Kareem is a PhD researcher at the Institute of Mental Health at the University of Nottingham. Along with his supervisor Professor Cris Glazebrook, they have recently completed a process evaluation of the Online Remote Behavioural Intervention for Tics (ORBIT) trial for young people with a diagnosis of Tourette Syndrome or Chronic Tic Disorder.
A process evaluation examines the processes through which an intervention generates outcomes, that is, how they work. Kareem interviewed young people and their supporters who participated in the ORBIT trial to find out about their overall experience of the study, whether the intervention worked or not and if so, the mechanisms through which this was achieved. He also analysed quantitative data from the trial to investigate engagement with the intervention.
Prior to this, he worked for many years as an Assistant Psychologist and then as a Research Assistant in a range of different settings, including a specialist neurology clinic, the Priory Hospital, and a brain injury rehabilitation unit. Kareem completed a BSc (Hons) in Psychology and an MSc in Psychological Research Methods at the University of Plymouth. He has a keen interest in neurodevelopmental disorders and neuropsychology and digital mental health.
Digital Health Interventions
Kareem is currently Research Associate on the ORBIT trial. The aim of this study was to assess the clinical and cost-effectiveness of a remotely delivered therapist-guided, parent-assisted digital… read more
KHAN K, HOLLIS C, HALL CL, DAVIES EB, MATAIX-COLS D, ANDRÉN P, MURPHY T, BROWN BJ, MURRAY E and GLAZEBROOK C, 2020. Protocol for the Process Evaluation of the Online Remote Behavioural Intervention for Tics (ORBIT) randomized controlled trial for children and young people: Trials Trials. 21(1), 6
SCHRAG, A., KHAN, K., HOTHAM, S., MERRITT, R., RASCOL, O. and GRAHAM, L., 2018. Experience of care for Parkinson's disease in European countries: a survey by the European Parkinson's Disease Association: European Journal of Neurology European Journal of Neurology. 25(12), 1410-e120
Kareem is currently Research Associate on the ORBIT trial. The aim of this study was to assess the clinical and cost-effectiveness of a remotely delivered therapist-guided, parent-assisted digital behavioural intervention (BiP TIC) for treating moderate and severe tics in children and adolescents with Tourette syndrome (TS) or chronic tic disorder (CTD). The trial was a single-blind parallel-group randomised, controlled, superiority trial of treatment as usual (TAU) + remote therapist-guided digital behavioural intervention (BiP TIC) compared to active control (TAU + remote online education and therapist support without BiP TIC), in children and young people (aged 9-17) with TS or CTD. The trial recruited nationally from CAMHS and community paediatrics, via the national charity Tourettes Action and from specialist Tourette's clinics in England. The intervention was delivered remotely from 2 regional centres in the Midlands/North (Queen's Medical Centre, Nottingham) and South of England (Great Ormond Street Hospital, London).
The ORBIT trial has now completed recruitment and the majority of the follow-up assessments. The findings will be reported in due course. My role involves working on the implementation of ORBIT in routine healthcare.
My previous research extends across multiple disciplinary fields, but primarily lies in applied psychology and neurology.
My PhD work focussed on the process evaluation of the ORBIT trial. A process evaluation examines the processes through which an intervention generates outcomes, that is, how they work, and also investigates the quality of what was delivered (i.e. according to protocol). In doing so, it is able to capture implementation fidelity, the mechanisms of impact, and contextual factors. This was a mixed-methods design using quantitative data from the ORBIT trial together with semi-structured interviews with participants, therapists, and clinicians involved in the study.
Prior to this, I worked as a Research Assistant at the University College London (UCL) Queen Square Institute of Neurology working on a range of studies involving patients with Parkinson's Disease. This involved carrying out assessments, administering psychometric tests, and preparing manuscripts for publications.