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Division of Rheumatology, Orthopaedics and Dermatology

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David Walsh

Director, Arthritis Research UK Pain Centre, Faculty of Medicine & Health Sciences

Contact

  • workRoom A19, Academic Rheumatology Clinical Sciences Building
    Nottingham City Hospital
    Hucknall Road
    Nottingham
    NG5 1PB
    UK
  • work0115 823 1751
  • fax0115 823 1757

Biography

David Walsh is Professor of Rheumatology at the University of Nottingham and Consultant Rheumatologist at Sherwood Forest Hospitals NHS Foundation Trust. In 2010 he established the Arthritis Research UK Pain Centre in Nottingham, together with a multidisciplinary research team which includes preclinical neurosciences, psychology, neuroimaging, orthopaedics, genetics, epidemiology and evidence synthesis. The Centre aims to develop new and improved treatments through a translational research programme into the mechanisms by which changes within the joint and in the nervous system interact with psychosocial factors to produce arthritis pain. His preclinical research has focused on structural changes that contribute to joint pain, in particular angiogenesis, nerve growth, inflammation and matrix turnover in the synovium and subchondral bone. His clinical research is defining the spectrum of pain phenotypes in people with arthritis based on underlying pain mechanisms, in order to better target treatments to those most likely to benefit. In 2017 he became the first lead for the Musculoskeletal Theme at the launch of the NIHR Nottingham Biomedical Research Centre and represents Nottingham on the NIHR musculoskeletal Translational Research Collaboration. He was a member of the Guideline Development Group for NICE guidelines on the management of low back pain and sciatica, and continues clinical practice in rheumatology and low back pain.

Research Summary

Director of the Arthritis Research UK Pain Centre.

A programme of laboratory research complements other activities within Academic Rheumatology, exploring the interdependance of pain and neurovascular plasticity in joint disease. The group uses a range of molecular, histomorphometric and pharmacological techniques to characterise the nature, causes and consequences of blood vessel and nerve growth in the joint's synovial lining, bone and cartilage.

Selected Publications

School of Medicine

University of Nottingham
Medical School
Nottingham, NG7 2UH

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