Hoda Eltaher

Contact

• workRoom D207, BDI3 Biodiscovery Institute
  University Park
  Nottingham
  NG7 2RD
  UK
• Hoda.Eltaher@nottingham.ac.uk
• https://orcid.org/0000-0001-5602-2696

Biography

Following a MSc in pharmaceutical formulation sciences, I pursued PhD in drug delivery and tissue engineering at the University of Nottingham, UK. My PhD dissertation "Gradient delivery of bioactive molecules across porous hydrogels" was supervised by Professor Kevin Shakesheff. Since then, I continued a series of collaborative research projects in the fields of drug delivery, biomedical engineering and regenerative medicine in Alexandria university, Egypt.

The focus of my current work in Dixon group at the division of Regenerative Medicine and Cellular Therapies, is to optimize the multi factors involved in the development of the GET peptide-gene nanoparticles for regenerative, lung gene therapy and immunization applications in preclinical animal studies aiming for clinical translation.

Teaching Summary

AFHEA, Associate Fellow of Higher Education Academy, February 2022 to present

I have been involved in academic higher education teaching as an assistant professor for pharmacy under/postgraduate students in Egypt 2016-2019.

• Fall 2016- Fall 2019: Biopharmaceutics and Pharmacokinetics for Undergraduates in Alexandria University and Arab Academy for Science, Technology and Maritime Transport, Egypt.
• Fall 2016-Fall 2019: Postgraduates (Alexandria University, Egypt): PhD in Pharmaceutics & Hospital Pharmacy Diploma
• Teaching Assistant in Pharmaceutics Practical courses teaching for Pharmacy undergraduate students (Egypt) from 2006-2010 and Pharmacy undergraduate students (UK) 2015/2016.

Research Summary

Mucus-penetrating Peptide Gene nanoparticles for lung gene therapy Peptide Gene nanoparticles for immunization applications Wound healing and skin regeneration using electrospinning, hydrogel… read more

Selected Publications

• WALAA M METWALLY, SALMA E EL-HABASHY, LOBNA S EL-HOSSEINY, MARWA M ESSAWY, HODA M ELTAHER and LABIBA K EL-KHORDAGUI, 2023. Bioinspired 3D-printed scaffold embedding DDAB-nano ZnO/nanofibrous microspheres for regenerative diabetic wound healing Biofabrication. 16(1), 015001
• SAHRISH REHMANI, CHRISTOPHER M. MCLAUGHLIN, HODA M. ELTAHER, R. CHARLOTTE MOFFETT, PETER R. FLATT and JAMES E. DIXON, 2023. Orally-delivered insulin-peptide nanocomplexes enhance transcytosis from cellular depots and improve diabetic blood glucose control Journal of Controlled Release. 360, 93-109
• HODA M. ELTAHER, LIA A. BLOKPOEL FERRERAS, AVEEN R. JALAL and JAMES E. DIXON, 2022. Direct contact-mediated non-viral gene therapy using thermo-sensitive hydrogel-coated dressings Biomaterials Advances. 143, 213177
• HODA M. ELTAHER, FATIMA E. ABUKUNNA, LAURA RUIZ-CANTU, ZACK STONE, JING YANG and JAMES E. DIXON, 2020. Human-scale tissues with patterned vascular networks by additive manufacturing of sacrificial sugar-protein composites Acta Biomaterialia. 113, 339-349

• View all publications

Current Research

• Mucus-penetrating Peptide Gene nanoparticles for lung gene therapy
• Peptide Gene nanoparticles for immunization applications
• Wound healing and skin regeneration using electrospinning, hydrogel casting and/or 3D printing
• Bone regeneration using 3D printing, drug and gene delivery nanoparticles
• Improving drug permeation to intestinal, skin and mucosal barriers using nano lipids delivery systems

• LABIBA KHALIL EL-KHORDAGUI, HODA MAHER ELTAHER and SOMIRAA SAMIR SAID, 2023. Chapter 4 - Biomedical applications of bio-degradable green composites. In: DR. INAMUDDIN and TARIQ ALTALHI, eds., Green Sustainable Process for Chemical and Environmental Engineering and Science Elsevier. 55-110
• WALAA M. METWALLY, SALMA E. EL-HABASHY, NEFERTITI A. EL-NEKHILY, HODA E. MAHMOUD, HODA M. ELTAHER and LABIBA EL-KHORDAGUI, 2023. Nano zinc oxide-functionalized nanofibrous microspheres: A bioactive hybrid platform with antimicrobial, regenerative and hemostatic activities International Journal of Pharmaceutics. 122920
• SAHRISH REHMANI, CHRISTOPHER M. MCLAUGHLIN, HODA M. ELTAHER, R. CHARLOTTE MOFFETT, PETER R. FLATT and JAMES E. DIXON, 2023. Orally-delivered insulin-peptide nanocomplexes enhance transcytosis from cellular depots and improve diabetic blood glucose control Journal of Controlled Release. 360, 93-109
• WALAA M METWALLY, SALMA E EL-HABASHY, LOBNA S EL-HOSSEINY, MARWA M ESSAWY, HODA M ELTAHER and LABIBA K EL-KHORDAGUI, 2023. Bioinspired 3D-printed scaffold embedding DDAB-nano ZnO/nanofibrous microspheres for regenerative diabetic wound healing Biofabrication. 16(1), 015001
• SALEH, NESSRIN, MAHMOUD, HODA E., ELTAHER, HODA, HELMY, MAGED, EL-KHORDAGUI, LABIBA and HUSSEIN, AHMED A., 2022. Prodigiosin-Functionalized Probiotic Ghosts as a Bioinspired Combination Against Colorectal Cancer Cells Probiotics and Antimicrobial Proteins.
• HODA M. ELTAHER, LIA A. BLOKPOEL FERRERAS, AVEEN R. JALAL and JAMES E. DIXON, 2022. Direct contact-mediated non-viral gene therapy using thermo-sensitive hydrogel-coated dressings Biomaterials Advances. 143, 213177
• SALMA E. EL-HABASHY, HODA M. ELTAHER, AHMED GABALLAH, EIMAN I. ZAKI, RADWA A. MEHANNA and AMAL H. EL-KAMEL, 2021. Hybrid bioactive hydroxyapatite/polycaprolactone nanoparticles for enhanced osteogenesis Materials Science and Engineering: C. 119, 111599
• MOHAMED R. EL-AASSAR, NAGHAM G. EL-BEHERI, MONA M. AGWA, HODA M. ELTAHER, MOSTAFA ALSEQELY, WAGIH S. SADIK and LABIBA EL-KHORDAGUI, 2021. Antibiotic-free combinational hyaluronic acid blend nanofibers for wound healing enhancement International Journal of Biological Macromolecules. 167, 1552 - 1563
• OMAR A. HAMID, HODA M. ELTAHER, VIRGINIE SOTTILE and JING YANG, 2021. 3D bioprinting of a stem cell-laden, multi-material tubular composite: An approach for spinal cord repair Materials Science and Engineering: C. 120, 111707
• EL-HABASHY, S., ELTAHER, H., GABALLAH, A., MEHANNA, R. and EL-KAMEL, A. H., 2021. Biomaterial-Based Nanocomposite for Osteogenic Repurposing of Doxycycline: Int J Nanomedicine Int J Nanomedicine. 16, 1103-1126
• EL-HABASHY, SALMA E., EL-KAMEL, AMAL H., ESSAWY, MARWA M., ABDELFATTAH, ELSAYEDA-ZEINAB A. and ELTAHER, HODA M., 2021. Engineering 3D-printed core–shell hydrogel scaffolds reinforced with hybrid hydroxyapatite/polycaprolactone nanoparticles for in vivo bone regeneration Biomater. Sci.. 9, 4019-4039
• SALMA E. EL-HABASHY, AMAL H. EL-KAMEL, MARWA M. ESSAWY, ELSAYEDA-ZEINAB A. ABDELFATTAH and HODA M. ELTAHER, 2021. 3D printed bioinspired scaffolds integrating doxycycline nanoparticles: Customizable implants for in vivo osteoregeneration International Journal of Pharmaceutics. 607, 121002
• MOHAMED G. EL-MELEGY, HODA M. ELTAHER, AHMED GABALLAH and AMAL H. EL-KAMEL, 2021. Enhanced oral permeability of Trans-Resveratrol using nanocochleates for boosting anticancer efficacy; in-vitro and ex-vivo appraisal European Journal of Pharmaceutics and Biopharmaceutics. 168, 166-183
• LAMIAA M. ABDEL-RAHMAN, HODA M. ELTAHER, KAMILIA ABDELRAOUF, MOHAMMED BAHEY-EL-DIN, CHERINE ISMAIL, EL-REFAIE S. KENAWY and LABIBA K. EL-KHORDAGUI, 2020. Vancomycin-functionalized Eudragit-based nanofibers: Tunable drug release and wound healing efficacy Journal of Drug Delivery Science and Technology. 58, 101812
• HODA M. ELTAHER, FATIMA E. ABUKUNNA, LAURA RUIZ-CANTU, ZACK STONE, JING YANG and JAMES E. DIXON, 2020. Human-scale tissues with patterned vascular networks by additive manufacturing of sacrificial sugar-protein composites Acta Biomaterialia. 113, 339-349
• SOMIRAA S. SAID, HODA M. ELTAHER and LABIBA K. EL-KHORDAGUI, 2019. Chapter 5 - Biomedical applications of composite resorbable fibers. In: VALENTINA GRUMEZESCU and ALEXANDRU MIHAI GRUMEZESCU, eds., Materials for Biomedical Engineering Elsevier. 127 - 155
• HODA M. ELTAHER, SOMIRAA S. SAID and LABIBA K. EL-KHORDAGUI, 2018. 13 - Drug delivery for cardiac regeneration. In: INAMUDDIN, ABDULLAH M. ASIRI and ALI MOHAMMAD, eds., Applications of Nanocomposite Materials in Drug Delivery Woodhead Publishing. 283 - 321
• PARMENTER, CHRISTOPHER D. J., FAY, MICHAELW., HARTFIELD, CHERYL and ELTAHER, HODA M., 2016. Making the Practically Impossible "Merely Difficult"-Cryogenic FIB Lift-Out for "Damage Free" Soft Matter Imaging MICROSCOPY RESEARCH AND TECHNIQUE. 79(4), 298-303
• ELTAHER HM, YANG J, SHAKESHEFF K and DIXON JE, 2016. Highly efficient intracellular transduction in three-dimensional gradients for programming cell fate Acta Biomaterialia. 41, 181-192