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Clive Adams

Co-ordinating Editor, Cochrane Schizophrenia Group, Faculty of Medicine & Health Sciences



Born: Northern Ireland - where the Morne Mountains sweep down to the seaMourne Mountains.

Qualified: Medicine (Queen's University Belfast 1983); Psychiatry (Royal College of Psychiatrists, London 1989); Epidemiology (London School of Hygiene and Tropical Medicine, London 1991)

Psychiatry: Bradford, London, Oxford, Leeds, Nottingham, UK.

Research: Based in London, Oxford, Leeds, Nottingham, UK but trials undertaken with collaborators in Australia, Brazil, China, India, reviews with people in 21 different countries.

Working: Institute of Mental Health, University of Nottingham, UK.

Institute of Mental Health, Nottingham

Aspirations: to help do better trials, better reviews - particularly for those relevant to people with schizophrenia - and for that process to be more driven by needs of people living with schizophrenia than might have been the case some years ago.

Expertise Summary

I have expertise in the evaluation of the care of people living with schizophrenia - synthesis of trial data into systematic reviews, and randomised trials - especially those with a focus on management in situations of limited resource. I am interested in medical informatics and have experience of biomedical search techniques, and using machines to help surmise evidence.

Teaching Summary

A. Systematic reviewing

This may take the form of face to face teaching, group work or distance learning.

For example, in 2014 our group has run workshops in

  • Nottingham, UK,
  • Shanghai and Beijing, China
  • Kuala Lumpur, Malaysia
  • Kermān, Iran (via Skype)

Next year, workshops are planned in China, Malaysia, Egypt and the UK.

B. Evidence-based practice

These workshops are run with a problem-based learning ethos.

In 2014 we ran one workshop for surgeons in China.

Research Summary

  1. Pragmatic randomised trials - in Finland - Trial of mobile phone messaging for people who need to continue to take antipsychotic drugs (ISRCTN27704027)
  2. Randomised trial of systematic reviews in Twitter (ISRCTN84658943)
  3. Dental intervention relevant to care of people with schizophrenia (ISRCTN63382258)
  4. Evaluating zuclopenthixol acetate versus haloperidol plus promethazine for people whose aggression is thought due to psychotic illness (India)


  1. Many Cochrane reviews relevant to people with schizophrenia - please see Cochrane Library.


  1. Production of review writing software
  2. Study-based registers of trials

Selected Publications

Past Research


  1. Trials evaluating drug treatment of people whose aggression is thought due to psychotic illness (Brazil X 2, India X 2)
  2. Trial of restraints versus seclusion room for people whose aggression is thought due to psychotic illness (Brazil)


  1. Author on 33 Cochrane reviews.


  1. Searching strategies in different databases
  2. Automatic writing of reviews

Future Research


  1. Early warning signs for relapse in schizophrenia


  1. Many ongoing relevant to care of people with schizophrenia - for example group of reviews relevant to management of Tardive Dyskinesia


  1. Auto document optimisation to enhance accuracy of data extraction
  2. Auto data extraction from PDF
  3. Auto data storage and curation
  4. Auto data assimilation and report writing
  5. Provision of all such work into the hands of anyone in need of high quality current data on effects of care.

School of Medicine

University of Nottingham
Medical School
Nottingham, NG7 2UH

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