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Christophe Wiart

Associate Professor, Faculty of Science

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Biography

Wikipedia:

Dr. Christophe Wiart has been studying the medicinal plants of India, Southeast Asia and China for the last 16 years. He has collected, identified and classified several hundred species of medicinal plants and he is regarded as the most prominent authority in the field of Asian ethnopharmacology, chemotaxonomy and ethnobotany. Based in the School of Pharmacy of the University of Nottingham (Malaysia Campus)], he currently supervises several PhD students working on the discovery of novel antibacterial, anticancer, and antioxidant principles from rare plants from the rainforest of Southeast Asia.

Dr. Christophe Wiart has authored several books of which:

1.Wiart C., (2000), Medicinal Plants of Southeast Asia, Pelanduk Publisher, Kuala Lumpur.100pp.[3]

2.Wiart C. and Kumar A., (2000), Practical Handbook of Pharmacognosy, Prentice Hall, Kuala Lumpur.100pp

3.Wiart C., (2002), Medicinal Plants of Southeast Asia, second edition, Prentice Hall, Kuala Lumpur. Preface of Professor Guy Mazars, (University Louis Pasteur, Strasbourg, President of The European Society of Ethnopharmacology) and reviewed by Professor Waterman (South Cross University, Australia).300pp.

4.Wiart C (2005), "Antibacterial activity of medicinal plants used for traditional medicine in the State of Perak, Malaysia". In Ethnomedicine, Der Grosse Leibeiker, Germany.

5.Wiart C., (2006), Medicinal Plants of the Asia-Pacific: Drugs from the Future? WorldScientific, Singapore. Preface of Professor Norman Farnsworth (University of Illinois, USA), Professor Nina Etkin (University of Hawaii) and Professor Elizabeth Williamson (London, UK). 800pp.[4]

6.Wiart C., (2006), Ethnopharmacology of Medicinal Plants: Asia and the Pacific. Humana Press, USA. 400pp.

7.Wiart C., (2006), Medicinal Plants of Asia and the Pacific CRC Press, USA. 300 pp.

8.Wiart C.,(2009), Medicinal Plants from the East. University of Nottingham Press, UK. 800 pp.

9.Wiart C., (2010), Medicinal Fruit Trees of Southeast Asia. In Genetic Resources, chromosome engineering, and crop improvement edited by Ram J. Singh. Vol.

Expertise Summary

Specialized in the discovery of novel antibiotics, antiviral , anti-parasite or anticancer agents from tropical rainforest plants and from medicinal plants used in Southeast Asia. My field of expertise encompasses collection of medicinal plants, identification, ethnopharmacology and in vitro pharmacological testing.

Published several books in the US, UK, and Singapore on the medicinal plants of Asia and their pharmacological potentials.

General secretary and editor in chief of the Asian Society of Pharmacognosy and editor in chief of the Asian Journal of Pharmacognosy

TV Appearances: Appeared on HBO's Vice (TV Series) in season 3, episode 6 (episode 28 of the series), titled "The Post-Antibiotic World & Indonesia's Palm Bomb." This episode aired on April 17, 2015. [5] This episode highlighted the need to find new treatments for infections that were previously treatable with antibiotics, but are now resistant to multiple drugs. "The last hope for the human race's survival, I believe, is in the rainforests of tropical Asia," said ethnopharmacologist Dr. Christophe Wiart. "The pharmaceutical wealth of this land is immense."

Appeared on Aljazeera Inside Story " For only the fourth time in its 70-year history, the United Nations is holding a special meeting devoted to a health crisis.

http://www.aljazeera.com/programmes/insidestory/2016/09/rise-superbugs-resistance-futile-160921203404802.html

It is discussing the rise of drug-resistant bacteria and how to treat them.

Doctors and scientists have long warned about the problem, which is being propelled by the way antibiotics are misused.

And that is threatening the lives of millions of people around the world - along with the global economic output.

So, what can be done to stop the threat of drug-resistant bacteria?

Presenter: Adrian Finighan

Guests:

Sally Davies - Chief medical officer for England

Jim O'Neill - Chairman of the UK-commissioned review on antimicrobial resistance

Rohit Malpani - Director of policy and analysis for Doctors Without Borders

Christophe Wiart - Specialist in the discovery of antibiotics in Southeast Asia

Teaching Summary

My teaching is limited to few hours a semester. Most of my time goes to research and book writing.

Research Summary

Discovery of antibiotics from medicinal plants in Asia

Drug discovery from medicinal plants used in India, Bangladesh, Vietnam, Burma, Thailand, Cambodia, Malaysia, Philippines and Indonesia.

-Botany: Field collection, identification, taxonomy. Choice of strategic plants according to the pharmacological activities or principles desired.

-Phytochemistry: Extraction and purification of plant extracts using TLC, GC-MS, HPLC, and NMR.

-Pharmacy: Choice of the best galenical forms as well as ingredients for a maximal pharmacological activity.

-Pharmacology: The knowledge acquired allows the guidance and direction of in vitro or in vivo pharmacological activities of natural products and/or extracts in the following fields: oncology (cancer cells), virology (proliferation of HIV in cells), bacteriology (culture of bacteria), neurology, cardiovascular system and others.

-Toxicology: The knowledge acquired allows the guidance and direction of in vitro or in vivo toxicity of natural products and/or extracts.

-Others Lecturing pharmacognosy, publications and oral presentation in international symposia. Consultations. PhD supervisor. Writing of academic books.

Recent Publications

http://www.aljazeera.com/programmes/insidestory/2016/09/rise-superbugs-resistance-futile-160921203404802.html

http://www.medicaldaily.com/pulse/post-antibiotic-world-vice-travels-doctors-looking-solution-antibiotic-resistance-329514

Past Research

Screening of several plant species for antimicrobial, antioxidant and anticancer activity.

Isolation of antibacterial, cytotoxic and antioxidant principles from selected rainforest plants for drug development.

Future Research

Drug discovery from medicinal plants used in India, Bangladesh, Vietnam, Burma, Thailand, Cambodia, Malaysia, Philippines and Indonesia.

-Botany: Field collection, identification, taxonomy. Choice of strategic plants according to the pharmacological activities or principles desired.

-Phytochemistry: Extraction and purification of plant extracts using TLC, GC-MS, HPLC, and NMR.

-Pharmacy: Choice of the best galenical forms as well as ingredients for a maximal pharmacological activity.

-Pharmacology: The knowledge acquired allows the guidance and direction of in vitro or in vivo pharmacological activities of natural products and/or extracts in the following fields: oncology (cancer cells), virology (proliferation of HIV in cells), bacteriology (culture of bacteria), neurology, cardiovascular system and others.

-Toxicology: The knowledge acquired allows the guidance and direction of in vitro or in vivo toxicity of natural products and/or extracts.

-Others Lecturing pharmacognosy, publications and oral presentation in international symposia. Supervision of Masters and PhD. Consultation and patenting. Writing of academic books.

School of Pharmacy

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