Biomaterials Discovery
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Staff Listing

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Anna Grabowska

Professor of Cancer Microenvironment, Faculty of Medicine & Health Sciences


Research Summary


  • Development of patient-relevant pre-clinical models of cancer incorporating stromal support
  • Role of paracrine signalling in cancer
  • Bioluminescent/fluorescent reporters for real-time imaging
  • Application of interfering RNA technology for target validation
  • Role of cancer stem cells and epithelial-mesenchymal transition (EMT)
  • Effects of hypoxia on tumour biology
  • Transcriptional/translational regulation of cancer-associated genes

Current Research Projects

  • Establishing patient-derived xenograft models
  • Pre-clinical models of cancer for target validation
  • Role of paracrine signalling in induction of EMT and the cancer stem cell-like phenotype
  • Regulation of the mesenchymal stem cell niche
  • Polycations for nucleic acid delivery in cancer
  • Reporters for real-time monitoring of biological processes during cancer development

Recent Publications

Next Generation Biomaterials Discovery

Advanced Materials and Healthcare Technologies, School of Pharmacy, The University of Nottingham
University Park
Nottingham, NG7 2RD

telephone: +44 (0) 115 846 6246