79(5), 468-477
• PODLASEK A, DHILLON PS, BUTT W, GRUNWALD IQ and ENGLAND TJ, 2022. To bridge or not to bridge: summary of the new evidence in endovascular stroke treatment Stroke Vasc Neurol. 7(3), 179-181
• DHILLON PS, BUTT W, PODLASEK A, BARRETT E, MCCONACHIE N, LENTHALL R, NAIR S, MALIK L, JAMES MA, DINEEN RA and ENGLAND TJ, 2022. Endovascular Thrombectomy Beyond 24 Hours From Ischaemic Stroke Onset: A Propensity Score-Matched Cohort Study J Neurointerv Surg. neurintsurg-2021-018591
• DHILLON PS, BUTT W, JOVIN TG, PODLASEK A, MCCONACHIE N, LENTHALL R, NAIR S, MALIK L, KRISHNAN K, CHIAVACCI I, MEHEDI F, HONG T, SELVA H, DINEEN RA and ENGLAND TJ, 2022. Endovascular Thrombectomy Vs Best Medical Therapy For Late Presentation Acute Ischaemic Stroke With Proximal Large Vessel Occlusion Selected Based On Non-Contrast CT: A Retrospective Analysis Of Two Prospectively Defined Cohorts Stroke: Vascular and Interventional Neurology. e000686
• BATH PM, SKINNER CJC, BATH CS, WOODHOUSE LJ, KOROVESI AAK, LONG J, HARVARD D, COLEMAN CM, ENGLAND TJ, LEYLAND V, LIM WS, MONTGOMERY AA, ROYAL S, AVERY A, WEBB AJ, GORDON AL and BEET INVESTIGATORS, 2022. Supplementation For Preventing And Reducing The Severity Of Winter Infections, Including COVID-19, In Care Homes (BEET-Winter)-a Randomised Placebo-controlled Feasibility Trial Eur Geriatr Med. 13(6), 1343-1355
• PURROY F, BERETTA S, ENGLAND TJ, HESS DC, PICO F and SHUAIB A, 2022. Remote Ischemic Conditioning (Pre, Per, and Post) as an Emerging Strategy of Neuroprotection in Ischemic Stroke Front Neurol. 13, 932891
• BELL RM, BASALAY M, BOTKER HE, KALKHORAN SB, CARR RD, CUNNINGHAM J, DAVIDSON SM, ENGLAND TJ, GIESZ S, GHOSH AK, GOLFOROUSH P, GOURINE AV, HAUSENLOY DJ, HEUSCH G, IBANEZ, KLEINBONGARD P, LECOUR S, LUKHNA K, NTSEKHE M, OVIZE M, SALAMA AD, VILAHUR G, WALKER JM and YELLON DM, 2022. Remote ischaemic conditioning: defining critical criteria for success-report from the 11th Hatter Cardiovascular Workshop Basic Res Cardiol. 117(1), 39
• DHILLON, PERMESH SINGH, BUTT, WALEED, PODLASEK, ANNA, MCCONACHIE, NORMAN, LENTHALL, ROBERT, NAIR, SUJIT, MALIK, LUQMAN, BHOGAL, PERVINDER, MAKALANDA, HEGODA LEVANSRI DILRUKSHAN, SPOONER, OLIVER, KRISHNAN, KAILASH, SPRIGG, NIKOLA, MORTIMER, ALEX, BOOTH, THOMAS CALVERT, LOBOTESIS, KYRIAKOS, WHITE, PHILIP, JAMES, MARTIN A., BATH, PHILIP, DINEEN, ROBERT A. and ENGLAND, TIMOTHY J., 2022. Association between time to treatment and clinical outcomes in endovascular thrombectomy beyond 6 hours without advanced imaging selection JOURNAL OF NEUROINTERVENTIONAL SURGERY.
• PSZCZOLKOWSKI, STEFAN, SPRIGG, NIKOLA, WOODHOUSE, LISA J., GALLAGHER, REBECCA, SWIENTON, DAVID, LAW, ZHE KANG, CASADO, ANA M., ROBERTS, IAN, WERRING, DAVID J., SALMAN, RUSTAM AL-SHAHI, ENGLAND, TIMOTHY J., MORGAN, PAUL S., BATH, PHILIP M. and DINEEN, ROBERT A., 2022. Effect of Tranexamic Acid Administration on Remote Cerebral Ischemic Lesions in Acute Spontaneous Intracerebral Hemorrhage A Substudy of a Randomized Clinical Trial JAMA NEUROLOGY. 79(5), 468-477
• DHILLON, PERMESH SINGH, BUTT, WALEED, PODLASEK, ANNA, MCCONACHIE, NORMAN, LENTHALL, ROBERT, NAIR, SUJIT, MALIK, LUQMAN, HEWSON, DAVID W., BHOGAL, PERVINDER, MAKALANDA, HEGODA LEVANSRI DILRUKSHAN, JAMES, MARTIN A., DINEEN, ROBERT A. and ENGLAND, TIMOTHY J., 2022. Association between anesthesia modality and clinical outcomes following endovascular stroke treatment in the extended time window JOURNAL OF NEUROINTERVENTIONAL SURGERY.
• DHILLON, PERMESH SINGH, BUTT, WALEED, PODLASEK, ANNA, MCCONACHIE, NORMAN, LENTHALL, ROBERT, NAIR, SUJIT, MALIK, LUQMAN, BOOTH, THOMAS C., BHOGAL, PERVINDER, MAKALANDA, HEGODA LEVANSRI DILRUKSHAN, SPOONER, OLIVER, MORTIMER, ALEX, LAMIN, SALEH, CHAVDA, SWARUPSINH, CHEW, HAN SENG, NADER, KURDOW, AL-ALI, SAMER, BUTLER, BENJAMIN, RAJAPAKSE, DILINA, APPLETON, JASON P., KRISHNAN, KAILASH, SPRIGG, NIKOLA, SMITH, AUBREY, LOBOTESIS, KYRIAKOS, WHITE, PHIL, JAMES, MARTIN A., BATH, PHILIP M., DINEEN, ROBERT A. and ENGLAND, TIMOTHY J., 2022. Perfusion Imaging for Endovascular Thrombectomy in Acute Ischemic Stroke Is Associated With Improved Functional Outcomes in the Early and Late Time Windows STROKE. 53(9), 2770-2778
• MAGUIRE RF, WILKINSON DJ, ENGLAND TJ and O'SULLIVAN SE, 2021. The Pharmacological Effects of Plant-Derived versus Synthetic Cannabidiol in Human Cell Lines Med Cannabis Cannabinoids. 4, 86-96
• LAW ZK, ENGLAND TJ, MISTRI AK, WOODHOUSE L, CALA L, ET AL and TICH-2 INVESTIGATORS, 2020. Incidence and predictors of early and late seizures in intracerebral haemorrhage European Stroke Journal. 0(0), 1-7
• BENFIELD JK, EVERTON LF, BATH PM and ENGLAND TJ, 2020. Accuracy and clinical utility of Nurse Dysphagia Assessments: a systematic review 29(9), 1527-1538
• SULTAN S, O'SULLIVAN S and ENGLAND TJ, 2020. Effects of acute and seven day Cannabidiol treatment on haemodynamics in Healthy Men Br J Clin Pharmacol. 86(6), 1125-1138
• STONE NL, MURPHY AJ, ENGLAND TJ and O'SULLIVAN SE, 2020. A Systematic Review of Minor Phytocannabinoids with Promising Neuroprotective Potential Br J Pharmacol. 177(19), 4330-4352
• BENFIELD JK, MICHOU E, EVERTON LF, MILLS C, HAMDY S, BATH PM and ENGLAND TJ, 2020. The Landscape of Videofluoroscopy in the UK: A Web-Based Survey Dysphagia. 32417980
• LAW ZK, DINEEN R, ENGLAND TJ, CALA L, MISTRI AK and ET AL, 2020. Predictors and Outcomes of Neurological Deterioration in Intracerebral Hemorrhage: Results from the TICH-2 Randomized Controlled Trial. Transl Stroke Res. PMID: 32902808
• APPLETON JP, O'SULLIVAN SE, HEDSTROM A, MAY JA, DONNELLY R, SPRIGG N, BATH PM and ENGLAND TJ, 2020. Blood markers in remote ischaemic conditioning for acute ischaemic stroke: data from the REmote ischaemic Conditioning After Stroke Trial Eur J Neurol.
• WARDLAW J, BATH PMW, DOUBAL F, HEYE A, SPRIGG N, WOODHOUSE LJ, BLAIR G, APPLETON J, CVORO V, ENGLAND T, HASSAN A, WERRING DJ, MONTGOMERY A and THE LACI-2 TRIAL INVESTIGATORS, 2020. Protocol: The Lacunar Intervention Trial 2 (LACI-2). A trial of two repurposed licenced drugs to prevent progression of cerebral small vessel disease (In Press.)
• WEIR P, MAGUIRE R, O'SULLIVAN S and ENGLAND TJ, 2020. A Meta-analysis of Remote Ischaemic Conditioning in Experimental Stroke J Cereb Blood Flow Metab. 41(1), 32538284
• THE RIGHT-2 INVESTIGATORS, 2019. Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial. Lancet (London, England). (In Press.)
• SPRIGG N, FLAHERTY K, APPLETON JP, AL-SHAHI SALMAN R, BERECZKI D, BERIDZE M, CICCONE A, COLLINS R, DINEEN RA, DULEY L, EGEA-GUERRERO JJ and ENGLAND TJ, 2019. Tranexamic acid to improve functional status in adults with spontaneous intracerebral haemorrhage: the TICH-2 RCT Health Technol Assess. 23(35), 1-48
• MILLAR SA, STONE NL, BELLMAN ZD, YATES AS, ENGLAND TJ and O'SULLIVAN SE, 2019. A systematic review of cannabidiol dosing in clinical populations Br J Clin Pharmacol. (In Press.)
• STONE NL, ENGLAND TJ and O'SULLIVAN SE, 2019. A novel transwell blood brain barrier model using primary human cells Front Cell Neurosci. 13, 230
• BATH PM, APPLETON JP and ENGLAND T, 2019. Treatment of acute stroke: the hazard of negative (not neutral) trials. A review JAMA Neurology.
• ENGLAND TJ, HEDSTROM A, O’SULLIVAN SE, WOODHOUSE L, JACKSON B, SPRIGG N and BATH PM, 2019. Remote Ischaemic Conditioning After Stroke Trial 2: a phase IIb randomised controlled trial in hyperacute stroke J Am Heart Assoc. 8(23), e013572
• LAW ZK, ALI A, KRISHNAN K, BISCHOFF A, APPLETON JP, SCUTT P, WOODHOUSE L, PSZCZOLKOWSKI S, CALA LA, DINEEN RA, ENGLAND TJ, OZTURK S, ROFFE C, BERECZKI D, CICCONE A, CHRISTENSEN H, OVESEN C, BATH PM, SPRIGG N and TICH-2 INVESTIGATORS, 2019. Noncontrast CT signs as predictors of hematoma expansion, clinical outcome and response to tranexamic acid in acute ICH Stroke. 51, 121-128
• BATH PM, WOODHOUSE LJ, KRISHNAN K, APPLETON JP, ANDERSON CS, BERGE E, CALA L, DIXON M, ENGLAND TJ, GOLDOLPHIN PJ and ET AL, 2019. Pre-hospital transdermal glyceryl trinitrate for ultra-acute intracerebral haemorrhage- data from the RIGHT-2 trial Stroke. 50, 3064-3071
• DINEEN RA, PSZCZOLKOWSKI S, FLAHERTY K, LAW Z, MORGA PS, ROBERTS I, WERRING D, AL-SHAHI SALMAN R, AL-SHAHI SALMAN R, ENGLAND T, BATH PM and SPRIGG N, 2018. Does tranexamic acid lead to changes in MRI-measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? Protocol for a MRI sub-study nested within the double-blind randomised controlled TICH-2 trial BMJ Open. 8(2), e019930
• SULTAN SR, MILLAR SA, O'SULLIVAN SE and ENGLAND TJ, 2018. A Systematic Review and Meta-Analysis of the In Vivo Haemodynamic Effects of Δ⁸-Tetrahydrocannabinol. Pharmaceuticals (Basel, Switzerland). 11(1),
• SPRIGG N, FLAHERTY K, APPLETON JP, AL-SHAHI SALMAN R, BERECZKI D, BERIDZE M, CHRISTENSEN H, CICCONE A, COLLINS R, CZLONKOWSKA A, DINEEN RA, DULEY L, EGEA-GUERRERO JJ, ENGLAND TJ, KRISHNAN K, LASKA AC, LAW ZK, OZTURK S, POCOCK SJ, ROBERTS I, ROBINSON TG, ROFFE C, SEIFFGE D, SCUTT P, THANABALAN J, WERRING D, WHYNES D and BATH PM, 2018. Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial Lancet. 391(10135), 2107-2115
• BENFIELD JK, EVERTON LF, BATH PM and ENGLAND TJ, 2018. Does Therapy With Biofeedback Improve Swallowing in Adults With Dysphagia? A Systematic Review and Meta-Analysis. Archives of physical medicine and rehabilitation. (In Press.)
• BATH PM, WOODHOUSE LJ, APPLETON JP, BERIDZE M, CHRISTENSEN H, DINEEN RA, FLAHERTY K, DULEY L, ENGLAND TJ, HAVARD D, HEPTINSTALL S, JAMES M, KASONDE C, KRISHNAN K, MARKUS HS, MONTGOMERY AA, POCOCK S, RANDALL M, RANTA A, ROBINSON TG, SCUTT P, VENABLES GS and SPRIGG N, 2018. Triple versus guideline antiplatelet therapy to prevent recurrence after acute ischaemic stroke or transient ischaemic attack: the TARDIS RCT. Health technology assessment (Winchester, England). 22(48), 1-76
• BATH, P. M., WOODHOUSE, L. J., APPLETON, J. P., BERIDZE, M., CHRISTENSEN, H., DINEEN, R. A., DULEY, L., ENGLAND, T. J., FLAHERTY, K., HAVARD, D., HEPTINSTALL, S., JAMES, M., KRISHNAN, K., MARKUS, H. S., MONTGOMERY, A. A., POCOCK, S. J., RANDALL, M., RANTA, A., ROBINSON, T. G., SCUTT, P., VENABLES, G. S. and SPRIGG, N., 2018. Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial: Lancet Lancet. 391(10123), 850-859
• ENGLAND TJ, HEDSTROM A, O'SULLIVAN S, DONNELLY R, BARRETT DA, SARMAD S, SPRIGG N and BATH PM, 2017. RECAST (Remote Ischemic Conditioning After Stroke Trial): A Pilot Randomized Placebo Controlled Phase II Trial in Acute Ischemic Stroke. Stroke. 24(8), 81 (In Press.)
• BATH PM, MAY J, FLAHERTY K, WOODHOUSE LJ, DOVLATOVA N, FOX SC, ENGLAND TJ, KRISHNAN K, ROBINSON TG, SPRIGG N, HEPTINSTALL S and TARDIS INVESTIGATORS, 2017. Remote assessment of platelet function in patients with acute stroke or transient ischaemic attack Stroke Research and Treatment. 7365684
• SULTAN SR, MILLAR SA, ENGLAND TJ and O'SULLIVAN SE, 2017. A Systematic Review and Meta-Analysis of the Haemodynamic Effects of Cannabidiol Front Pharmacol. 24(8), 81
• APPLETON JP, SCUTT P, DIXON M, HOWARD H, HAYWOOD L, HAVARD D, HEPBURN T, ENGLAND T, SPRIGG N, WOODHOUSE LJ, WARDLAW JM, MONTGOMERY AA, POCOCK S, BATH PM and , 2017. Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: Rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053). International journal of stroke : official journal of the International Stroke Society. 1747493017724627 (In Press.)
• MILLAR SA, PATEL H, ANDERSON SI and ENGLAND TJ, 2017. Osteocalcin, vascular calcification and atherosclerosis: a systematic review and meta-analysis Front Endocrinol (Lausanne). 31(8), 183
• MAXWELL AE, MACLEOD MJ, JOYSON A, JOHNSON S, RAMADAN H, BELLFIELD R, BYRNE A, MCGHEE C, RUDD A, PRICE F, VASILEIADIS E, HOLDEN M, HEWITT J, CARPENTER M, NEEDLE A, VALENTINE S, PATEL F, HARRINGTON F, MUDD P, EMSLEY H, GREGARY B, KANE I, MUIR K, TIWARI D, OWUSU-AGYEI P, TEMPLE N, SEKARAN L, RAGAB S, ENGLAND T, HEDSTROM A, JONES P, JONES S, DOHERTY M, MCCARRON MO, COHEN DL, TYSOE S and AL-SHAHI SALMAN R, 2017. Reasons for non-recruitment of eligible patients to a randomised controlled trial of secondary prevention after intracerebral haemorrhage: observational study. Trials. 18(1), 162
• SPRIGG, N, ROBSON, K, BATH, P, DINEEN, R, ROBINSON, T, ROFFE, C, WERRING, D, AL-SHAHI SALMAN, R, POCOCK, S, DULEY, L, ENGLAND, TJ, WHYNES, D, CICCONE, A, LASKA, AC, CHRISTENSEN, H, OZTURK, S, COLLINS, R, BERECZKI, D, EGEA-GUERRERO, JJ, LAW, ZK, CZLONKOWSKA, A, SEIFFGE, D and BEREDZIE, M, 2016. Intravenous tranexamic acid for hyperacute primary intracerebral hemorrhage: Protocol for a randomized, placebo-controlled trial International Journal of Stroke. In Press,
• GHASEMI R, ROWE A, SHAH R, VENKATESAN P and ENGLAND TJ, 2016. Neurocysticercosis presenting as a 'Stroke Mimic'. Acute medicine. 15(2), 79-83
• SPRIGG N, O'CONNOR R, WOODHOUSE L, KRISHNAN K, ENGLAND TJ, CONNELL LA, WALKER MF and BATH PM, 2016. Granulocyte Colony Stimulating Factor and Physiotherapy after Stroke: Results of a Feasibility Randomised Controlled Trial: Stem Cell Trial of Recovery EnhanceMent after Stroke-3 (STEMS-3 ISRCTN16714730). PloS one. 11(9), e0161359
• TIMOTHY J ENGLAND, NIKOLA SPRIGG, ANDREY M. ALASHEEV, ANDREY A. BELKIN, AMIT KUMAR, KAMESHWAR PRASAD and PHILIP M. BATH, 2016. Granulocyte-Colony Stimulating Factor (G-CSF) for stroke: an individual patient data meta- analysis Scientific Reports. 15(6), 36567
• BATH PM, APPLETON JP, BERIDZE M, CHRISTENSEN H, DINEEN RA, DULEY L, ENGLAND TJ, HEPTINSTALL S, JAMES M, KRISHNAN K, MARKUS HS, POCOCK S, RANTA A, ROBINSON TG, FLAHERTY K, SCUTT P, VENABLES GS, WOODHOUSE LJ and SPRIGG N, 2016. Baseline characteristics of the 3096 patients recruited into the 'Triple Antiplatelets for Reducing Dependency after Ischemic Stroke' trial. International journal of stroke : official journal of the International Stroke Society. (In Press.)
• THOMAS SA, COATES E, DAS NAIR R, LINCOLN NB, COOPER C, PALMER R, WALTERS SJ, LATIMER NR, ENGLAND TJ, MANDEFIELD L, CHATER T, CALLAGHAN P and DRUMMOND AE, 2016. Behavioural Activation Therapy for Depression after Stroke (BEADS): a study protocol for a feasibility randomised controlled pilot trial of a psychological intervention for post-stroke depression. Pilot and feasibility studies. 2, 45
• BATH PMW, APPLETON JP, BERIDZE M, CHRISTENSEN H, DINEEN RA, DULEY L, ENGLAND T, HEPTINSTALL S, JAMES M, KRISHNAN K, MARKUS HS, POCOCK S, RANTA A, ROBINSON TG, FLAHERTY K, SCUTT P, VENABLES GS and WOODHOUSE LJ, 2016. Baseline characteristics of the 3,096 patients recruited into the Triple Antiplatelets for Reducing Dependency after Ischaemic Strok (TARDIS) trial International Journal of Stroke. (In Press.)
• HIND, WH, ENGLAND, TJ and O'SULLIVAN, SE, 2016. Cannabidiol protects an in vitro model of the blood brain barrier (BBB) from oxygen-glucose deprivation via PPARγ and 5-HT1A British Journal of Pharmacology. 173(5), 815-825
• ENGLAND TJ, HIND WH, RASID NA and O'SULLIVAN SE, 2015. Cannabinoids in experimental stroke: a systematic review and meta-analysis. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 35(3), 348-58
• HIND WH, TUFARELLI C, NEOPHYTOU M, ANDERSON SI, ENGLAND TJ and O'SULLIVAN SE, 2015. Endocannabinoids modulate human blood-brain barrier permeability in vitro. British journal of pharmacology. 172(12), 3015-3027
• M DE NUNZIO and T J ENGLAND, 2014. Pathogenesis of atherosclerosis and methods of arterial and venous assessment. In: TIM ENGLAND and AKHTAR NASIM, eds., ABC of Arterial and Venous Disease 3rd. Wiley Blackwell. 1-8
• T J ENGLAND, N ALTAF and S MACSWEENEY, 2014. Cerebrovascular and carotid artery disease. In: TIM ENGLAND and AKHTAR NASIM, eds., ABC of Arterial and Venous Disease 3rd. Wiley Blackwell. 9-16
• TIM ENGLAND and AKHTAR NASIM, eds., 2014. ABC of Arterial and Venous Disease 3rd. Wiley Blackwell.
• ENGLAND, T.J., BATH, P.M.W., ABAEI, M., AUER, D. and JONES, D.R.E., 2013. Hematopoietic stem cell (CD34+) uptake of superparamagnetic iron oxide is enhanced by but not dependent on a transfection agent Cytotherapy: Journal of Cell Therapy. 15(3), 384-390
• BATH, P.M.W., SPRIGG, N. and ENGLAND, T., 2013. Colony stimulating factors (including erythropoietin, granulocyte colony stimulating factor and analogues) for stroke Cochrane Database of Systematic Reviews. 2013(6), 1-44
• GILLIAN M SARE, ANDREW GHADAMI, SANDEEP ANKOLEKAR, TIMOTHY ENGLAND, FIONA HAMMONDS, MARGARET ADRIAN, JUDITH CLARKE, LYNN STOKES, DOROTHEE AUER and PHILIP MW BATH, 2013. Effect of Telmisartan on Cerebral and Systemic Haemodynamics in Patients with Recent Ischaemic Stroke: A Randomised Controlled Trial ISRN Stroke. 2013, 587954
• ENGLAND, T.J., ABAEI, M., AUER, D.P., LOWE, J., JONES, D.R.E., SARE, G., WALKER, M. and BATH, P.M.W., 2012. Granulocyte-colony stimulating factor for mobilizing bone marrow stem cells in subacute stroke: the Stem Cell Trial Of Recovery Enhancement After Stroke 2 Randomized Controlled Trial Stroke. 43(2), 405-411
• PMW BATH, S ANKOLEKAR, TJ ENGLAND and N SPRIGG, 2012. Acute treatment and prevention of stroke Clinical Medicine. 12, s69-s72
• GEEGANAGE, C., TRACY, M., ENGLAND, T., SARE, G., MOULIN, T., WOIMANT, F., CHRISTENSEN, H., DE DEYN, P.P., LEYS, D., O'NEILL, D., RINGELSTEIN, E.B. and BATH, P.M.W., 2011. Relationship between baseline blood pressure parameters (including mean pressure, pulse pressure, and variability) and early outcome after stroke: data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST) Stroke. 42(2), 491-493
• ENGLAND, T.J., BATH, P.M.W., SARE, G.M., GEEGANAGE, C., MOULIN, T., O'NEILL, D., WOIMANT, F., CHRISTENSEN, H., DE DEYN, P., LEYS, D. and RINGELSTEIN, E.B., 2010. Asymptomatic hemorrhagic transformation of infarction and its relationship with functional outcome and stroke subtype: assessment from the Tinzaparin in Acute Ischaemic Stroke Trial Stroke. 41(12), 2834-2839
• ALCOCK, JOELLE, LOWE, JAMES, ENGLAND, TIM, BATH, PHILIP and SOTTILE, VIRGINIE, 2009. Expression of Sox1, Sox2 and Sox9 is maintained in adult human cerebellar cortex. Neuroscience Letters. 450(2), 114-6
• BATH, and ENGLAND,, 2009. Thigh-length compression stockings and DVT after stroke. Lancet. 373(9679), 1958-65
• ENGLAND, T.J., GIBSON, C.L. and BATH, P.M.W., 2009. Granulocyte-colony stimulating factor in experimental stroke and its effects on infarct size and functional outcome: a systematic review Brain Research Reviews. 62(1), 71-82
• ENGLAND T, MARTIN P and BATH PMW, 2009. Stem Cells For Enhancing Recovery After Stroke: A Review. International Journal Of Stroke : Official Journal Of The International Stroke Society. 4(2), 101-10
• SARE, G.M., BATH, P.M.W., GRAY L.J., MOULIN, T., WOIMANT, F., ENGLAND, T., GEEGANAGE, C., CHRISTENSEN, H., DE DEYN, P.P., LEYS, D., O'NEILL, D. and RINGELSTEIN, E.B., 2009. The relationship between baseline blood pressure and computed tomography findings in acute stroke: data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST) Stroke. 40(1), 41-46
• SPRIGG, N., GRAY, L.J., ENGLAND, T., WILLMOT, M.R., ZHAO, L., SARE, G.M. and BATH, P.M.W., 2008. A randomised controlled trial of triple antiplatelet therapy (aspirin, clopidogrel and dipyridamole) in the secondary prevention of stroke: safety, tolerability and feasibility PLoS ONE. 3(8), e2852
• ENGLAND R, ENGLAND T and COGGON J, 2007. The Ethical And Legal Implications Of Deactivating An Implantable Cardioverter-Defibrillator In A Patient With Terminal Cancer. Journal Of Medical Ethics. 33(9), 538-40
• SULTAN SR, MILLAR SA, O'SULLIVAN SE and ENGLAND TJ, A Systematic Review and Meta-Analysis of the in Vivo Haemodynamic Effects of Δ9-Tetrahydrocannabinol Pharmaceuticals. (In Press.)
• BENFIELD JK, EVERTON LF, BATH PM and ENGLAND TJ, Accuracy and clinical utility of Nurse Dysphagia Assessments: a systematic review Journal of Clinical Nursing. (In Press.)
• STROMSNES TA, KAUGERUD HAGEN TJ, OUYANG M, WANG X, CHEN C, RYGG SE, HEWSON D, LENTHALL R, MCCONACHIE N, IZZATH W, BATH PM, DHILLON PS, PODLASEK A, ENGLAND T, SPRIGG N, ROBINSON TG, ADVANI R, IHLE-HANSEN H, SANDSET EC and KRISHNAN K, Pressor therapy in acute ischaemic stroke: an updated systematic review Euro Stroke J. 7(2), 99-116
• SULTAN, S. R., MILLAR, SA AUID-ORCID, O'SULLIVAN, S. E. and ENGLAND, TJ AUID-ORCID, A Systematic Review and Meta-Analysis of the In Vivo Haemodynamic Effects of Delta(8)-Tetrahydrocannabinol. LID - E13 [pii] LID - 10.3390/ph11010013 [doi]