Dr. Bruna de Falco is a Post-doctoral Research Fellow at School of Pharmacy in mass spectrometry-based metabolic flux analysis of metabolic pathways for the Green Chemicals Beacon of Excellence (BoE) within the Centre for Analytical Bioscience (CAB). Prior to this position she was a Post-doctoral Research Assistant at Abertay University (Dundee, Scotland) modeling the pathways of toxicant formation in emissions from heated vaporized nicotine delivery devices. She obtained her PhD in Metabolomic Fingerprinting of Food Plants by Nuclear Magnetic Resonance Spectroscopy and Gas Chromatography/Mass Spectrometry at Department of Agricultural Sciences, University of Naples Federico II (Italy).
Extraction, purification and elucidation of primary and secondary metabolites from natural products (e.g. marine sponges, plants, yeasts).
Isolation and purification by using chromatographic techniques (e.g. TLC, UHPLC).
Compound identification by 1H and 13C NMR spectroscopy.
Metabolomic analysis based on NMR spectroscopy and mass spectrometry techniques.
Ultrasounds assisted extraction, antioxidant activity, total phenol content, antibacterial and anti-fungal activity of plant extracts.
Dr. Bruna de Falco is involved in mass spectrometry-based metabolic flux analysis and computational modelling of metabolic pathways project for the Green Chemicals Beacon of Excellence (BoE) within… read more
LAURA GRAUSO, MARIO ZOTTI, WEN SUN, BRUNA DE FALCO, VIRGINIA LANZOTTI and GIULIANO BONANOMI, 2019. Spectroscopic and multivariate data‐based method to assess the metabolomic fingerprint of Mediterranean plants Phytochemical Analysis. 30(5), 572-581 BRUNA DE FALCO, ALBERTO FIORE, ROCCO BOCHICCHIO, MARIANA AMATO and VIRGINIA LANZOTTI, 2018. Metabolomic analysis by UAE-GC MS and antioxidant activity of Salvia hispanica (L.) seeds grown under different irrigation regimes Industrial Crops & Products. 112, 584-592
BRUNA DE FALCO and VIRGINIA LANZOTTI, 2018. NMR spectroscopy and mass spectrometry in metabolomics
analysis of Salvia Phytochemistry Reviews. 17(5), 951-972
Dr. Bruna de Falco is involved in mass spectrometry-based metabolic flux analysis and computational modelling of metabolic pathways project for the Green Chemicals Beacon of Excellence (BoE) within the Centre for Analytical Bioscience (CAB) facility, School of Pharmacy. She is performing experimental design for mass spectrometry-based flux analysis and data collection, and integration of fluxomics data with metabolic pathway and data visualisation methods. The main area of application is in bacterial metabolic engineering and use of stable isotope assisted metabolomics/fluxomics methods to generate mathematical models of metabolic flux.