| Array printing |
Array printing using pin and piezo instruments |
Advanced Materials and Healthcare Technologies |
Morgan Alexander |
| Atomic force microscopy |
Atomic force microscopy (including environmental control options) |
Advanced Materails and Healthcare Technologies |
Clive Roberts |
| Drug Discovery |
Drug discovery and medicinal chemistry in the areas of oncology, cardiovascular disease, infection & immunity, respiratory disease, inflammation, neurodegenerative disease |
Biomolecular Science and Medicinal Chemistry |
Peter Fischer |
| Medicinal Chemistry |
Drug discovery and medicinal chemistry in the areas of oncology, cardiovascular disease, infection & immunity, respiratory disease, inflammation, neurodegenerative disease |
Biomolecular Science and Medicinal Chemistry |
Peter Fischer |
| High throughput compound screening |
High throughput compound screening: fully automated state-of-the-art facility for a managed compound collection (initially >100k diverse drug-like small molecules) currently being established |
Biomolecular Science and Medicinal Chemistry |
Peter Fischer |
| Computational Methods |
High performance computational methods for molecular modelling, nanomedicine and drug design |
Biomolecular Science and Medicinal Chemistry |
Charles Laughton |
| High performance computing |
Computational methods for molecular modelling, nanomedicine and drug design |
Biomolecular Science and Medicinal Chemistry |
Charles Laughton |
| Molecular modelling |
Computational methods for molecular modelling, nanomedicine and drug design |
Biomolecular Science and Medicinal Chemistry |
Charles Laughton |
| Structure-based ligand design |
Active Site Pressurisation (ASP): a new structure-based ligand design that takes into account target protein |
Biomolecular Science and Medicinal Chemistry |
Charles Laughton |
| Drug design |
Computational methods for molecular modelling, nanomedicine and drug design |
Biomolecular Science and Medicinal Chemistry |
Charles Laughton |
| Protein-protein interactions |
Characterisation of protein-protein and protein-ligand interactions. LXXLL and related motifs. |
Biomolecular Science and Medicinal Chemistry |
Lodewijk Dekker, Stephanie Allen, David Heery |
| Protein-ligand interactions |
Characterisation of protein-protein and protein-ligand interactions. LXXLL and related motifs. |
Biomolecular Science and Medicinal Chemistry |
Lodewijk Dekker, Stephanie Allen, David Heery |
| Enzymes |
Mechanism of enzymatic reactions, using X-ray crystallographyMechanism of enzymatic reactions, using X-ray crystallography |
Biomolecular Science and Medicinal Chemistry |
Jonas Emsley |
| Fluorescent ligand design |
Fluorescent ligand design |
Biomolecular Science and Medicinal Chemistry |
Barrie Kellam |
| Peptides |
Chemistry of peptides and peptidomimetics |
Biomolecular Science and Medicinal Chemistry |
Weng Chan |
| Chemical biology |
Chemical biology in the areas of infection,oncology and neurodegenerative disease |
Biomolecular Science and Medicinal Chemistry |
Weng Chan |
| Drug discovery |
Drug discovery in the areas of infection,oncology and neurodegenerative disease |
Biomolecular Science and Medicinal Chemistry |
Weng Chan |
| Medicinal chemistry |
Medicinal chemistry in the areas of infection,oncology and neurodegenerative disease |
Biomolecular Science and Medicinal Chemistry |
Weng Chan |
| Peptidomimetics |
Chemistry of peptides and peptidomimetics |
Biomolecular Science and Medicinal Chemistry |
Weng Chan |
| Protein Structure |
Protein structure determination by X-ray crystallography |
Biomolecular Science and Medicinal Chemistry |
Jonas Emsley |
| X-ray crystallography |
Protein structure determination by X-ray crystallography |
Biomolecular Science and Medicinal Chemistry |
Jonas Emsley |
| High throughput crystallisation robotics |
High throughput crystallisation robotics for X-ray diffraction studies |
Biomolecular Science and Medicinal Chemistry |
Jonas Emsley |
| Fluorescent assay technology |
Fluorescent assay technology |
Biomolecular Science and Medicinal Chemistry |
Barrie Kellam |
| NMR spectroscopy |
NMR spectroscopy |
Biomolecular Science and Medicinal Chemistry |
Lee Hibbett |
| Mass spectrometry (including LC-MS-MS) |
Mass spectrometry (including LC-MS-MS) |
Biomolecular Science and Medicinal Chemistry |
Lee Hibbett |
| High pressure liquid chromatography |
High pressure liquid chromatography |
Biomolecular Science and Medicinal Chemistry |
Lee Hibbett |
| Biomedical materials |
Biomaterials and biosurfaces for biomedical applications |
Advanced Materials and Healthcare Technologies |
Morgan Alexander |
| Surface chemical characterisation |
Surface chemical characterisation |
Advanced Materials and Healthcare Technologies |
Morgan Alexander |
| Surface chemical modification |
Surface chemical characterisation |
Advanced Materials and Healthcare Technologies |
Morgan Alexander |
| Nanoscale characterisation |
Nanoscale characterisation and imaging |
Advanced Materials and Healthcare Technologies |
Clive Roberts |
| Nanoscale imaging |
Nanoscale characterisation and imaging |
Advanced Materials and Healthcare Technologies |
Clive Roberts |
| Crystallisation |
Crystallisation |
Advanced Materials and Healthcare Technologies |
Martyn Davies |
| Protein folding & unfolding |
Protein folding & unfolding |
Molecular Therapeutics and Formulation |
Phil Williams |
| Polymorphs |
Polymorph screening and materials characterisation |
Molecular Therapeutics and Formulation |
Jonathan Burley |
| Fluorescence sensing |
Fluorescence sensing |
Advanced Materials and Healthcare Technologies |
Jonathan Aylott |
| Chemical sensors and biosensors |
Chemical sensors and biosensors |
Advanced Materials and Healthcare Technologies |
Jonathan Aylott |
| Atomic force microscopy |
Atomic force microscopy (including environmental control options) |
Advanced Materials and Healthcare Technologies |
Clive Roberts |
| Scanning thermal microscopy |
Scanning thermal microscopy. Differential scanning calorimetry and nanothermal analysis. |
Advanced Materials and Healthcare Technologies |
Clive Roberts |
| Differential scanning calorimetry |
Scanning thermal microscopy. Differential scanning calorimetry and nanothermal analysis. |
Advanced Materials and Healthcare Technologies |
Clive Roberts |
| Nanothermal analysis |
Scanning thermal microscopy. Differential scanning calorimetry and nanothermal analysis. |
Advanced Materials and Healthcare Technologies |
Clive Roberts |
| Optical tweezers |
Optical tweezers |
Advanced Materials and Healthcare Technologies |
Clive Roberts |
| Surface plasmon resonance |
Surface plasmon resonance |
Advanced Materials and Healthcare Technologies |
Clive Roberts |
| X-ray powder diffraction |
X-ray powder diffraction |
Advanced Materials and Healthcare Technologies |
Clive Roberts |
| Confocal Raman spectroscopy |
Confocal Raman spectroscopy, including variable temperature and spatial mapping |
Molecular Therapeutics and Formulation |
Phil Williams, Jonathan Burley |
| Biopharmaceuticals |
Biopharmaceuticals design, characterisation and formulation |
Molecular Therapeutics and Formulation |
Stephanie Allen |
| UV/Vis spectroscopy |
UV/vis and IR spectroscopy, including PM IRRAS and ATR. |
Advanced Materials and Healthcare Technologies |
Morgan Alexander |
| IR spectroscopy |
UV/vis and IR spectroscopy, including PM IRRAS and ATR. |
Molecular Therapeutics and Formulation |
Jonathan Burley |
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| ToF-SIMS |
ToF-SIMS, including spatial mapping & depth profiling. X-ray photoelectron spectroscopy. |
Advanced Materials and Healthcare Technologies |
Morgan Alexander |
| X-ray photoelectron spectroscopy |
ToF-SIMS, including spatial mapping & depth profiling. X-ray photoelectron spectroscopy. |
Advanced Materials and Healthcare Technologies |
Morgan Alexander |
| Scanning Electron Microscope/Cryo-SEM |
Comprehensive Scanning Electron Microscope (SEM) facility/service. There is also Cryo-SEM available for freeze fracturing wet samples. |
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| Microparticle synthesis |
Micro & Nanoparticle synthesis and particle size analysis - including dynamic light scattering, laser particle sizing, zetapotential, disc centrifuge, Nanosight |
Molecular Therapeutics and Formulation |
Snow Stolnik, Clive Roberts |
| Microparticle sizing and characterisation |
Micro & Nanoparticle synthesis and particle size analysis - including dynamic light scattering, laser particle sizing, zetapotential, disc centrifuge, Nanosight |
Molecular Therapeutics and Formulation |
Snow Stolnik , Clive Roberts |
| Nanoparticle synthesis |
Micro & Nanoparticle synthesis and particle size analysis - including dynamic light scattering, laser particle sizing, zetapotential, disc centrifuge, Nanosight |
Molecular Therapeutics and Formulation |
Snow Stolnik, Clive Roberts |
| Nanoparticle sizing and characterisation |
Micro & Nanoparticle synthesis and particle size analysis - including dynamic light scattering, laser particle sizing, zetapotential, disc centrifuge, Nanosight |
Molecular Therapeutics and Formulation |
Snow Stolnik, Clive Roberts |
| Nanoscale drug delivery systems |
Nanoscale and colloidal drug delivery systems |
Molecular Therapeutics and Formulation |
Martin Garnett |
| Colloidal delivery systems |
Nanoscale and colloidal drug delivery systems |
Molecular Therapeutics and Formulation |
Cynthia Bosquillon |
| Protein formulation |
Small molecule, protein and nucleic acid formulation including controlled release and extended half-life |
Molecular Therapeutics and Formulation |
Martin Garnett |
| Nucleic acid formulation |
Small molecule, protein and nucleic acid formulation including controlled release and extended half-life |
Molecular Therapeutics and Formulation |
Martin Garnett |
| Mucosal Drug Delivery |
Oral, mucosal and pulmonary drug delivery |
Molecular Therapeutics and Formulation |
Snow Stolnik |
| Pulmonary drug delivery |
Oral, mucosal and pulmonary drug delivery |
Molecular Therapeutics and Formulation |
Cynthia Bosquillon |
| Lung absorption models |
In vitro drug permeability studies, models of lung epithelia |
Molecular Therapeutics and Formulation |
Snow Stolnik |
| In vitro drug permeability studies |
In vitro drug permeability studies, models of lung epithelia |
Molecular Therapeutics and Formulation |
Snow Stolnik |
| Isolated perfused rat lungs |
Isolated perfused rat lungs |
Molecular Therapeutics and Formulation |
Cynthia Bosquillon |
| Drug transporters in the lung |
Drug transporters in the lung |
Molecular Therapeutics and Formulation |
Cynthia Bosquillon |
| Cell delivery systems |
Cellular and mitochondrial delivery vectors |
Molecular Therapeutics and Formulation |
Cameron Alexander |
| Stimuli-responsive polymers |
Stimuli-responsive polymers |
Molecular Therapeutics and Formulation |
Cameron Alexander |
| Polymer synthesis |
Polymer design and biomaterials synthesis |
Molecular Therapeutics and Formulation |
Cameron Alexander |
| Biomaterials synthesis |
Polymer design and biomaterials synthesis |
Regenerative Medicine and Cellular Therapies |
Kevin Shakesheff |
| Scaffolds for regenerative medicine |
Scaffolds for regenerative medicine |
Regenerative Medicine and Cellular Therapies |
Kevin Shakesheff |
| Stem cell science |
Stem cell science including adult and embryonic stem cells |
Regenerative Medicine and Cellular Therapies |
Lee Buttery |
| Fluorescence spectroscopy |
Light microscopy including epifluorescence and confocal. Fluorescence spectroscopy. |
Regenerative Medicine and Cellular Therapies |
Felicity Rose |
| 3D imaging of solids |
Microcomputed tomography for 3D imaging of solids and porous materials |
Regenerative Medicine and Cellular Therapies |
Kevin Shakesheff |
| Microcomputed tomography |
Microcomputed tomography for 3D imaging of solids and porous materials |
Regenerative Medicine and Cellular Therapies |
Kevin Shakesheff |
| Thermal properties of polymers |
Thermal and mechanical properties of polymers |
Regenerative Medicine and Cellular Therapies |
Kevin Shakesheff |
| Mechanical Properties of polymers |
Thermal and mechanical properties of polymers |
Regenerative Medicine and Cellular Therapies |
Kevin Shakesheff |
| Materials characterisation |
Materials characterisation (NMR, size exclusion chromatography) |
Molecular Therapeutics and Formulation |
Cameron Alexander |
| Supercritical fluid technologies |
Supercritical fluid technologies |
Regenerative Medicine and Cellular Therapies |
Kevin Shakesheff |
| In vitro models |
In vitro models of bone, liver and other tissues |
Regenerative Medicine and Cellular Therapies |
Lee Buttery |
| Stimuli-responsive polymers |
Stimuli-responsive polymers |
Molecular Therapeutics and Formulation |
Cameron Alexander, Giuseppe Mantovani |
| Polymer synthesis |
Polymer design and biomaterials synthesis |
Molecular Therapeutics and Formulation |
Cameron Alexander, Giuseppe Mantovani |
| Materials characterisation |
Materials characterisation (NMR, size exclusion chromatography) |
Molecular Therapeutics and Formulation |
Cameron Alexander, Giuseppe Mantovani |
| Glycomaterials synthesis |
Glycopolymers design and protein glycoconjugates synthesis |
Molecular Therapeutics and Formulation |
Giuseppe Mantovani |
| Protein-polymer biohybrid materials |
Site-specific protein conjugation |
Molecular Therapeutics and Formulation |
Giuseppe Mantovani |
| LC-MS |
LC-MS analysis (qualitative or qualitative) of low (<1200) biological molecules using electrospray or APCI ionisation modes with either accurate mass/high resolution, MSn or targeted (MRM) MS detection |
Advanced Materials and Healthcare Technologies, Centre of Analytical Bioscience
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Dave Barrett, Dong-Hyun Kim, Catherine Ortori
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| Ambient mass spectrometry |
Ambient analysis of biologically relevant surfaces and tissues by liquid extraction surface analysis (LESA) and desorption electrospray ionisation (DESI)-mass spectrometry |
Advanced Materials and Healthcare Technologies, Centre of Analytical Bioscience
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Dave Barrett, Dong-Hyun Kim, Catherine Ortori
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| Transcription factors |
Transcription factors – nuclear receptors, p53, AML1, IRFs. |
Biomolecular Science and Medicinal Chemistry
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David Heery |
| Transcription cofactors. |
Transcription cofactors. |
Biomolecular Science and Medicinal Chemistry |
David Heery |
| Proteomics and enzymology |
Proteomics and enzymology |
Regenerative Medicine and Cellular Therapies |
David Pritchard |
| Post-translational modifications – SUMOylation. |
Post-translational modifications – SUMOylation. SUMOylation assays. |
Biomolecular Science and Medicinal Chemistry |
David Heery |
| Chromatin modification |
Chromatin modification |
Biomolecular Science and Medicinal Chemistry |
David Heery |
| Histone acetyltransferases |
Histone acetyltransferases. HAT assays and chemical inhibitor screens. |
Biomolecular Science and Medicinal Chemistry |
David Heery |
| Immunology |
Immunology |
Regenerative Medicine and Cellular Therapies |
David Pritchard |
| Allergology |
Allergology |
Regenerative Medicine and Cellular Therapies |
David Pritchard |
| Parasites as therapy |
Parasite culture and clinical trial support |
Regenerative Medicine and Cellular Therapies |
David Pritchard |
| cDNA library construction |
Yeast two hybrid. Protein expression, purification and analysis. cDNA library construction. |
Regenerative Medicine and Cellular Therapies |
David Pritchard |
| Protein expression |
Yeast two hybrid. Protein expression, purification and analysis. cDNA library construction. |
Regenerative Medicine and Cellular Therapies |
David Pritchard |
| Protein Purification |
Yeast two hybrid. Protein expression, purification and analysis. cDNA library construction. |
Regenerative Medicine and Cellular Therapies |
David Pritchard |
| Protein Analysis |
Yeast two hybrid. Protein expression, purification and analysis. cDNA library construction. |
Regenerative Medicine and Cellular Therapies |
David Pritchard |
| Flow Cytometry |
Flow cytometry/FACS analysis |
Regenerative Medicine and Cellular Therapies |
David Pritchard |
| Stem cell transformation assays |
Haematopoietic stem cell transformation assays |
Regenerative Medicine and Cellular Therapies |
Lee Buttery |
| Immune cell culture |
Complex immune cell separation and culture (Treg, dendritic cells) |
Regenerative Medicine and Cellular Therapies |
David Pritchard |
| Immune cell separation |
Complex immune cell separation and culture (Treg, dendritic cells) |
Regenerative Medicine and Cellular Therapies |
David Pritchard |
| Allergy models |
Wound healing and allergy models |
Regenerative Medicine and Cellular Therapies |
David Pritchard |
| Wound healing models |
Wound healing and allergy models |
Regenerative Medicine and Cellular Therapies |
David Pritchard |
| Antibody assays |
Antibody & cytokine/chemokine assays |
Regenerative Medicine and Cellular Therapies |
David Pritchard |
| Cytokine/chemokine assays |
Antibody & cytokine/chemokine assays |
Regenerative Medicine and Cellular Therapies |
David Pritchard |
| E-Health |
E-Health |
Pharmacy Practice & Policy |
Claire Anderson |
| Role of the pharmacist |
Role of the pharmacist in improving the health of the public |
Pharmacy Practice & Policy |
Claire Anderson |
| Non-medical prescribing |
Non-medical prescribing |
Pharmacy Practice & Policy |
Claire Anderson |
| Pharmacy law and ethics |
Pharmacy law and ethics |
Pharmacy Practice & Policy |
Claire Anderson |
| Medicines adherence |
Medicines adherence |
Pharmacy Practice & Policy |
Claire Anderson |
| Pharmacy education |
Pharmacy education |
Pharmacy Practice & Policy |
Claire Anderson |
| Medicines use and safety |
Medicines use and safety |
Pharmacy Practice & Policy |
Claire Anderson |
| Qualitative Research |
Qualitative research (in-depth interviews & focus groups, observation, case studies) |
Pharmacy Practice & Policy |
Claire Anderson |
| Systematic literature reviews |
Systematic literature reviews |
Pharmacy Practice & Policy |
Claire Anderson |
| Primary care database manipulation |
Primary care database manipulation |
Pharmacy Practice & Policy |
Matt Boyd |
| Survey design and analysis |
Survey design and analysis |
Pharmacy Practice & Policy |
Claire Anderson |