Sir Peter Mansfield Imaging Centre

Microimaging

Microimaging is a type of MRI technique limited to small sample sizes but high magnetic field strengths. Microimaging enables structural and functional imaging of tissues and cells at very high resolution down to histological length scales.  

microimaging

 

Coordinator: Dr. Galina Pavlovskaya

Research

The methodology allows to enhance visualization of disease relevant histological features but enables also the development of novel MRI contrast protocols that can be translated for clinical, whole body precision imaging MRI scans.  We successfully applied this methodology to visualise cell monolayers in model lung epithelium, microbleeds and microstructure in brain specimens, highlight sodium distribution in human placenta in health and disease, characterise the diminishment of skin sodium storage in Diabetes, to monitor osteoarthritis progression in cartilage specimen during compression relaxation cycle.