Contact

• workRoom D207, BDI3 Biodiscovery Institute
  University Park
  Nottingham
  NG7 2RD
  UK
• Hoda.Eltaher@nottingham.ac.uk
• https://orcid.org/0000-0001-5602-2696

Biography

Following an MSc in pharmaceutical formulation sciences, I received a PhD in drug delivery and tissue engineering at the University of Nottingham, UK. Since then, I continued a series of collaborative research projects in the fields of drug delivery, biomedical engineering, and regenerative medicine at Alexandria University, Egypt.

The focus of my current work in the Dixon group at the division of Regenerative Medicine and Cellular Therapies is to optimize the multi factors involved in the development of the GET peptide-gene nanoparticles for regenerative, lung gene therapy and immunization applications in preclinical animal studies aiming for clinical translation.

Teaching Summary

AFHEA, Associate Fellow of Higher Education Academy.

At the University of Nottingham, UK, I participated in:

• Pharmacy MPharm (SPR1 23-24): Future Medicines (PHAR4014 UNUK)
• Stem Cell Technology and Regenerative Medicine MSc (SPR1 23-24): Translational Technologies for Stem Cells - Tissue Engineering
• Practical Courses for Pharmacy Undergraduate Students (Medicines Manufacturing) (2015/2016).

In Egypt:

• Undergraduates (2016-2019): Biopharmaceutics and Pharmacokinetics (PT609) and Clinical Pharmacokinetics (PP907) at Alexandria University, Egypt.
• Undergraduates (2017-2019): Module Lead in Biopharmaceutics (PCS424) and Pharmacokinetics (PCS322) at Arab Academy for Science, Technology and Maritime Transport, EGYPT.
• Postgraduates (2016-2019, Alexandria University, Egypt): Advanced drug delivery (0901803), Regenerative Medicine & Biomaterials (0901804) for PhD in Pharmaceutics program & Pharmaceutical Services II (0901606) for Hospital Pharmacy Diploma program.
• Participated in Pharmaceutics Practical Courses teaching for Pharmacy undergraduate students (Y1-4) (Egypt, 2006-2010)

Research Summary

Mucus-penetrating Peptide Gene nanoparticles for lung gene therapy Peptide Gene nanoparticles for immunization applications Wound healing and skin regeneration using electrospinning, hydrogel… read more

Selected Publications

• WALAA M METWALLY, SALMA E EL-HABASHY, LOBNA S EL-HOSSEINY, MARWA M ESSAWY, LABIBA K EL-KHORDAGUI and HODA M ELTAHER, 2023. Bioinspired 3D-printed scaffold embedding DDAB-nano ZnO/nanofibrous microspheres for regenerative diabetic wound healing Biofabrication. 16(1), 015001
• SAHRISH REHMANI, CHRISTOPHER M. MCLAUGHLIN, HODA M. ELTAHER, R. CHARLOTTE MOFFETT, PETER R. FLATT and JAMES E. DIXON, 2023. Orally-delivered insulin-peptide nanocomplexes enhance transcytosis from cellular depots and improve diabetic blood glucose control Journal of Controlled Release. 360, 93-109
• HODA M. ELTAHER, LIA A. BLOKPOEL FERRERAS, AVEEN R. JALAL and JAMES E. DIXON, 2022. Direct contact-mediated non-viral gene therapy using thermo-sensitive hydrogel-coated dressings Biomaterials Advances. 143, 213177
• HODA M. ELTAHER, FATIMA E. ABUKUNNA, LAURA RUIZ-CANTU, ZACK STONE, JING YANG and JAMES E. DIXON, 2020. Human-scale tissues with patterned vascular networks by additive manufacturing of sacrificial sugar-protein composites Acta Biomaterialia. 113, 339-349

• View all publications

Current Research

• Mucus-penetrating Peptide Gene nanoparticles for lung gene therapy
• Peptide Gene nanoparticles for immunization applications
• Wound healing and skin regeneration using electrospinning, hydrogel casting and/or 3D printing
• Bone regeneration using 3D printing, drug and gene delivery nanoparticles
• Improving drug permeation to intestinal, skin and mucosal barriers using nano lipids delivery systems

• HEBA A. FAYYAZ, MAGDA A. EL-MASSIK, MOHAMMED BAHEY-EL-DIN, AMANY ABDEL-BARY, OSSAMA Y. ABDALLAH and HODA M. ELTAHER, 2024. Targeted DPPC/DMPG surface-modified voriconazole lipid nanoparticles control invasive pulmonary aspergillosis in immunocompromised population: in-vitro and in-vivo assessment International Journal of Pharmaceutics. 649, 123663
• DIXON, JAMES E., WELLINGTON, VANESSA, ELNIMA, ALAA and ELTAHER, HODA M., 2024. Effects of Microenvironment and Dosing on Efficiency of Enhanced Cell Penetrating Peptide Nonviral Gene Delivery ACS Omega. 9(4), 5014-5023
• LABIBA KHALIL EL-KHORDAGUI, HODA MAHER ELTAHER and SOMIRAA SAMIR SAID, 2023. Chapter 4 - Biomedical applications of bio-degradable green composites. In: DR. INAMUDDIN and TARIQ ALTALHI, eds., Green Sustainable Process for Chemical and Environmental Engineering and Science Elsevier. 55-110
• WALAA M. METWALLY, SALMA E. EL-HABASHY, NEFERTITI A. EL-NEKHILY, HODA E. MAHMOUD, HODA M. ELTAHER and LABIBA EL-KHORDAGUI, 2023. Nano zinc oxide-functionalized nanofibrous microspheres: A bioactive hybrid platform with antimicrobial, regenerative and hemostatic activities International Journal of Pharmaceutics. 122920
• SAHRISH REHMANI, CHRISTOPHER M. MCLAUGHLIN, HODA M. ELTAHER, R. CHARLOTTE MOFFETT, PETER R. FLATT and JAMES E. DIXON, 2023. Orally-delivered insulin-peptide nanocomplexes enhance transcytosis from cellular depots and improve diabetic blood glucose control Journal of Controlled Release. 360, 93-109
• WALAA M METWALLY, SALMA E EL-HABASHY, LOBNA S EL-HOSSEINY, MARWA M ESSAWY, LABIBA K EL-KHORDAGUI and HODA M ELTAHER, 2023. Bioinspired 3D-printed scaffold embedding DDAB-nano ZnO/nanofibrous microspheres for regenerative diabetic wound healing Biofabrication. 16(1), 015001
• SALEH, NESSRIN, MAHMOUD, HODA E., ELTAHER, HODA, HELMY, MAGED, EL-KHORDAGUI, LABIBA and HUSSEIN, AHMED A., 2022. Prodigiosin-Functionalized Probiotic Ghosts as a Bioinspired Combination Against Colorectal Cancer Cells Probiotics and Antimicrobial Proteins.
• HODA M. ELTAHER, LIA A. BLOKPOEL FERRERAS, AVEEN R. JALAL and JAMES E. DIXON, 2022. Direct contact-mediated non-viral gene therapy using thermo-sensitive hydrogel-coated dressings Biomaterials Advances. 143, 213177
• SALMA E. EL-HABASHY, HODA M. ELTAHER, AHMED GABALLAH, EIMAN I. ZAKI, RADWA A. MEHANNA and AMAL H. EL-KAMEL, 2021. Hybrid bioactive hydroxyapatite/polycaprolactone nanoparticles for enhanced osteogenesis Materials Science and Engineering: C. 119, 111599
• MOHAMED R. EL-AASSAR, NAGHAM G. EL-BEHERI, MONA M. AGWA, HODA M. ELTAHER, MOSTAFA ALSEQELY, WAGIH S. SADIK and LABIBA EL-KHORDAGUI, 2021. Antibiotic-free combinational hyaluronic acid blend nanofibers for wound healing enhancement International Journal of Biological Macromolecules. 167, 1552 - 1563
• OMAR A. HAMID, HODA M. ELTAHER, VIRGINIE SOTTILE and JING YANG, 2021. 3D bioprinting of a stem cell-laden, multi-material tubular composite: An approach for spinal cord repair Materials Science and Engineering: C. 120, 111707
• EL-HABASHY, S., ELTAHER, H., GABALLAH, A., MEHANNA, R. and EL-KAMEL, A. H., 2021. Biomaterial-Based Nanocomposite for Osteogenic Repurposing of Doxycycline: Int J Nanomedicine Int J Nanomedicine. 16, 1103-1126
• EL-HABASHY, SALMA E., EL-KAMEL, AMAL H., ESSAWY, MARWA M., ABDELFATTAH, ELSAYEDA-ZEINAB A. and ELTAHER, HODA M., 2021. Engineering 3D-printed core–shell hydrogel scaffolds reinforced with hybrid hydroxyapatite/polycaprolactone nanoparticles for in vivo bone regeneration Biomater. Sci.. 9, 4019-4039
• SALMA E. EL-HABASHY, AMAL H. EL-KAMEL, MARWA M. ESSAWY, ELSAYEDA-ZEINAB A. ABDELFATTAH and HODA M. ELTAHER, 2021. 3D printed bioinspired scaffolds integrating doxycycline nanoparticles: Customizable implants for in vivo osteoregeneration International Journal of Pharmaceutics. 607, 121002
• MOHAMED G. EL-MELEGY, HODA M. ELTAHER, AHMED GABALLAH and AMAL H. EL-KAMEL, 2021. Enhanced oral permeability of Trans-Resveratrol using nanocochleates for boosting anticancer efficacy; in-vitro and ex-vivo appraisal European Journal of Pharmaceutics and Biopharmaceutics. 168, 166-183
• LAMIAA M. ABDEL-RAHMAN, HODA M. ELTAHER, KAMILIA ABDELRAOUF, MOHAMMED BAHEY-EL-DIN, CHERINE ISMAIL, EL-REFAIE S. KENAWY and LABIBA K. EL-KHORDAGUI, 2020. Vancomycin-functionalized Eudragit-based nanofibers: Tunable drug release and wound healing efficacy Journal of Drug Delivery Science and Technology. 58, 101812
• HODA M. ELTAHER, FATIMA E. ABUKUNNA, LAURA RUIZ-CANTU, ZACK STONE, JING YANG and JAMES E. DIXON, 2020. Human-scale tissues with patterned vascular networks by additive manufacturing of sacrificial sugar-protein composites Acta Biomaterialia. 113, 339-349
• SOMIRAA S. SAID, HODA M. ELTAHER and LABIBA K. EL-KHORDAGUI, 2019. Chapter 5 - Biomedical applications of composite resorbable fibers. In: VALENTINA GRUMEZESCU and ALEXANDRU MIHAI GRUMEZESCU, eds., Materials for Biomedical Engineering Elsevier. 127 - 155
• HODA M. ELTAHER, SOMIRAA S. SAID and LABIBA K. EL-KHORDAGUI, 2018. 13 - Drug delivery for cardiac regeneration. In: INAMUDDIN, ABDULLAH M. ASIRI and ALI MOHAMMAD, eds., Applications of Nanocomposite Materials in Drug Delivery Woodhead Publishing. 283 - 321
• PARMENTER, CHRISTOPHER D. J., FAY, MICHAELW., HARTFIELD, CHERYL and ELTAHER, HODA M., 2016. Making the Practically Impossible "Merely Difficult"-Cryogenic FIB Lift-Out for "Damage Free" Soft Matter Imaging MICROSCOPY RESEARCH AND TECHNIQUE. 79(4), 298-303
• ELTAHER HM, YANG J, SHAKESHEFF K and DIXON JE, 2016. Highly efficient intracellular transduction in three-dimensional gradients for programming cell fate Acta Biomaterialia. 41, 181-192