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Due to the high output of research related to quorum sensing, we have decided not to include new quorum sensing references. However, if you would like a link to your own personal website then please contact either steve.atkinson@nottingham.ac.uk or steve.diggle@nottingham.ac.uk

Adar, Y.Y., Simaan, M. and Ulitzur, S.  (1992)  Formation of the LuxR protein in the Vibrio fischeri system is controlled by HtpR through the GroESL proteins.  J. Bacteriol. 174, 7138-7143.

Adar, Y.Y. and Ulitzur, S.  (1993)  GroESL proteins facilitate binding of externally added inducer by LuxR protein-containing E. coli cells.  J. Biolumin. Chemilumin. 8, 261-266.

Aendekerk, S., Diggle, S. P., Song, Z., Hoiby, N., Cornelis, P., Camara, M. and Williams, P. (2005) The MexGHI-OpmD multidrug efflux pump controls fitness, antibiotic susceptibility and virulence in Pseudomonas aeruginosa via 4-quinolone-dependent cell-to-cell communication. Microbiology. 151, 1113-1125.

Albus, A.M., Pesci, E.C., Runyen-Janecky, L.J., West, S.E.H. and Iglewski, B.H.  (1997) Vfr controls quorum sensing in Pseudomonas aeruginosa.  J. Bacteriol.  179, 3928-3935.

Anderson, R.M., Zimprich, C.A. and Rust, L.  (1999)  A second operator is involved in Pseudomonas aeruginosa elastase (lasB) activation.  J. Bacteriol.  181, 6264-6270.

Atkinson, S., Throup, J.P., Stewart, G.S.A.B. and Williams, P.  (1999)  A hierarchical quorum-sensing system in Yersinia pseudotuberculosis is involved in the regulation of motility and clumping.  Mol. Microbiol.  33, 1267-1277.

Balaban, N., Goldkorn, T., Nhan, R. T., Dang, L. B., Scott, S., Ridgley, R. M., Rasooly, A., Wright, S. C., Larrick, J. W., Rasooly, R. and Carlson, J. R. (1998) Autoinducer of virulence as a target for vaccine and therapy against Staphylococcus aureus. Science 280, 438-440.

Balaban, N., Collins, L. V., Cullor, J. S., Hume, E. B., Medina-Acosta, E., Vieira da Motta, O., O'Callaghan, R., Rossitto, P. V., Shirtliff M. E., Serafim da Silveira, L., Tarkowski, A., Torres, J. V. (2000) Prevention of diseases caused by Staphylococcus aureus using the peptide RIP. Peptides 21, 1301-1311.

Bainton, N.J., Bycroft, B.W., Chhabra, S.R., Stead, P., Gledhill, L., Hill, P., Rees, C.E.D., Winson, M.K., Salmond, G.P.C., Stewart, G.S.A.B. and Williams, P.  (1992)  A general role for the lux autoinducer in bacterial cell signaling:  Control of antibiotic biosynthesis in Erwinia.  Gene 116, 87-91.

Bainton, N.J., Stead, P., Chhabra, S.R., Bycroft, B.W., Salmond, G.P.C., Stewart, G.S.A.B. and Williams, P.  (1992)  N-(3-oxohexanoyl)-L-homoserine lactone regulates carbapenem antibiotic production in Erwinia carotovora.  Biochem. J. 288, 997-1004.

Bassler, B.L., Wright, M., Showalter, R.E. and Silverman, M.R.  (1993)  Intercellular signalling in Vibrio harveyi:  Sequence and function of genes regulating expression of luminescence.  Mol. Microbiol. 9, 773-786.

Bassler, B.L., Wright, M. and Silverman, M.R.  (1994)  Sequence and function of LuxO, a negative regulator of luminescence in Vibrio harveyi.  Mol. Microbiol.  12, 403-412.

Bassler, B.L., Wright, M. and Silverman, M.R.  (1994)  Multiple signaling systems controlling expression of luminescence in Vibrio harveyi:  Sequence and function of genes encoding a  second sensory pathway.  Mol. Microbiol. 13, 273-286.

Bassler, B.L.  (1999)  How bacteria talk to each other: regulation of gene expression by quorum sensing.  Curr. Op. Microbiol.  2, 582-587.

Batchelor, S.E., Cooper, M., Chhabra, S.R., Glover, L.A., Stewart, G.S.A.B., Williams, P. and Prosser, J.I.  (1997)  Cell density-regulated recovery of starved biofilm populations of ammonia-oxidising bacteria.  Appl. Environ. Microbiol. 63, 2281-2286.

Beck von Bodman, S. and Farrand, S.K.  (1995)  Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.  J. Bacteriol.  177, 5000-5008.

Beck von Bodman, S., Majerczak, D.R. and Coplin, D.L.  (1998)  A negative regulator mediates quorum-sensing contol of exopolysaccharide production in Pantoea stewartii subsp. stewartii. Proc. Natl. Acad. Sci. USA  95, 7687-7692.

Bibb, M.  (1996)  The regulation of antibiotic production in Streptomyces coelicolor A3(2).  Microbiology.  142, 1335-1344.

Brint, J. M. & Ohman, D. E. (1995) Synthesis of multiple exoproducts in Pseudomonas aeruginosa is under the control of RhlR-RhlI, another set of regulators in strain PAO1 with homology to the autoinducer-responsive LuxR-LuxI family. J. Bacteriol. 177, 7155-7163.

Burgess, N.A., Kirke, D.F., Curtis, M.A., Meyers, N.L., Williams, P. and Camara, M. (2001) Role of GinS, a LuxS homologue in Porphyromonas gingivalis. ASM Conference on Cell-Cell Communication in Bacteria, Snowbird, Utah, Abstract 44.

Burgess, N. A., Kirke, D. F. , Williams, P., Winzer, K, Hardie, K. R., Meyers, N. L, Aduse-Opoku, J., Curtis, M. A and Camara, M. (2002) LuxS-dependent quorum sensing in Porphyromonas gingivalis modulates protease and haemagglutinin activities but is not essential for virulence. Microbiology, 148, 763-772.

Calfee, M. W., Coleman, J. P. and Pesci, E. C. (2001) Interference with Pseudomonas quinolone signal synthesis inhibits virulence factor expression by Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. USA. 98, 11633-11637.

Cámara, M., Daykin, M. and Chhabra, S.R. (1998) Detection, purification and synthesis of N-acyl homoserine lactone quorum sensing molecules. Methods in Microb. Bacterial Pathogenesis. 27, 319-330.

Cámara M, Williams, P., Hardman, A. and Milton, D. (2002) Quorum sensing in Vibrio cholerae. Nature Genetics. 32, 217-18.

Cámara, M., Williams, P. and Hardman, A.(2002) Controlling infection by tuning down the volume of bacterial small-talk. The Lancet Infectious Diseases. 2, 667-676.

Cao, J. and Meighen, E.A.  (1989)  Purification and structural identification of an autoinducer for the luminescence system of Vibrio harveyi.  J. Biol. Chem.  21, 21670-21676.

Chapon-Hervé, V., Akrim, M., Latifi, A., Williams, P., Lazdunski, A. and Bally, M.  (1997)  Regulation of the xcp secretion pathway by multiple quorum-sensing modulons in Pseudomonas aeruginosa.  Mol. Microbiol.  24, 1169-1178.

Chernin, L.S., Winson, M.K., Thompson, J.M., Haran, S., Bycroft, B.W., Chet, I., Williams, P. and Stewart, G.S.A.B.  (1998)  Chitinolytic activity in Chromobacterium violaceum:  Substrate analysis and regulation by quorum sensing.  J. Bacteriol. 180, 4435-4441.

Chhabra, S. R., Stead, P., Bainton, N. J., Salmond, G. P. C., Stewart, G. S. A. B., Williams, P. and Bycroft, B. W.  (1993)  Autoregulation of carbapenem biosynthesis in Erwinia carotovora ATCC 39048 by analogues of N-(3-oxohexanoyl)-L-homoserine lactone.  J. Antibiotics.  46, 441-454.

Chhabra, S.R., Khan, A.N. and Bycroft, B.W. (2000) Solid phase synthesis of symmetrical and unsymmetrical polyamine analogues of philanthotoxins using a Dde-linker. Tetrahedron Letters 41, 1095-1098.

Choi, S.H. and Greenberg, E.P.  (1991)  The C-terminal region of the Vibrio fischeri LuxR protein contains an inducer-independent lux gene activating domain. Proc. Natl. Acad. Sci. USA 88, 11115-11119.

Choi, S.H. and Greenberg, E.P.  (1992)  Genetic disection of DNA binding and luminescence gene activation by the Vibrio fischeri LuxR protein.  J. Bacteriol. 174, 4064-4069.

Chugani, S. A., Whiteley, M., Lee, K. M., D'Argenio, D., Manoil, C. and Greenberg, E. P. (2001) QscR, a modulator of quorum sensing signal synthesis and virulence in Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. USA. 98, 2752-2757.

Collier, D. N., Anderson, L., McKnight, S. L., Noah, T. L., Knowles, M., Boucher, R., Schwab, U., Gilligan, P. and Pesci, E. C. (2002) A bacterial cell to cell signal in the lungs of cystic fibrosis patients. FEMS Microbiol. Lett. 215, 41-46.

Croxatto, A., Chalker V.J., Lauritz, J., Jass, J., Hardman, A., Williams, P., Cámara, M. and Milton, D.L. (2002) VanT, a homologue of Vibrio harveyi LuxR, regulates metalloprotease production, pigment production, and biofilm formation in Vibrio anguillarum. J. Bacteriol. 184, 1617-1629

Davies, D. G., Parsek, M. R., Pearson, J. P. Iglewski, B. H. Costerton, J. W. & Greenberg, E. P. (1998) The involvement of cell-to-cell signals in the development of a bacterial biofilm. Science. 280 295-298.

de Kievit, T., Seed, P.C., Nezezon, J., Passador, L. and Iglewski, B.H.  (1999)  RsaL, a novel repressor of virulence gene expression in Pseudomonas aeruginosa.  J. Bacteriol.  181, 2175-2184.

deKievit, T. R. & Iglewski, B. H. (2000) Bacterial quorum sensing in pathogenic relationships. Infect. Immun. 68, 4839-4849.

Devine, J.H., Countryman, C. and Baldwin, T.O.  (1988)  Nucleotide sequence of the luxR and luxI genes and structure of the primary regulatory region of the lux regulon of Vibrio fischeri ATCC 7744.  Biochemistry 27, 837-842.

Devine, J.H., Shadel, G.S. and Baldwin, T.O.  (1989)  Identification of the operator of the lux regulon from the Vibrio fischeri strain ATCC7744. Proc. Natl. Acad. Sci. USA 88, 5688-5692.

Diggle, S. P., Winzer, K., Camara, M. & Williams, P. (2000) Analysis of novel regulators involved in quorum sensing-dependent virulence gene expression in Pseudomonas aeruginosa. Journal of Pharmacy and Pharmacology. 52 (Supplement): 122.

Diggle, S. P., Winzer, K., Camara, M. & Williams, P. (2000) Growth phase dependency of the Pseudomonas aeruginosa quorum sensing cascade. American Society for Microbiology. 100th Annual General Meeting, Los Angeles, USA.

Diggle, S. P., Winzer, K., Lazdunski, A., Williams, P. and Camara, M. (2002) Advancing the quorum in Pseudomonas aeruginosa: MvaT and the regulation of N-Acylhomoserine lactone production and virulence gene expression. J. Bacteriol. 184, 2576-2586.

Diggle, S. P., Winzer, K., Chhabra, S. R., Worrall, K. E., Camara, M. and Williams, P. (2003) The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density-dependency of the quorum sensing hierarchy, regulates rhl-dependent phenotypes at the onset of stationary phase and can be produced in the absence of LasR. Mol Microbiol. 50, 29-43.

Dolan, K.M. and Greenberg, E.P.  (1992)  Evidence that GroEL, not s³², is involved in transcriptional regulation of the Vibrio fischeri luminescence genes in Escherichia coli.  J. Bacteriol.  174, 5132-5135.

Dong, Y.-H., Xu, J.-L., Li, X.-Z. and Zhang, L.-H.  (2000)  AiiA, an enzyme that inactivates the acylhomoserine lactone quorum-sensing signal and attenuates the virulence of Erwinia carotovora.  Proc. Natl. Acad. Sci. USA, 97, 3526-3531.

Dunlap, P.V. and Greenberg, E.P.  (1985)  Control of Vibrio fischeri luminescence gene expression in Escherichia coli by cyclic AMP and cyclic AMP receptor protein.  J. Bacteriol. 164, 45-50.

Dunlap, P.V. and Greenberg, E.P.  (1988)  Control of Vibrio fischeri lux gene transcription by a cyclic AMP receptor protein-LuxR protein regulatory circuit.  J. Bacteriol. 170, 4040-4046.

Dunlap, P.V.  (1989)  Regulation of luminescence by cyclic AMP in cya-like and crp-like mutants of Vibrio fischeri.  J. Bacteriol. 171, 1199-1202.

Dunlap, P.V. and Ray, J.M.  (1989)  Requirement for autoinducer in transcriptional negative autoregulation of the Vibrio fischeri luxR gene in Escherichia coli.  J. Bacteriol.  171, 3549-3552.

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Dunphy, G., Miyamoto, C. and Meighen, E.  (1997)  A homoserine lactone autoinducer regulates virulence of an insect-pathogenic bacterium, Xenorhabdus nematophilus (Enterobacteriaceae). J. Bacteriol. 179, 5288-5291.

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Eberl, L., Winson, M.K., Sternberg, C., Stewart, G.S.A.B., Christiansen, G., Chhabra, S.R., Bycroft, B.W., Williams, P., Molin, S. and Givskov, M.  (1996)  Involvement of N-acyl-L-homoserine lactone autoinducers in controlling the multicellular behavior of Serratia liquefaciens.  Mol. Microbiol. 20, 127-136.

Egland, K.A. & Greenberg, E.P.  (1999)  Quorum sensing in Vibrio fischeri:  Elements of the luxI promoter.  Mol. Microbiol. 31, 1197-1204.

Engebrecht, J., Nealson, K. and Silverman, M.  (1983)  Bacterial bioluminescence: Isolation and genetic analysis of functions from Vibrio fischeri.  Cell  32, 773-781.

Engebrecht, J. and Silverman, M.  (1984)  Identification of genes and gene products necessary for bacterial bioluminescence.  Proc. Natl. Acad. Sci. USA,  81, 4154-2158.

Engebrecht, J. and Silverman, M.  (1986)  Regulation of expression of bacterial genes for bioluminescence.  In Genetic engineering Setlow, J.K. and Hollaender, A (eds), Plenum, New York, 31-44.

Engebrecht, J. and Silverman, M.  (1987)  Nucleotide sequence of the regulatory locus controlling expression of bacterial genes for bioluminescence.  Nuc. Acids. Res. 15, 10455-10467.

Evans, K., Passador, L., Srikumar, R., Tsang, E., Nezezon, J. and Poole K.  (1998)  Influence of the MexAB-OprM multidrug efflux system on quorum sensing in Pseudomonas aeruginosa.  J. Bacteriol.  180, 5443-5447.

Finch, R. G., Pritchard, D. I., Bycroft, B. W., Williams, P., Stewart, G. S. A. B. (1998) Quorum sensing - a novel target for anti-infective therapy. J. Antimicrob. Chemother. 42, 569-571.

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Freeman, J.A. and Bassler, B.L.  (1999)  A genetic analysis of the function of LuxO, a two-component response regulator involved in quorum-sensing in Vibrio harveyi.  Mol. Microbiol.  31, 665-677.

Freeman, J.A. and Bassler, B.L.  (1999)  Sequence and function of LuxU:  A two-component phosphorelay protein that regulates quorum sensing in Vibrio harveyi.  J. Bacteriol.  181, 899-906.

Fuqua, W.C., Winans, S.C. and Greenberg, E.P.  (1994)  Quorum sensing in bacteria  The LuxR-LuxI family of cell density-responsive transcriptional regulators.  J. Bacteriol. 176, 269-275.

Fuqua, W.C. and Winans, S.C.  (1994)  A LuxR-LuxI type regulatory system activates Agrobacterium Ti plasmid conjugal transfer in the presence of a plant tumour metabolite.  J. Bacteriol. 176, 2796-2806.

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Greenberg, E.P.  (1997)  Quorum sensing in Gram-negative bacteria.  ASM News 63, 371-377.

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Hope, V.J., Milton, D., Hardman, A., Camara, M. and Williams, P.  (1999)  VanM, a homolog to Vibrio harveyi LuxLM is needed for the synthesis of additional N-acyl-homoserine lactones in Vibrio anguillarum.  American Society for Microbiology 99th General Meeting, Chicago 1999, Abstract H-198.

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Kirke, D.F., Lynch, M.J., Swift, S., Bishop, K., Dodd, C.E.R., Keevil, C.W., Stewart, G.S.A.B. and Williams, P.  (1999)  Quorum sensing in Aeromonas hydrophila.  American Society for Microbiology 99th General Meeting, Chicago 1999, Abstract B/D-340.

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