Clare is a Senior Trial Manager (STM) and has worked in clinical trial research since 2013. Clare started her career working for a clinical research organisation during which she gained experience in the development of Investigational Medicinal Products (IMPs) and the management of phase I and II clinical trials in healthy and patient populations.
In 2019 Clare started working at the Nottingham Clinical Trials Unit and to date has managed a number of multi-centre phase III trials in a wide range of areas including oncology, obstetrics and gynecology, neonatal medicine, and viral infection (Covid-19).
Clare currently teaches the Approvals and Regulations session of a short course designed and delivered by the Nottingham Clinical Trials Unit; "Fundamentals of Clinical Trials". More about the course… read more
Clare is currently the STM for the POISE, STADIA, SATURN and BLUSH clinical trials:
POISE: Hormone therapy for premature ovarian insufficiency (POI): randomised trial and long-term evaluation
STADIA: STAndardised DIagnostic Assessment for children and adolescents with emotional difficulties (STADIA): a multi-centre randomised controlled trial
SATURN: Stimulant Medication for ADHD and Tics - Understanding Response versus Non-stimulants (SATURN): a randomised trial of the clinical and cost-effectiveness of methylphenidate versus Guanfacine for ADHD in children and young people with a co-existing tic disorder
BLUSH: Oxybutynin or venlafaxine for hot flushes in women who cannot or choose not to use hormone replacement therapy: randomised trial and economic evaluation
TAI, HY, UPTON, CE, WHITE, LJ, PINI, R, STORTI, G, MAZZOTTI, M, SHAKESHEFF, KM and HOWDLE, SM, 2010. Studies On The Interactions Of Co2 With Biodegradable Poly(Dl-Lactic Acid) And Poly(Lactic Acid-Co-Glycolic Acid) Copolymers Using High Pressure Atr-Ir And High Pressure Rheology Polymer. 51(6), 1425-1431 KANCZLER, JM, MIRMALEK-SANI, SH, HANLEY, NA, IVANOV, AL, BARRY, JJA, UPTON, C, SHAKESHEFF, KM, HOWDLE, SM, ANTONOV, EN, BAGRATASHVILI, VN, POPOV, VK and OREFFO, ROC, 2009. Biocompatibility And Osteogenic Potential Of Human Fetal Femur-Derived Cells On Surface Selective Laser Sintered Scaffolds Acta Biomaterialia. 5(6), 2063-2071
BARRY, JJA, EVSEEV, AV, MARKOV, MA, UPTON, CE, SCOTCHFORD, CA, POPOV, VK and HOWDLE, SM, 2008. In Vitro Study Of Hydroxyapatite-Based Photocurable Polymer Composites Prepared By Laser Stereolithography And Supercritical Fluid Extraction Acta Biomaterialia. 4(6), 1603-1610