Rebecca Joseph

Contact

• workRoom 1502 Tower Building
  University Park
  Nottingham
  NG7 2RD
  UK
• work0115 74 86678
• Rebecca.Joseph@nottingham.ac.uk

Biography

I am an epidemiologist in Lifespan & Population Health, School of Medicine, and conduct research into antidepressant safety using routinely-collected health data. I joined the university in 2018 after completing a PhD in epidemiology at the University of Manchester.

Expertise Summary

Keywords:

epidemiology, pharmacoepidemiology, electronic health records, routinely-collected data, mental health, antidepressants

Research Summary

My research is part of the Mental Health & Technology theme of the NIHR Nottingham Biomedical Research Centre. We perform epidemiological research into the use and safety of antidepressants.… read more

Recent Publications

• JOSEPH, R.M., JACK, R.H., MORRISS, R., KNAGGS, R.D., BUTLER, D., HOLLIS, C., HIPPISLEY-COX, J. and COUPLAND, C., 2022. The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records BMC Medicine. 20(1), 43
• JOSEPH RM, JACK RH, MORRISS R, KNAGGS RD, HOLLIS C, HIPPISLEY-COX J and COUPLAND C, 2021. PROTOCOL: A cohort study examining the association between mirtazapine and mortality risk in adults with a diagnosis of depression medRxiv. Preprint Server, 2021.02.08.21250305
• JACK RH, JOSEPH RM, COUPLAND C, BUTLER D, HOLLIS C, MORRISS RM, KNAGGS RD, CIPRIANI A, CORTESE S and HIPPISLEY-COX J, 2020. Secondary care specialist visits made by children and young people prescribed antidepressants in primary care: a descriptive study using the QResearch database. BMC Medicine. 18, 93
• PYE, S.R., SHEPPARD, T., JOSEPH, R.M., LUNT, M., GIRARD, N., HAAS, J.S., BATES, D.W., BUCKERIDGE, D. L., STAA, T.P., TAMBLYN, R. and DIXON, W.G., 2018. Assumptions made when preparing drug exposure data for analysis have an impact on results: An unreported step in pharmacoepidemiology studies Pharmacoepidemiology and Drug Safety. 27(7), 781-788

• View all publications

Current Research

My research is part of the Mental Health & Technology theme of the NIHR Nottingham Biomedical Research Centre. We perform epidemiological research into the use and safety of antidepressants. Current projects include investigating the safety of mirtazapine compared to other antidepressants and quantifying polypharmacy among users of antidepressants. These projects are set within the CPRD, a large dataset of anonymised electronic health records.

• JOSEPH, R.M., JACK, R.H., MORRISS, R., KNAGGS, R.D., BUTLER, D., HOLLIS, C., HIPPISLEY-COX, J. and COUPLAND, C., 2022. The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records BMC Medicine. 20(1), 43
• JOSEPH RM, JACK RH, MORRISS R, KNAGGS RD, HOLLIS C, HIPPISLEY-COX J and COUPLAND C, 2021. PROTOCOL: A cohort study examining the association between mirtazapine and mortality risk in adults with a diagnosis of depression medRxiv. Preprint Server, 2021.02.08.21250305
• JACK RH, JOSEPH RM, COUPLAND C, BUTLER D, HOLLIS C, MORRISS RM, KNAGGS RD, CIPRIANI A, CORTESE S and HIPPISLEY-COX J, 2020. Secondary care specialist visits made by children and young people prescribed antidepressants in primary care: a descriptive study using the QResearch database. BMC Medicine. 18, 93
• PYE, S.R., SHEPPARD, T., JOSEPH, R.M., LUNT, M., GIRARD, N., HAAS, J.S., BATES, D.W., BUCKERIDGE, D. L., STAA, T.P., TAMBLYN, R. and DIXON, W.G., 2018. Assumptions made when preparing drug exposure data for analysis have an impact on results: An unreported step in pharmacoepidemiology studies Pharmacoepidemiology and Drug Safety. 27(7), 781-788
• JOSEPH, R.M., VAN STAA, T.P., LUNT, M., ABRAHAMOWICZ, M. and DIXON, W.G., 2018. Exposure measurement error when assessing current glucocorticoid use using UK primary care electronic prescription data. Pharmacoepidemiology & Drug Safety. In Press,
• JOSEPH, R.M., SOAMES, J., WRIGHT, M., SULTANA, K., STAA, T.P. and DIXON, W.G., 2018. Supplementing electronic health records through sample collection and patient diaries: A study set within a primary care research database Pharmacoepidemiology and Drug Safety. 27(2), 239-242
• JOSEPH, R.M., RAY, DW,, KEEVIL, B., VAN STAA, T.P . and DIXON, W.G., 2018. Low salivary cortisol levels in patients with rheumatoid arthritis exposed to oral glucocorticoids: a cross-sectional study set within UK electronic health records. RMD Open. 4(2), e000700
• JOSEPH, R.M., MOVAHEDI, M., DIXON, W.G. and SYMMONS, D.P.M., 2017. Risks of smoking and benefits of smoking cessation on hospitalisations for cardiovascular events and respiratory infection in patients with rheumatoid arthritis: a retrospective cohort study using the Clinical Practice Research Datalink RMD Open. 3(2), e000506
• JOSEPH, R.M., MOVAHEDI, M., DIXON, W.G. and SYMMONS, D.P.M., 2016. Smoking-Related Mortality in Patients With Early Rheumatoid Arthritis: A Retrospective Cohort Study Using the Clinical Practice Research Datalink Arthritis Care & Research. 68(11), 1598-1606
• JOSEPH, R.M., HUNTER, A.L., RAY, D.W. and DIXON, W.G., 2016. Systemic glucocorticoid therapy and adrenal insufficiency in adults: A systematic review Seminars in Arthritis and Rheumatism. 46(1), 133-141
• BLACK, R.J., JOSEPH, R.M., BROWN, B., MOVAHEDI, M., LUNT, M. and DIXON, W.G., 2015. Half of UK patients with rheumatoid arthritis are prescribed oral glucocorticoid therapy in primary care: a retrospective drug utilisation study Arthritis Research & Therapy. 17(1), 375