School of Pharmacy
  • Print
   
   

Image of Napoleon Nikolaos Vrettos

Napoleon Nikolaos Vrettos

Postgraduate Research Student,

Contact

Biography

I studied Pharmacy in National Kapodistrian University of Athens and graduated with an upper second class with honours. My undergraduate studies were followed by a Master of Science (MSc) in Pharmaceutical Technology at King's College London from which I graduated with Distinction. My research project was concerned with the development of novel liposomal formulations bound to deliver a new antibiotic agent into the lungs via inhalation to treat Pseudomonas aeruginosa infections in patients in cystic fibrosis. During that project, I developed the formulations, tested their physical stability and assessed their encapsulation efficiency for the novel antibiotic agent. Afterwards, the in vitro efficacy of drug-loaded liposomes was assessed in cooperation with Public Health England and was found very promising. The project is still under development.

After my studies at King's, I worked as a Quality Control Analyst for few months, followed by employment as an R&D Analytical Scientist at GlaxoSmithKline in the late-stage development of oral anti-HIV products for one year. My work was concerned with assisting formulation development of new products, developing analytical methods for HPLC and dissolution testing, doing method validation and carrying out stability and clinical batch analysis.

Currently, I am a PhD Student in the Division of Molecular Therapeutics and Formulation, University of Nottingham. My project is concerned with the development of a sustained release delivery system for a novel antihypertensive drug.

Expertise Summary

Experienced in developing analytical methods and assisting formulation development at an industrial scale following cGMP and ICH guidelines.

Knowledgeable of novel formulation development.

Currently, under formulation PhD training.

Teaching Summary

Interested in getting more knowledge and experience in novel formulation development by means of novel techniques, including 3D Printing.

Research Summary

Development of a Sustained Release Delivery system for a novel antihypertensive drug

Supervisor 1: Dr Zheying Zhu

Supervisor 2: Professor Clive Roberts

Past Research

Optimisation of a novel inhaled liposomal formulation for treatment of Pseudomonas aeruginosa pulmonary infections in patients with cystic fibrosis (King's College London, United Kingdom)

Development of new oral anti-HIV products, R&D Analytical Department (GlaxoSmithKline, United Kingdom)

Future Research

Nano crystals, 3D Printing

School of Pharmacy

University of Nottingham
University Park
Nottingham, NG7 2RD

For all enquiries please visit:
www.nottingham.ac.uk/enquiry