Natural Sciences
   
   
  

Environmental Science, Biological Sciences and Chemistry

Natural Sciences is a multidisciplinary degree which allows you to study three subjects in the first year and continue with two subjects in the second and third year. The combination of subjects which you study in the first year allows you to find out what each subject is like at university before you specialise further. You will also have the opportunity to explore specialist areas through optional modules as you progress through the course. Both of the subjects taken beyond the first year will be studied to degree level. This degree aims to provide you with a broad knowledge and understanding of your chosen areas of science, as well as experience of interdisciplinary study.

Year One

You will study 40 credits of each subject from your chosen three-subject pathway.

Environmental Science


40 compulsory credits:

  • Global Environmental Processes (20 credits, Autumn semester)
The unifying theme of this module is biogeochemical cycling - the production, distribution and cycling of materials on the Earth and their availability to, and use by, biological organisms. The module starts by covering the history of the universe, from the big bang to the evolution of the Earth's surface environment. Then you will explore the major global systems and their circulations as they are today - solids, liquids and gases. In the final section you will examine the major materials - including carbon, nitrogen, sulphur, oxygen and metals - and their budgets and cycles; and the interactions between biological and physical/chemical processes on a global scale. You will have a two-hour lecture once a week for this module. 
 
  • Environmental Geoscience (20 credits, Autumn semester)
Bulk properties of the Earth, minerals, igneous rocks, sedimentary rocks, metamorphic rocks, geological time, tectonics, geological structures, map interpretation, geological hazards, resource geology.
 
 

Biological Sciences


40 compulsory credits from your chosen subpathway:

Molecular and Cellular Biology subpathway

Genes, Molecules and Cells (40 credits, full year)
This module combines lectures and laboratory classes and introduces you to the structure and function of significant molecules in cells, and the important metabolic processes which occur inside them. You will study, amongst other topics, protein and enzyme structure and function, the biosynthesis of cell components, and the role of cell membranes in barrier and transport processes. You'll examine how information in DNA is used to determine the structure of gene products. Topics include DNA structure, transcription and translation and mutation and recombinant DNA technology.
 


Organismal Biology subpathway

Evolution, Ecology and Behaviour (20 credits, full year)
Starting with Darwin’s theory of evolution, you will learn how natural selection and other evolutionary forces have shaped the ways in which organisms interact with each other and their environment. In addition to lectures, practical classes will give you hands-on experience with a range of ecological and behavioural concepts in the laboratory and the field.
 
Life on Earth (20 credits, full year)
Life on Earth provides an introduction to the fundamental characteristics and properties of the myriad of organisms which inhabit our planet, from viruses, bacteria and Archaea, to plants and animals. In weekly lectures, and regular laboratory practical classes, you will consider how living organisms are classified, how they are related genetically and phylogenetically, and basic aspects of their structure and function.
 
 

Chemistry


40 compulsory credits:

Fundamental Chemistry Theory and Practical (40 credits, full year)
This module shows how trends in chemical properties can be related to the structure of the Periodic Table and rationalise descriptive inorganic chemistry. To provide a fundamental understanding of the basics of organic chemistry, including nomenclature, molecular structure and bonding, stereochemistry and the chemical reactivity of common functional groups and reaction types through an understanding of their electronic properties. To provide an introduction to fundamental physical aspects of chemistry, which underpins all areas of Chemistry - emphasis will be placed on being able to apply knowledge, especially in solving problems. To introduce a range of chemical techniques appropriate to the study of inorganic, organic and physical chemistry at first year level, which will act as a foundation for more advanced work in subsequent years.
 
 

 

Year Two

You will continue on a pathway comprising of two of your first year subjects. You will take 60 credits of modules from each subject and greater emphasis will be put on studying outside of formal classes.

Environmental Science


20 compulsory credits:

Climate Change Science (10 credits, Autumn semester)
A broad overview of the science behind climate change and its effects is studied on this module. Topics include: historical climate change; the principles of climate forcing; the role of modelling; responses of aquatic and terrestrial ecosystems, including impacts on humans; the political environment; and options for climate stabilisation. You will have a two-hour lecture once a week with complementary practical and computing classes.
 
Soil Science (10 credits, Autumn semester)
This is an introductory module which provides a basic understanding of the nature and properties of soil and the application of soil chemistry, biology and physics to land management and environmental science. At the end of the module, the students should: possess quantitative knowledge of the magnitude of common soil parameters; have a clear understanding of the inter-relationship of soil processes and be able to offer pragmatic advice on soil management to environmental and agronomic managers. You will have a three-hour lecture each week, ending in an online examination.
 

Compulsory with Biological Sciences

  • Ecosystem Processes (10 credits, Autumn semester)

The course will focus on the processes that govern terrestrial ecosystem function. We will identify key ecosystem drivers and processes and explore how these have shaped the biosphere. Students will gain an understanding of the mechanisms that control changes in the physiochemical environment and their impact upon communities. Particular topics will include primary productivity, decomposition, herbivory, biodiversity and human impact on ecosystems. Classes comprise a mix of lectures, laboratory practicals, a computer practical, a seminar and fieldwork

 
  • Environmental Management Field Course (10 credits, Autumn semester)
BSc Environmental Biology, Environmental Science students and Natural Sciences Environmental Science pathway. If you are a student with a disability, and you have not already disclosed your disability to the module convenor, you should discuss any needs you may have with the module convenor at the point of registering for this module. The University will take all reasonable steps to ensure that any student with a disability is able to access this module.
 


Compulsory with Chemistry

  • Soil and Water Science (20 credits, Spring semester)
The aim of the module is to provide a sound understanding of important physical and chemical processes that take place within soils and fresh water systems. This includes provide a basis for the understanding of more applied aspects of the behaviour of these systems (eg plant-soil interactions, pollution and its remediation).
 


Optional environmental science modules

A further 20 credits from the options below:

  • Ecosystem Processes (10 credits, Autumn semester)

The course will focus on the processes that govern terrestrial ecosystem function. We will identify key ecosystem drivers and processes and explore how these have shaped the biosphere. Students will gain an understanding of the mechanisms that control changes in the physiochemical environment and their impact upon communities. Particular topics will include primary productivity, decomposition, herbivory, biodiversity and human impact on ecosystems. Classes comprise a mix of lectures, laboratory practicals, a computer practical, a seminar and fieldwork

 
Environmental Management Field Course (10 credits, Autumn semester)
BSc Environmental Biology, Environmental Science students and Natural Sciences Environmental Science pathway. If you are a student with a disability, and you have not already disclosed your disability to the module convenor, you should discuss any needs you may have with the module convenor at the point of registering for this module. The University will take all reasonable steps to ensure that any student with a disability is able to access this module.
 
Soil and Water Science (20 credits, Spring semester)
The aim of the module is to provide a sound understanding of important physical and chemical processes that take place within soils and fresh water systems. This includes provide a basis for the understanding of more applied aspects of the behaviour of these systems (eg plant-soil interactions, pollution and its remediation).
 
Computer Modelling in Science: Introduction (20 credits, Spring semester)
The aim of this module is to introduce the use of computing programming and modelling in the biological and environmental sciences for model simulation and image processing.
 
 

Biological Sciences


40 compulsory credits from your chosen subpathway:

Molecular and Cellular Biology subpathway (option 1)

  • The Genome & Human Disease (20 credits, Autumn semester)

In this module you will learn about the structure and function of the eukaryotic genome, including that of humans, and the approaches that have led to their understanding. You will learn about techniques that are employed to manipulate genes and genomes and how they can be applied to the field of medical genetics. By using specific disease examples, you will learn about the different type of DNA mutation that can lead to disease and how they have been identified. Practical elements will teach you about basic techniques used in medical genetics such as sub-cloning of DNA fragments into expression vectors. Practical classes and problem based learning will be used to explore the methods used for genetic engineering and genome manipulation.

 
  • Animal Behaviour and Physiology (20 credits, Spring semester)
Introduces the study of animal behaviour, from the physiological and genetic bases of behaviour to its development and adaptive significance in the natural environment. You will have a three-hour lecture once per week for this module. 
 


Molecular and Cellular Biology subpathway (option 2)

The Genome & Human Disease (20 credits, Autumn semester)

In this module you will learn about the structure and function of the eukaryotic genome, including that of humans, and the approaches that have led to their understanding. You will learn about techniques that are employed to manipulate genes and genomes and how they can be applied to the field of medical genetics. By using specific disease examples, you will learn about the different type of DNA mutation that can lead to disease and how they have been identified. Practical elements will teach you about basic techniques used in medical genetics such as sub-cloning of DNA fragments into expression vectors. Practical classes and problem based learning will be used to explore the methods used for genetic engineering and genome manipulation.

 
Bacterial Genes and Development (10 credits, Spring semester)
Molecular events that occur during the control of gene expression in bacteria will be explored. You'll learn by considering case studies, which will show you how complex programmes of gene action can occur in response to environmental stimuli. You will also study the regulation of genes in pathogenic bacteria.
 
Microbial Biotechnology (10 credits, Spring semester)

You'll cover the key groups of eukaryotic and prokaryotic microorganisms relevant to microbial biotechnology, principles of GM, and strain improvement in prokaryotes and eukaryotes. The impact of “omics”, systems biology, synthetic biology and effects of stress on industrial microorganisms are explored, alongside the activities of key microorganisms that we exploit for biotechnology.

 


Organismal Biology subpathway

Ecology (20 credits, Autumn semester)

You will learn about the forces determining the distribution and abundance of species and be able to use models to predict the dynamics of populations under a range of conditions. You will recognise how interactions between species can drive co-evolutionary processes leading to an understanding of the organisation of natural systems working systematically from populations through to communities, ecosystems and biogeographical scales.

 
The Green Planet (20 credits, Spring semester)
This module explores the evolution of key plant systems through deep time, and the significance of this process for understanding modern ecology and food security. You will learn about the challenges that plants faced when moving onto land and evolutionary innovations within the early spermatophytes. You will also gain an understanding of the power of natural selection in producing plant diversity over deep time.
 


Optional biology modules

A further 20 credits from the options below:

Signalling & Metabolic Regulation (20 credits, full year)
This module will explain the main signalling mechanisms that take place in eukaryotic cells. You will learn about the main signalling mechanisms and pathways which can control protein levels, activity and intra-cellular site of action. This knowledge will then be placed in the context of the regulation of major metabolic pathways, such that you will understand the factors influencing metabolic control, and dysregulation leading to major modern diseases like type II diabetes and heart disease.
 
Building Brains (20 credits, Autumn semester)

Studying this module, you'll be able to explain how the nervous system develops, is organised, and processes information. This will be achieved through presentation of comparative invertebrate and vertebrate studies, consideration of evolutionary concepts, and a detailed analysis of the development, structure, and function of the mammalian brain. The lecture sessions are complemented by workshops on Drosophila and chick embryo development, on the neuroanatomy of the human spinal cord, and dissection of pig brains subject to the availability of tissue.

 
Infection & Immunity (20 credits, Autumn semester)

In this module you will study basic immunology, learning about the organs, cells and molecules of the immune system and the mechanisms engaged in the generation an of immune response to pathogens. You will learn by studying examples of types of human pathogens (viral, bacterial, fungal, protozoa and helminths), the varied nature of the immune response, depending on the pathogen, its niche(s) in the host and pathogen strategies for invading and surviving in the host. You will learn how immunological methods can be effectively utilized for disease diagnosis and vaccine development, and about the consequences of failure of normal immune function, including autoimmunity and hypersensitivity.

 
Neurones and Glia (20 credits, Autumn semester)

This module will provide you with an understanding of the mechanisms behind electrical conduction in neurones. You will learn about the generation of the membrane potential and its essential role in signaling within the nervous system. You will develop an appreciation of the role of ion channels in the generation of trans-membrane currents and how myelin can accelerate signal conduction. You will also learn about the important supporting roles that astrocytes and glial cells play in the nervous system in order to ensure its efficient functioning.

 
Structure, Function and Analysis of Proteins (20 credits, Autumn semester)

This module considers the structure and function of soluble proteins and how individual proteins can be studied in molecular detail. More specifically you will learn about the problems associated with studying membrane-bound proteins and build an in-depth understanding of enzyme kinetics and catalysis. You will learn about the practical aspects of affinity purification, SDS PAGE, western blotting, enzyme assays, bioinformatics and molecular modelling approaches.

 
Neurobiology of Disease (20 credits, Spring semester)

This module will teach you the underlying neurophysiology and pathology associated with several common CNS disorders and the neuropharmacology of currently available medication. You will learn about the neurotransmitters and pathways involved in normal brain function and how changes in these contribute to abnormal function. You will also decipher the pharmacological mechanisms of drugs used to treat these CNS disorders. You will cover numerous human diseases including those with great significance such as Alzheimer's disease, epilepsy, schizophrenia and autism.

 
Evolutionary Biology of Animals (10 credits, Autumn semester)
Introduces key evolutionary concepts and their application in the animal kingdom. Areas you will study include the history of evolutionary thinking, natural selection versus the neutral theory, sexual selection and human evolution. 
 
Developmental Biology (10 credits, Spring semester)
Examines the basic concepts of vertebrate embryonic development. You will discuss specific topics including germ cells, blood and muscle cell differentiation, left-right asymmetry and miRNAs. The teaching for this module is delivered through lectures. 
 
Molecular Imaging (10 credits, Spring semester)

This module enables you to develop an elementary understanding of modern molecular imaging techniques, in addition to a historical overview of microscopy. You will acquire theoretical and practical knowledge of how to localise and analyse macromolecule behaviours in fixed and living cells.

 
 

Chemistry


40 compulsory credits:

Core Laboratory Work 'N' (20 credits, full year)
This module builds on the practical, analytical and communication skills acquired in the first year and introduces more advanced experiments across inorganic, organic and physical chemistry (note – students choose 2 of the 3 from Inorganic, Organic and Physical Chemistry). Increasing use is made of spectroscopic and other analytical techniques in the characterisation of compounds. More detailed laboratory reports will be required. Each laboratory component is a non-compensatable course element. In order to pass the course students must attain a mark of at least 40% in each laboratory component (i.e. inorganic laboratory practical, organic laboratory practical, physical laboratory practical). This policy is in place so that students who proceed to the following year have an acceptable level of laboratory experience, taking into account both practical achievement and the safety of themselves, fellow students and staff.
 
Intermediate Inorganic Chemistry (10 credits, full year)
This module aims to survey the classical and new chemistry of the main group elements. To use group theory as a tool in the analysis of vibrational spectra in inorganic chemistry. To give a concise introduction to the organometallic chemistry of the transition metals. To use multinuclear NMR spectroscopy as a tool for the characterisation of molecules.
 
Principles in Analytical Chemistry (10 credits, Autumn semester)
 The module introduces the basic ideas of analytical chemistry, outlining general types of analytical problem, the main types of instrumentation used for separation and detection of analytes, and statistical treatment of analytical results. All principles will be illustrated by relevant recent examples from the literature.
 

 

20 compulsory credits from your chosen subpathway:

Organic subpathway

  • Intermediate Organic Spectroscopy and Stereochemistry (10 credits, Autumn semester)
The module provides both a theoretical description of modern spectroscopic techniques (NMR, IR, and mass spectrometry) for structural analysis of organic and biological molecules and practical applications of these techniques in problem solving. Aspects of the stereochemistry of bio-organic molecules are covered, including conformational analysis and stereocontrol in bio-organic reactions.
 
  • Intermediate Synthetic Organic Chemistry (10 credits, Spring semester)
The module is divided into two parts: (a) Functional group chemistry: synthetic transformations of alcohols, amines, carbonyls, and alkenes, and how these transformations are used to synthesise complex molecules such as natural products or pharmaceutical agents. (b) Synthesis: Introduction to retrosynthetic analysis and synthesis of organic molecules using a selection of pharmaceutical agents as examples. Formative feedback is given on the material in this module at the associated workshops. Summative feedback is provided after the exam by the module convenor.
 


Physical subpathway

  • Intermediate Spectroscopy and Quantum Chemistry (10 credits, Autumn semester)
  • Intermediate Physical Chemistry (10 credits, Spring semester)
 

 

Year Three

You will continue with the same two subjects studied in the second year, taking 50 credits in each. Alongside subject-specific study, you will undertake a 20-credit synoptic module which aims to tie together the subjects you are studying through an interdisciplinary group project.

Environmental Science


20 compulsory credits:

  • Natural Sciences Synoptic Module (20 credits, full year)


Compulsory with Biological Sciences

Environmental Biotechnology (10 credits, Spring semester)
This module provides training in environmental biotechnology, with particular emphasis on the interaction between microorganisms and the environment. The main topics covered will be wastewater treatment, bioremediation of organic and inorganic pollutants, microbes as indicators of risk factors in the environment, microbes in agriculture (biocontrol and biofertilisers) and the role of microorganisms in bioenergy production.
 


Compulsory with Chemistry

Environmental Pollutants (20 credits, Spring semester)
This module is concerned with the behaviour and effects of pollutants in terrestrial and aquatic environments and how their impacts can be ameliorated and managed. The focus is on both the scientific understanding of environmental pollutants and on the intervention strategies currently available. Topics covered include study of the common water and soil pollutants: heavy metal contamination of land, radionuclide behaviour in the environment, persistent organic contaminants and pesticides, nitrate pollution of groundwater, pollution of surface waters by agriculture, eutrophication of lakes, acidification of soils and freshwaters, biological monitoring of rivers, ecotoxicology and environmental epidemiology, quantitative risk assessment, land reclamation, including landfill sites.
 


Optional environmental science modules

A further 30 credits from the options below:

Arctic Ecology Field Course (10 credits, Autumn semester)
The course will focus on the function of arctic ecosystems. We will identify key terrestrial ecosystem drivers and processes in order to gain a broad understanding of arctic areas. During the field course, students will put ecological methodology into practice in projects that analyse landscape patterns and processes in different habitats. The course will also address climate change impacts on arctic ecosystems. The work will familiarise students with ecological methodology, experimental design, data collection and analysis, interpretation and presentation. Students are required to pay a contribution towards the cost of the field course.
 
Environmental Pollutants (20 credits, Spring semester)
This module is concerned with the behaviour and effects of pollutants in terrestrial and aquatic environments and how their impacts can be ameliorated and managed. The focus is on both the scientific understanding of environmental pollutants and on the intervention strategies currently available. Topics covered include study of the common water and soil pollutants: heavy metal contamination of land, radionuclide behaviour in the environment, persistent organic contaminants and pesticides, nitrate pollution of groundwater, pollution of surface waters by agriculture, eutrophication of lakes, acidification of soils and freshwaters, biological monitoring of rivers, ecotoxicology and environmental epidemiology, quantitative risk assessment, land reclamation, including landfill sites.
 
  • Environmental Biotechnology (10 credits, Spring semester)
This module provides training in environmental biotechnology, with particular emphasis on the interaction between microorganisms and the environment. The main topics covered will be wastewater treatment, bioremediation of organic and inorganic pollutants, microbes as indicators of risk factors in the environment, microbes in agriculture (biocontrol and biofertilisers) and the role of microorganisms in bioenergy production.
 
  • Environmental Pollution Field Course (10 credits, Autumn semester)
The field excursion will be of one week duration and will take place in September, immediately before semester 5. Students are required to pay a contribution towards the cost of the field course. The aim is to provide students with practical experience of a range of environmental pollution issues in a region of central Europe which historically has been one of the most polluted areas in the world. Specific issues covered during the excursion will be as follows:
  1. Soil acidification and forest decline/recovery.
  2. Contamination of soils and vegetation due to mining and air pollution.
  3. Biomonitoring using tree rings.
  4. Lignite mining and combustion, past and present.
  5. Reclamation of coal and uranium mines and contaminated land.
  6. Particulate and gaseous air pollution.
 
  • Computer Modelling in Science: Applications (20 credits, Autumn semester)
Modern biological and environmental science includes the study of complex systems and large data sets, including imaging data. This necessitates the use of computer models and analyses in order to understand these systems. This module contains an introduction to computer programming and modelling techniques that are used in the biological and environmental sciences. Specifically, it contains: (i) Development, simulation and analysis for models in space and time, using the Python language, with applications in the biological and environmental sciences; (ii) Analysis of long term behaviour of models in two or more dimensions; (iii) Methods for fitting models to experimental and environmental data; (iv) analysis of image data. The module will focus on relevant applications in environmental and biological science, e.g. chemical, radioactive and biological pollution, crop development and pathogens and microbiology. The module will use the Python programming language throughout and be assessed by a patchwork assessment consisting of write-ups of assignments from during the semester.
 
  • Geobiology (10 credits, Spring semester)
 

Biological Sciences


30 compulsory credits:

  • Natural Sciences Synoptic Module (20 credits, full year)
  • Molecular Biological Laboratory Studies (10 credits, Spring semester)
This is a mini project based practical module that not only aims to provide underlying principles of key techniques in molecular biology but also enables students to get hands-on experience in a wide range of molecular techniques.In addition, students will learn key skills in bioinformatics and will also be exposed to a few key analytical techniques.
 

30 compulsory credits from your chosen subpathway:


Molecular and Cellular Biology subpathway (option 1)

Advanced Biochemistry (20 credits, full year)
This module is divided into three parts: Firstly the application of genetic engineering to construct vectors that maximize the expression the expression of protein from cloned genes or cDNAs in heterologous systems will be discussed. Modern methods for the purification of recombinant proteins will be described. In the spring the module covers the life history of a protein from birth (synthesis) to death (apoptosis). The other major aspects that are involved include a discussion of protein folding, the cytoskeleton, protein and vesicle trafficking including endocytosis and protein degradation.
 
Gene Regulation (10 credits, Autumn semester)
Examines the mechanisms through which eukaryotic genes are expressed and regulated, with emphasis placed on recent research on transcriptional control in yeast and post-transcriptional control in eukaryotes. Studying this module will include having three hours of lectures per week.
 


Molecular and Cellular Biology subpathway (option 2)

Human Variation (10 credits, Autumn semester)
Examines genetic variation in humans, including variation at the DNA level, and the study of human population history using genetic methods. Around three hours per week will be spent within lectures studying this module.
 
Molecular and Cellular Neuroscience (10 credits, Autumn semester)
Considers ion channels at the molecular level, with topics including the structure and function of different ion channel groups and their modulation by drugs, pesticides and natural toxins. You will also consider the synthesis and transport of neurotransmitters and the formation and release of synaptic vesicles. This module involves one three hour session per week incorporating eight lectures and two practical sessions.
 
Molecular Evolution (10 credits, Spring semester)

During this module you will examine the ways in which DNA and protein sequences are used to investigate evolutionary relationships among organisms. You will study topics including the techniques of sequence comparison and the construction of evolutionary trees. You will spend three hours of lectures per week plus a total of two three-hour practicals in this module.

 


Organismal Biology subpathway

Evolutionary Ecology (10 credits, Autumn semester)
Considers current knowledge of, and research into, the ecological causes and evolutionary processes that govern natural selection, adaptation and microevolution in natural populations. You will examine three approaches to the study of evolutionary ecology: theoretical and optimality models; the comparative method; and direct measurement of natural selection in the wild. You will have two-to three hours of lectures each week in this module.
 
Population Genetics (10 credits, Autumn semester)
You will consider the history and practice of population genetics research, with a focus on a quantitative approach to the subject, with training in problem-solving skills. You will spend around two hours within lectures per week studying this module, plus a two-hour computer practical.
 
Molecular Evolution (10 credits, Spring semester)

During this module you will examine the ways in which DNA and protein sequences are used to investigate evolutionary relationships among organisms. You will study topics including the techniques of sequence comparison and the construction of evolutionary trees. You will spend three hours of lectures per week plus a total of two three-hour practicals in this module.

 


Genetics subpathway

Open to students from Molecular and Cellular Biology and Organismal Biology subpathways.

Human Variation (10 credits, Autumn semester)
Examines genetic variation in humans, including variation at the DNA level, and the study of human population history using genetic methods. Around three hours per week will be spent within lectures studying this module.
 
Population Genetics (10 credits, Autumn semester)
You will consider the history and practice of population genetics research, with a focus on a quantitative approach to the subject, with training in problem-solving skills. You will spend around two hours within lectures per week studying this module, plus a two-hour computer practical.
 
Molecular Evolution (10 credits, Spring semester)

During this module you will examine the ways in which DNA and protein sequences are used to investigate evolutionary relationships among organisms. You will study topics including the techniques of sequence comparison and the construction of evolutionary trees. You will spend three hours of lectures per week plus a total of two three-hour practicals in this module.

 

Additional biology modules

A further 10 credits from the options below:

Advanced Developmental Biology (10 credits, Autumn semester)
You will consider the molecular mechanisms underlying stem cell function during embryogenesis and adulthood. This will involve studies of regeneration and repair of tissues and pluripotency. You will have one two-hour lecture per week in this module. 
 
Aging, Sex and DNA Repair (10 credits, Spring semester)
Examine the molecular causes of the ageing and malignant transformations of somatic cells that are observed during a single lifespan, and gain an understanding of the necessity to maintain the genome intact from one generation to the next. Around three hours per week will be spent within lectures studying this module.
 
Cancer Biology (10 credits, Spring semester)
Examine a selection of acquired and inherited cancers, and develop an understanding of the role of the genes involved and how they can be analysed. To study for this module you will have a two- or three-hour lecture once per week.
 
 

Chemistry

30 compulsory credits:

  • Natural Sciences Synoptic Module (20 credits, full year)
  • Advanced Laboratory Techniques 'N' (10 credits, full year)
This course aims to teach advanced experimental techniques in chemistry. To provide experience in the recording, analysis and reporting of physical data. To put into practice the methods of accessing, assessing and critically appraising the chemical literature.
 


40 compulsory credits from your chosen subpathway:

Organic subpathway

  • Communicating Chemistry (10 credits, full year)
A classroom-based module for learning key skills including communication, presentation, team-working, active listening, time management and prioritisation. Increased transferable skills which will enhance employability and confidence. Provision of classroom experience if considering teaching as a potential career.
 
  • Bioinorganic and Metal Co-ordination Chemistry (10 credits, Autumn semester)
The aim of this module is to provide you with an understanding of coordination chemistry in the context of macrocyclic, supramolecular and bioinorganic chemistry and its applications in metal extraction and synthesis. You will gain an appreciation of the importance of metals in biological systems, and be able to explain the relationship between the structure of the active centres of metallo-proteins and enzymes and their biological functions. The module is assessed by a two-hour written exam.
 
  • Chemical Biology and Enzymes (10 credits, Autumn semester)
Discover the foundations of enzymological, chemical and molecular biological techniques needed to probe cellular processes and catalysis at the forefront of Chemical Biology research. By the end of the module you will understand the basic principles of protein expression, mutagenesis and purification, yeast two and three hybrid technology, protein NMR and Crystallography among other topics. There will be one and half hours of lectures a week.
 
  • Organometallic and Asymmetric Synthesis (10 credits, Autumn semester)
This module will introduce you to a range of reagents and synthetic methodology. You will learn how to describe how it is applied to the synthesis of organic target molecules. By the end of the module you will know how the use of protecting groups can be used to enable complex molecule synthesis and how modern palladium-mediated cross-coupling reactions can be used to synthesise useful organic molecules. Your problem-solving and written communication skills will be developed.
 
  • Protein Folding and Biospectroscopy (10 credits, Autumn semester)
This module will develop an understanding of protein structure, stability, design and methods of structural analysis. In addition you will understand the protein folding problem and experimental approaches to the analysis of protein folding kinetics and the application of site-directed mutagenesis. You will also be expected to develop a number of spectroscopic experimental techniques to probe protein structures. There will be two hours of lectures a week.
 
  • Catalysis (10 credits, Spring semester)
This module aims to provide a framework for understanding the action of heterogeneous catalysts in terms of adsorption/desorption processes and for understanding catalyst promotion in terms of chemical and structural phenomenon and also describes a wide variety of homogeneous catalytic processes based on organo-transition metal chemistry.
 
  • Topics in Inorganic Chemistry (10 credits, Spring semester)
This module covers inorganic mechanisms and the overarching fundamental principles of greener and sustainable chemistry as applied to processes, inorganic reaction mechanisms, and discussion on the theme of greener and sustainable chemistry
 
Pericyclic Chemistry and Reactive Intermediates (10 credits, Spring semester)
Use of frontier molecular orbital analysis to explain and predict stereochemical and regiochemical outcomes of pericyclic reactions (Woodward-Hoffmann rules etc). Examples will be drawn from Diels-Alder reactions, cycloadditions [4+2] and [2+2], [3,3]-sigmatropic rearrangements (eg Claisen and Cope), [2,3]-sigmatropic rearrangements (eg Wittig and Mislow-Evans). Generation and use of reactive intermediates in synthesis (ie radicals, carbenes, nitrenes).
 


Physical subpathway

  • Communicating Chemistry (10 credits, full year)
A classroom-based module for learning key skills including communication, presentation, team-working, active listening, time management and prioritisation. Increased transferable skills which will enhance employability and confidence. Provision of classroom experience if considering teaching as a potential career.
 
  • Bioinorganic and Metal Co-ordination Chemistry (10 credits, Autumn semester)
The aim of this module is to provide you with an understanding of coordination chemistry in the context of macrocyclic, supramolecular and bioinorganic chemistry and its applications in metal extraction and synthesis. You will gain an appreciation of the importance of metals in biological systems, and be able to explain the relationship between the structure of the active centres of metallo-proteins and enzymes and their biological functions. The module is assessed by a two-hour written exam.
 
  • Chemical Bonding and Reactivity (10 credits, Autumn semester)
To provide a fundamental understanding of molecular structure and of the requirements for reactivity. To introduce modern electronic structure theory and demonstrate how it can be applied to determine properties such as molecular structure, spectroscopy and reactivity.
 
  • Protein Folding and Biospectroscopy (10 credits, Autumn semester)
This module will develop an understanding of protein structure, stability, design and methods of structural analysis. In addition you will understand the protein folding problem and experimental approaches to the analysis of protein folding kinetics and the application of site-directed mutagenesis. You will also be expected to develop a number of spectroscopic experimental techniques to probe protein structures. There will be two hours of lectures a week.
 
  • Catalysis (10 credits, Spring semester)
This module aims to provide a framework for understanding the action of heterogeneous catalysts in terms of adsorption/desorption processes and for understanding catalyst promotion in terms of chemical and structural phenomenon and also describes a wide variety of homogeneous catalytic processes based on organo-transition metal chemistry.
 
  • Lasers in Chemistry (10 credits, Spring semester)
A general introduction to lasers, including laser radiation and its properties will be given, leading to why lasers have such widespread uses in Chemistry. The bulk of the module is devoted to selected applications, which will include some of: atmospheric measurements; combustion; photochemistry and synthesis; chemical kinetics; spectroscopic studies of isolated molecules (stable and reactive); studies of van der Waals complexes; studies of small metal clusters and nanoparticles; time-resolved studies.
 
Solids, Interfaces and Surfaces (10 credits, Spring semester)
This course aims to teach the relationship between structure and properties of solids, structure of Solids and characterisation. It aims to teach a general introduction to Interfaces and Surfaces.
 
Topics in Inorganic Chemistry (10 credits, Spring semester)
This module covers inorganic mechanisms and the overarching fundamental principles of greener and sustainable chemistry as applied to processes, inorganic reaction mechanisms, and discussion on the theme of greener and sustainable chemistry
 
 

 

Year Four (MSci students only)

You will choose one of your third-year subjects to focus on in the fourth year, spending half your time working on an independent research project aiming to develop the skills needed to pursue a career in research. Alongside the project you take taught modules in your main subject and if you wish to maintain some breadth you can also take options from your other third year subject.

Environmental Science


100 compulsory credits:

  • Environmental Science Research Project (60 credits, full year)
Writing and Reviewing Research Proposals (20 credits, full year)
The overall aim is to consider, practice, write and assess research proposals. In the real world, one may have to communicate to experts within your discipline or to non-specialist professionals. A subsidiary aim is to give students information and teach skills, which will help them in coursework assignments. A third aim is to give students the opportunity to study a topic, which may not otherwise be formally covered, and to communicate that topic to their peers.
 
  • Project Management (20 credits, full year)
Project management skills are a highly transferable skill directly relevant to employment sectors. The module will cover the fundamentals of project management, including project lifecycles, leadership in project management, managing risk in projects, analysis of project successes and failures and project management software. Students will produce a documented project management outline tailored to their research project to identify the key constraints, bottlenecks and milestones. This will be supplemented by the production of appropriate project management visualisation diagram, ie a Gantt or PERT chart. They will also present an interim verbal report to their supervisors and the module convenor to rehearse such reporting skills.
 
  • Statistics and Experimental Design for Bioscientists (10 credits, Autumn semester)
Principles of experimentation in crop science, basic statistical principles, experimental design, hypothesis testing, sources of error, analysis of variance, regression techniques, presentation of data, use of Genstat for data analysis. There are two routes through the module, one focusing on crop improvement and one focusing on more general issues.
 


Optional environmental science modules

Minimum of 0 credits, maximum of 10 credits from the options below:

  • Syndicate Exercise (10 credits, Spring semester)
This module covers the preparation of a group presentation and individual report on an environmental subject.
 
 

Biological Sciences


100 compulsory credits:

Life Sciences Project (60 credits, full year)
The project is a year-long module. Preparatory work (familiarisation with laboratory/field safety protocols etc.) will occur in autumn, with the bulk of practical work in spring. The topic of the project will be chosen from a list of suggestions relevant to the degree subject, and will be finalised after consultation with a member of staff, who will act as a supervisor. The project involves an extensive piece of detailed research on the topic chosen after discussion with the supervisor. The practical component will involve collection of data from a laboratory or field investigation and appropriate analysis. The findings will be interpreted in the context of previous work, and written-up in a clear and concise final report in the form of a research paper manuscript or end-of-grant report. The main findings will also be delivered in an assessed oral presentation and discussed with two assessors in a viva voce.
 
Research Planning and Preparation (20 credits, full year)

This is a year-long module, but with most of the work being complete by the end of January. The module focuses on the preparing students to engage in substantial independent research in Life Sciences, and is supported by lecture content in Research Presentation Skills (C14705). Students choose a research topic from a list provided the previous academic year, and are allocated an individual research supervisor accordingly. In regular meetings, student and supervisor discuss relevant research literature and design a practical research project addressing a specific hypothesis. Assessment is via a substantial research proposal.

 
Research Presentation Skills (20 credits, full year)
The module aims to provide students with a range of presentation and IT skills that are essential for modern biological researchers. The workshop content will provide a conceptual framework, while journal clubs and coursework will deliver the hands-on experience required to develop appropriate practical skills.
 

 
Optional biology modules

Up to a further 20 credits from the options below:

  • Cutting-edge Research Technologies and Ideas in Molecular Biology (10 credits, Autumn semester)
This module will bring you up to date with the latest technological developments in molecular biology that you are unlikely to have encountered in detail in your first three years. We also discuss and explore how new technologies with broad implications come into existence and follow the process of establishment, acceptance and dissemination through the scientific community. You will have a three hour workshop once per week for this module.
 
  • Advanced Experimental Design and Analysis (10 credits, Autumn semester)
This is an advanced level biological statistics module which builds on basic undergraduate training. Lectures discuss concepts in experimental design, biological probability, generalised linear modelling and multivariate statistics. Practical sessions build on this conceptual outline, giving you hands-on experience of problem solving and analytical software, and some basic programming skills. You will spend three to four hours within lectures and workshops when studying this module.
 
  • Process and Practice in Science (10 credits, Autumn semester)
A consideration of science ‘as a process’, with brief introductions to the history, philosophy and sociological norms of science. You will cover aspects of the scientific literature and scientific communication, peer review, 'metrics’, including citation analysis, journal impact factors, and the 'h' and other indices of measuring scientists' performances. You will also cover ethics in science and the changing relationship between scientists, government and the public. You will have a three hour lecture once per week during this module.
 
  • Current Trends in Neuroscience (10 credits, Autumn semester)
This module will be concerned with an appreciation of current and future directions of research in neuroscience. Current topics will be selected as appropriate from scientific journals (eg Nature, Science, Brain Research, Journal of Neuroscience ) and/or review journals (eg Trends in Neuroscience, Trends in Pharmacological Sciences, Annual Review series).
 
 

Chemistry


60 compulsory credits:

  • Chemistry Research Project (60 credits, full year)
This module will give students the opportunity to undertake a research project in Chemistry. A wide range of projects will be available and students will be offered a selection of research areas. All projects will require a review of relevant published work and the planning and execution of a research topic under the guidance of two supervisors. Students will present their findings orally and in a written report. 
 

 

Minimum of 20 credits, maximum of 60 credits from the options below:

Enterprise for Chemists (10 credits, full year)
Students will learn about the factors that lead to successful innovation, including evaluation and management of an idea/concept. In addition, students will consider the factors required to extract the value from a product/concept (e.g. market awareness) and the potential routes to market available from both an academic and industrial viewpoint.
 
 Advanced Physical Chemistry 1 (10 credits, Autumn semester)
The module covers advanced topics of current importance in Physical Chemistry. (1) Intermolecular Forces. Relevance of intermolecular forces. Calculating and measuring intermolecular forces. Computer modelling and simulations of condensed phases. Molecular properties and the multipole expansion. Perturbation theory of intermolecular forces. Monte Carlo simulations and calculation of thermodynamic properties. (2) Chemical Sensors. Principles of chemical sensing. Operating principles of electrochemical sensors, including ion-selective electrodes and amperometric sensors. Potentiometric and amperometric enzyme electrodes. DNA-based sensors. Piezoelectric sensors and biosensors. Immunological sensors and enzyme-linked immunosorbent assays.
 
  • Contemporary Organic Synthesis (10 credits, Autumn semester)

Explore the synthesis of a variety of natural (and unnatural) compounds of relevance to biology and medicine, with reference to the goals and achievements of contemporary organic synthesis through a range of case studies. There is an emphasis on the use of modern synthetic methodology to address problems such as chemoselectivity, regiocontrol, stereoselectivity, atom economy and sustainability.

You will also study the application of new methodology for the rapid, efficient and highly selective construction of a range of target compounds - particularly those that display significant biological activity. There will also be an opportunity to address how a greater understanding of mechanism is important in modern organic chemistry. This module is assessed by a two hour exam.

 
Contemporary Physical Chemistry (10 credits, Autumn semester
 

Applications will be introduced that range from condensed matter through to gas phase, but novel “states” of matter such as ultracold molecules in traps and liquid He nanodroplets, microsolvated clusters, and low dimensional carbon structures will also be covered. The dynamics of chemical processes, including non-adiabatic interactions will be discussed, and the capability of modern light sources allowing for the study of time-resolved measurements on chemically relevant timescales ranging from pico- to attoseconds will be explained and illustrated. Methods for the state-selective preparation and detection of molecular systems will be discussed. The principles by which extended systems can be designed to have properties allowing use in novel sensors and devices will be introduced. A wide range of computational techniques will be covered which underpin the modelling of cutting edge scientific applications such as gas capture and storage at the nanometer scale and novel nanomaterials.

 
Inorganic and Materials Chemistry A (10 credits, Autumn semester)
This course aims to give knowledge and understanding of (i) the structure, bonding and physicochemical properties of carbon nanostructures; (ii) the key technological applications of graphene, carbon nanotubes and fullerenes; (iii) the historical and the most modern approaches to advanced polymeric materials manufacture; (iv) the most important structure property relationships of polymeric materials and how these can be controlled, measured and exploited.
 
  • Inorganic and Materials Chemistry B (10 credits, Autumn semester)

This module builds on the previous years' modules on both transition metal chemistry and structural chemistry and focuses on Inorganic Photochemistry and Crystal Structure Determination. Photochemistry topics covered include Electron transfer pathways; dynamics and energies; biological systems; mixed valance compounds; Principles of molecular and supramolecular photochemistry; Applications of inorganic photochemistry; probes for DNA, ion sensors, artificial photosynthesis, photocatalysis, photodynamic therapy of cancer treatment. Crystal Structure Determination topics covered include an Introduction and Overview; a survey of key background concepts; sample preparation and evaluation; data acquisition and processing; structure solution and refinement; interpretation and analysis of results; case studies of routine and challenging structural problems; related techniques; sources and detectors; current practice and future developments.

 
Medicines from Nature (10 credits, Autumn semester)
This course aims to give an overview of the history of natural products and their importance to the discovery of medicines. To describe the relationship of natural products and how they are synthesised in nature to medicines in the following areas: non-steroid anti-inflammatory agents, steroids, polyketides and terpenes, vitamins, cannabinoids, anti-cancer agents, alkaloids and neurotransmitters and anti-biotics.To delineate the principles of process chemistry as applied to the pharmaceutical industry. To consider six main aspects of process chemistry: Safety, Environmental; Legal; Economics; Control; Throughput. To consider how these aspects can affect the viability of a synthesis and lead to the development of alternatives that are safer, have lower environmental impact, and are more efficient and cost-effective.
 
  • Advanced Physical Chemistry 2 (10 credits, Spring semester)
The module provides the student with the opportunity to study the topics of Astrophysical Chemistry and Quantum Mechanics and Spectroscopy to a more advanced level building on the Chemistry covered in the core modules.
 
  • Advanced Biocatalysis, Biosynthesis and Chemical Biology (10 credits, Spring semester)
Advanced Chemical Biology: To introduce concepts of chemical genetics and including activity-based protein profiling, non-natural amino acid incorporation, bio-orthogonal reactivity and the use of bump-and-hole strategies, applied to various challenges such as finding kinase/target pairs. Biocatalysis: To introduce enzyme engineering and the synthetic utility of designer biocatalysts, especially highlighting chemo-enzymatic approaches toward chiral commodity molecules (e.g. pharmaceuticals) and their precursors. Biosynthesis: To introduce the biosynthetic pathways and enzyme catalysed reactions leading natural products polyketides, terpenes, fatty acids and non-ribosomal peptides.
 
  • Nucleic Acids and Bio-organic Mechanism (10 credits, Spring semester)
During this module you will learn to understand in depth the structure, chemistry and molecular recognition of nucleic acids and their reactivity towards mutagens, carcinogens and ionising radiation and anti-tumour drugs. You will appreciate the plasticity and dynamics of the DNA duple helix through base motions that underpin its function. The bacterial replisome will be used as the prime example to highlight the problems associated with DNA replication and the significance of telomeres will be discussed. Alongside this you will develop an understanding of the chemical reactivity of coenzymes and how these add significantly to the functionality of the 20 amino acids found in proteins. 
 
  • Self-assembly and Bottom-up Approaches to Nanostructure Fabrication (10 credits, Spring semester)
 

 

The following is a sample of the typical modules that we offer as at the date of publication but is not intended to be construed and/or relied upon as a definitive list of the modules that will be available in any given year. Due to the passage of time between commencement of the course and subsequent years of the course, modules may change due to developments in the curriculum and the module information in this prospectus is provided for indicative purposes only.

 

Natural Sciences

School of Chemistry, University of Nottingham
University Park
NG7 2RD

Tel: +44 (0) 115 823 2376
Fax: +44 (0) 115 951 3555
Email: naturalsciences@nottingham.ac.uk