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Patients and members of the public can get involved in our research in many different ways. Involving patients and the public in our research helps us to answer many research questions. The needs of all of our volunteers are always considered throughout the research process.
We often need volunteers for a wide range of our research studies. Each study follows a carefully designed protocol that has been approved by local ethics committees. Some of the studies may also provide a small inconvenience allowance. You would have to undergo safety screening before participating in any of our research studies. Please note that you cannot start to participate in a new medical research study within 3 months of finishing a different one.
If you would like to volunteer to participate in one of our studies, please see a list of the research projects we are currently recruiting for below.
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This Sodium Study aims to measure how the concentration of sodium in the kidneys changes when a fluid is infused into the body, in order to improve our understanding of how the human body responds to this fluid. An increased understating will help doctors to improve intravenous fluid infusion techniques in patients.
The study consists of three visits. The first will be a screening visit at the David Greenfield Human Physiology Unit within the medical school at QMC (~45mins). The second and third visit will be in the morning at the Sir Peter Mansfield Imaging Centre on the University of Nottingham main campus (~4hrs). Where you will have MRI scans while receiving a standard rehydrating infusion into a vein in your arm.
You will be offered an inconvenience allowance as well as a copy of your MRI images.
To find out further information, please contact us via the link below:
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Loss of muscle mass and function is a common problem for those who suffer from Crohn’s disease in which could affect their quality of life.
Our PINC Study aims to compare how well children, aged 12 - 17, with Crohn’s Disease absorb and digest protein when compared to children without Crohn's Disease. The aim is to link the way they metabolise protein to their muscle mass by measuring this through a scan called an MRI. We will investigate protein digestion and absorption and link these findings to whole body muscle mass.
Participants will receive travel expenses to and from the QMC and an amazon voucher at study visits as a thank you.
Please complete the PINC Study form via the link below if you are interested in participating.
PINC Study Form
The TRF study examines the effect of overnight fasting on energy metabolism and muscle protein synthesis.
Recent research shows that timing of nutritional intake and daily periods of fasting may have important health effects. We have recently shown that extending habitual daily periods of fasting to 16 hours per day improves metabolism and the ability of skeletal muscle to take up amino acids, the building blocks of protein. We are interested in studying whether a single episode of prolonged overnight fast (~16 hours), when compared to a normal overnight fast of 10 hours, has a similar effect.
It is common for those who suffer from Crohn’s disease to experience loss of muscle mass, (also known as, sarcopenia) which is known to affect quality of life through decreased muscle function and changes in metabolism. It is currently unknown why Crohn’s disease patients lose muscle mass; with one explanation being a reduced ability to digest and absorb the proteins required to maintain muscle mass. To investigate this, we will use a special labelled protein (Casein) that will allow us to track the digestion and absorption of protein we eat into new muscle and tell us how this differs in healthy people (people without Crohn’s) to patients with Crohn’s disease.
David Greenfield Human Physiology Unit School of Life Sciences Medical School University of Nottingham Nottingham, NG7 2UH