Dr. Kong obtained her Bsc (Hons) in Biomedical Sciences from National University of Malaysia (UKM) and completed her PhD in Biochemistry from the same university. She worked as a post-doctoral research fellow in UKM before being appointed as Assistant Professor in University of Nottingham Malaysia in August 2016. She has also completed her Postgraduate Certificate in Higher Education in June 2018.
I am currently involved in teaching the following modules;-
BIOM1001 Scientific Basis of Medicine
BIOM1002 Core Skills in Biomedical Sciences
LIFE1051 Fundamentals of Neuroscience (Module convener)
BIOS1033 Microbial Physiology (Practical)
LIFE2029 Neurobiology of Diseases
BIOS2060 Microbial Mechanisms of Food Borne Disease (Practical)
LIFE3052 Concept of Pharmacogenetics
LIFE3054 Biochemistry of Diseases (Module convener)
LIFE3053 Biomedical Science Final Year Project
My overarching research interests revolve around the identification of novel anti-infective strategies to tackle antimicrobial drug resistance. My research focuses mainly on the discovery of… read more
CHIN CY, HARA Y, GHAZALI AK, YAP SJ, KONG C, WONG YC, ROZALI N, KOH SF, HOH CC, PUTHUCHEARY SD and NATHAN S, 2015. Global transcriptional analysis of Burkholderia pseudomallei high and low biofilm producers reveals insights into biofilm production and virulence. BMC genomics. 16, 471
My overarching research interests revolve around the identification of novel anti-infective strategies to tackle antimicrobial drug resistance. My research focuses mainly on the discovery of anti-infectives that selectively disrupt virulence-mediated pathways without interfering with microbial cell viability or by modulating the host natural immune defences to eliminate the pathogen.
To achieve the identification of alternative therapeutic molecules, I adopted the nematode Caenorhabditis elegans, as an in vivo model to select for novel anti-infective compounds against various human pathogens. Additionally, part of my current research also involved the use C. elegans model for toxicity testing and the study of bacterial virulence factors, including bacterial toxins and biofilm formation.
In the immediate future, my goal is to understand the underlying mechanistic insights of the immunomodulatory and anti-virulence activities of the selected anti-infective candidates. Employing a multidisciplinary approach, I work closely with the researchers of different backgrounds to understand the chemical properties of the compounds and to elucidate the drug-protein interactions using an in silico molecular modelling approach. A combination of molecular biology, biochemistry and structural docking approaches can delineate the most promising molecule for future development as anti-infective therapeutics.