Dr Catherine Kaylor-Hughes studied at the University of Sussex and achieved her BSc Hons in Neuroscience in 2000. She then went on to study at Sussex for her DPhil in Neuroscience from 2000-2003, before working at the University of Sheffield from 2003-2010 as a post-doctoral researcher in the Sheffield Cognition and Neuroimaging Laboratory (SCANLab). After this she came to the University of Nottingham as a research fellow for the CLAHRC-NDL until its completion in December 2013.
Catherine is currently working as the Mental Health Theme Clinical Trial Manager on several studies within the new CLAHRC - East Midlands and is research lead on a trial of online interventions for Depression and Anxiety. She is also part of the imaging analysis team on a multi-centre NIHR EME Funded RCT comparing connectivity guided TBS with repetitive TMS in treatment resistant depression.
Catherine's research interests lie in finding earlier treatments and providing better accessibility to mental health care and wellbeing through pragmatic, cost effective and clinically significant trials and interventions. More specifically she has managed research into the effectiveness of interventions with a view to timely implementation into NHS practice in the long term for depression and anxiety, health anxiety, ADHD, and Self-Harm.
Working within the Collaboration for Leadership and Applied Health Research and Care (CLAHRC-EM), Catherine has expertise in designing complex clinical and pragmatic trials that include mixed method designs, digital technology applications and randomised controlled trials; all of which require coordination of effective outcomes through implementation frameworks and strong stakeholder networks.
She also has significant experience of the design of imaging protocols for use in functional and structural MRI trials in health and disease. She is an experienced user of SPM and has recently begun to integrate FSL protocols in image processing for the purposes of identifying sites for connectivity guided TMS.
Catherine has taught on a number undergraduate and postgraduate courses throughout her career so far including:
MSc - Molecular Aspects of Brain Disease; Molecular Medicine course module 'Neuropsychiatry and NeuroImaging; MSc - Visual and Auditory Evoked Response Potentials.
Year 4 Medical - Design and Application of Structural and Functional Brain Imaging
BSc Evolution, Sensory Systems and Physiology and Behaviour
Supervision: Masters Research; BMedSci (Phase 1b); UG Community Internship Aspire to Go Further; Research into Practice (RIPIples)
Mentoring: University Staff Mentor of Research Associates
Dr Kaylor-Hughes' main research interests are within neuroscience, cognitive psychology and mental health.
More recently her research has focussed on applied healthcare clinical trials within Mental Health. Here Catherine provides oversight of the mental health studies running within the CLAHRC East Midlands, consulting with the research teams to help shape the design, implementation and maintenance of RCT clinical studies that are testing a number of methodologies and interventions including:
- - Therapy through video conferencing to reduce symptoms of distress in people using Urgent Care Services
- - Technology to reduce time to diagnosis in ADHD
- - Remote therapy to help young people who Self-Harm
- - Online Interventions for Depression and Anxiety - A Public Health Approach
KAPIL SAYAL, JAMES ROE, HARRIET BALL, CHRISTOPHER ATHA, CATHERINE KAYLOR-HUGHES, BOLIANG GUO, ELLEN TOWNSEND and RICHARD MORRISS, 2019. Feasibility of a randomised controlled trial of remotely delivered problem-solving cognitive behaviour therapy versus usual care for young people with depression and repeat self-harm: lessons learnt (e-DASH). BMC Psychiatry. (In Press.)
THOMSON L, BARKER M, KAYLOR-HUGHES CJ, GARLAND A, RAMANA R, MORRISS R, HAMMOND, E, HOPKINS, G and SIMPSON, S, 2018. How is a Specialist Depression Service effective for persistent moderate to severe depressive disorder? A qualitative study of service user experience BMC Psychiatry. 18, 194 CHRIS HOLLIS, CHARLOTTE L. HALL, BOLIANG GUO, MARILYN JAMES, JANET BOADU, MADELEINE J. GROOM, NIKKI BROWN, CATHERINE KAYLOR‐HUGHES, MARIA MOLDAVSKY, ALTHEA Z. VALENTINE, GEMMA M. WALKER, DAVID DALEY, KAPIL SAYAL, RICHARD MORRISS, SARAH CURRAN, JULIE CLARKE, SAMINA HOLSGROVE, TERESA JENNINGS, NEETA KULKARNI, MARIA MOLDAVSKY, DILIP NATHAN, ANNE‐MARIE SKARSTAM, KIM SELBY, HENA VIJAYAN and ADRIAN WILLIAMS, 2018. The impact of a computerised test of attention and activity (QbTest) on diagnostic decision‐making in children and young people with suspected attention deficit hyperactivity disorder: single‐blind randomised controlled trial Journal of Child Psychology and Psychiatry. 0(0),
GUO B, KAYLOR-HUGHES C, GARLAND A, NIXON N, SWEENEY T, SIMPSON S, DALGLEISH T, RAMANA R, YANG M and MORRISS R, 2017. Factor structure and longitudinal measurement invariance of PHQ-9 for specialist mental health care patients with persistent major depressive disorder: Exploratory Structural Equation Modelling. Journal of affective disorders. 219, 1-8