School of Pharmacy

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Eleonora Comeo

Research Associate, Faculty of Science

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Biography

I obtained my MSc in Chemistry and Pharmaceutical Technologies from the Alma Mater Studiorum University of Bologna in December 2016. Following the award of the University of Bologna School of Pharmacy's study grant for dissertations abroad, I completed my thesis research project at the University of Helsinki under the supervision of Dr Simo Vanni in computational neuroscience. On the same year I was awarded a Erasmus + grant by the European Commission to undertake a three-month internship between Feb-May 2017 in the research lab of Prof. Barrie Kellam at the University of Nottingham School of Pharmacy where I focused on the design and synthesis of novel fluorescently-labelled analogues of the b2-adrenergic receptor antagonist propranolol to be applied for in vivo studies. In July 2017 I obtained the professional qualification as Pharmacist. Following an experience in industry working as research chemist for a CRO company, I embarked on a 4-year PhD program in Molecular Pharmacology and Drug Discovery joint between the University of Nottingham and Monash University (Australia) working under the supervision of Professors Barrie Kellam and Stephen J Hill in Nottingham and Prof Peter Scammells, Dr. Lauren T. May and A/P Michelle Halls at the Monash Institute of Pharmaceutical Sciences (MIPS). The focus of my PhD was the rational (structure-based) design, development and application of novel subtype-selective fluorescent probes to improve the understanding of the molecular pharmacology of the adenosine A1 and A2A receptors in living cells. In October 2021 I took a Postdoctoral Research Associate position in Professor Michael Stocks' laboratory where I will be working on a Prosperity Partnership Project between the Universities of Nottingham and Strathclyde and GSK.

Research Summary

I am currently interested in the development and application of novel synthetic organic and medicinal chemistry approaches aimed at supporting an Artificial Intelligence (AI)-enabled medicinal… read more

Recent Publications

Current Research

I am currently interested in the development and application of novel synthetic organic and medicinal chemistry approaches aimed at supporting an Artificial Intelligence (AI)-enabled medicinal chemistry program working in collaboration with scientists across the Universities of Nottingham and Strathclyde and GSK.

Other areas of research include the rational design, development and application of novel fluorescent probes for GPCR, with a focus on adenosine receptors, thereby supporting a better understanding on how these membrane receptor work in native expressing systems and, possibly, supporting the identification of new site or mechanisms for therapeutic intervention.

School of Pharmacy

University of Nottingham
University Park
Nottingham, NG7 2RD

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