RLO: Lock and Key Hypothesis

 

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You can see that most drugs are designed to act on molecules that already act as targets for other substances within the body. In fact, the drug mimics the endogenous molecule in order to bind to its target and either stimulate or block its action. See if you can complete the following table by matching the endogenous substance with its target and then matching the drug that mimics its actions. Look for structural similarities. Press the start button to begin.