Jatin completed his undergraduate MChem degree in Pharmaceutical Chemistry at the University of Leicester. This included a research project in the area of molecularly imprinted polymer nanoparticles under the supervision of Prof Sergey Piletsky. He was also awarded the 2015 Celltech Prize for top graduating pharmaceutical chemist.
Jatin has one year research and development experience in materials science at Pfizer (Sandwich, UK) where he had the position of industrial trainee. His work there involved the physical and analytical characterisation of active pharmaceutical ingredients in their solid form. Jatin has previously been involved as a STEM ambassador.
In September 2015, Jatin joined the CDT in Advanced Therapeutics and Nanomedicines. During his first year he completed two training projects. The first projected focused on the immunomodulation activity of natural lipophilic cannabinoids under the supervision of Dr. Pavel Gershkovich. Key techniques used involved HPLC, ELISA and pharmacokinetic analysis. The second training project was focused on the development of breath figure array polymer films for biomaterial applications. This project was completed as a visiting research student at the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS) (Glasgow, UK). Key techniques used include spin-coating, AFM and contact angle goniometry (CAG).
Project Title: Analysis of skin permeation of pharmaceuticals and cosmetics.
Supervisors: Dr. David Scurr, Professor David Barrett, Dr. Josephine Bunch, Dr Judata Wibawa and Dr Helen Dearie.
Industrial Sponsor: Walgreens Boots Alliance
Project Details: Current understanding of skin permeation of topically applied drugs is limited particularly regarding the route or mechanism of stratum corneum penetration and the permeation distribution of drug compounds. More detailed analysis in aforementioned areas using advanced analytical techniques would advance knowledge of dermal and transdermal drug delivery so that more efficacious topical drug products can be developed.
ZGAIR, ATHEER, WONG, JONATHAN CM, LEE, JONG BONG, MISTRY, JATIN, SIVAK, OLENA, WASAN, KISHOR M, HENNIG, IVO M, BARRETT, DAVID A, CONSTANTINESCU, CRIS S, FISCHER, PETER M and GERSHKOVICH, PAVEL, 2016. Dietary fats and pharmaceutical lipid excipients increase systemic exposure to orally administered cannabis and cannabis-based medicines. American Journal of Translational Research. 8(8), 3448-59
MISTRY, JATIN, GUERREIRO, ANTONIO, MOCZKO, EWA, PILETSKA, ELENA, KARIM, KAL and PILETSKY, SERGEY A, 2015. Analysis of cooperative interactions in molecularly imprinted polymer nanoparticles. Molecular Imprinting. 3(1), 55-64